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Psychiatry General

Psychological factors in personal and clinical recovery in bipolar disorder.

Nov 26, 2020

Research into bipolar disorder (BD) has primarily focused upon clinical recovery (CR), i.e. symptom reduction, and overlooked personally meaningful recovery outcomes emphasized by service users. Perso...

Metabolomic analysis to detect urinary molecular changes associated with bipolar depression.

Nov 26, 2020

Bipolar disorder (BD) is a debilitating mental disorder with complex clinical manifestations and low diagnostic accuracy. Depressive episodes are most common in the course of BD with high comorbidity ...

Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity.

Nov 26, 2020

Synaptotagmin-7 (Syt7) probably plays an important role in bipolar-like behavioral abnormalities in mice; however, the underlying mechanisms for this have remained elusive. Unlike antidepressants that...

Prevalence of early-onset GDM and associated risk factors in a university hospital in Thailand.

Nov 26, 2020

This retrospective cohort study aimed to determine prevalence of GDM diagnosed before 24 weeks of gestation (early-onset GDM) and evaluate associated risk factors and compare pregnancy outcomes betw...

Standardized exercise training is feasible, safe, and effective in pulmonary arterial and chronic thromboembolic pulmonary hypertension: results from a large European multicentre randomized controlled trial.

Nov 26, 2020

This prospective, randomized, controlled, multicentre study aimed to evaluate efficacy and safety of exercise training in patients with pulmonary arterial (PAH) and chronic thromboembolic pulmonary hy...

Associations of the gut microbiome and clinical factors with acute GVHD in allogeneic HSCT recipients.

Nov 26, 2020

Acute graft-versus-host disease (aGVHD) is a leading cause of transplantation-related mortality after allogeneic hematopoietic stem cell transplantation (aHSCT). 16S ribosomal RNA (16S rRNA) gene-base...

Maternal dietary patterns are associated with susceptibility to a depressive-like phenotype in rat offspring.

Nov 26, 2020

Environmental factors such as maternal diet, determine the pathologies that appear early in life and can persist in adulthood. Maternally modified diets provided through pregnancy and lactation increa...

"Opening the door to somebody who has a chance." - The experiences and perceptions of public safety personnel towards a public restroom overdose prevention alarm system.

Nov 26, 2020

Opioid overdose deaths have surged due to fentanyl in the illicit opioid supply, which causes overdose more rapidly than other opioids. Public restrooms are venues where fentanyl overdoses commonly oc...

Oxidative stress associated metabolic adaptations regulate radioresistance in human lung cancer cells.

Nov 26, 2020

Differential inherent and acquired radioresistance of human lung cancer cells contribute to poor therapeutic outcome and tumor recurrence after radiotherapy. Inherent radioresistance of lung cancer ce...

Breast cancer endocrine therapy adherence in health professional shortage areas: Unique effects on patients with mental illness.

Nov 26, 2020

Evaluate whether breast cancer endocrine therapy adherence is affected by access to primary and mental health care, particularly among at-risk patients with mental illness.The study included 21,892 SE...

Changing trends in the types of drug used and infectious disease prevalence among drug users in jiangsu province, china.

Nov 26, 2020

In recent years, a boom of synthetic drugs, especially methamphetamine has been documented in China, however, the situation in Jiangsu was unclear. The objective of this study was to evaluate the chan...

The cardioprotective and anxiolytic effects of Chaihujialonggumuli granule on rats with anxiety after acute myocardial infarction is partly mediated by suppression of CXCR4/NF-κB/GSDMD pathway.

Nov 26, 2020

Over-expression of CXCR4 activates nuclear translocation of NF-κB, induces high expression of NLRP3, GSDMD, IL-1β and IL-18, which promotes severe inflammatory response following myocardial infarcti...

Contingency management for tobacco smoking during opioid addiction treatment: Implementation challenges.

Nov 26, 2020

Tobacco smoking prevalence in opioid addiction patients is approximately six times that of the general population, highlighting the need for novel interventions. A pilot/feasibility study was conducte...

The pattern of FP-CIT PET in pure white matter hyperintensities-related vascular parkinsonism.

Nov 23, 2020

To determine whether vascular parkinsonism (VaP) patients with visually normal dopamine transporter (DAT) scans have presynaptic dopaminergic depletion.We enrolled 23 VaP patients who had parkinsonism...

The effect of Subthalamic nucleus deep brain stimulation on verb and noun naming in Turkish-Speaking Parkinson's disease patients.

Nov 23, 2020

Parkinson's disease (PD) is associated with an action language deficit. Subthalamic nucleus deep brain stimulation (STN DBS) deteriorates verbal fluency, but may improve verb naming more than nouns in...

Digital phenotyping: towards replicable findings with comprehensive assessments and integrative models in bipolar disorders.

Nov 23, 2020

Digital phenotyping promises to unobtrusively obtaining a continuous and objective input of symptomatology from patients' daily lives. The prime example are bipolar disorders, as smartphone parameters...

Dysfunctional frontal activation of mismatch negativity in panic disorder: A magnetoencephalographic study.

Nov 23, 2020

Mismatch negativity (MMN) or its magnetic counterpart (MMNm) is a neurophysiological signal to reflect the automatic change-detection ability. However, MMN studies in patients with panic disorder (PD)...

Impact of Childhood Trauma and Attachment on Resilience in Remitted Patients with Bipolar Disorder.

Nov 23, 2020

Childhood trauma has been reported to be associated with severe course of illness, insecure attachment, and lower resilience in bipolar disorder. We aimed to examine the impact of childhood trauma on ...

Comparison of machine learning algorithms for the prediction of five-year survival in oral squamous cell carcinoma.

Nov 23, 2020

Machine learning analyses of cancer outcomes for oral cancer remain sparse compared to other types of cancer like breast or lung. The purpose of the present study was to compare the performance of mac...

Attention-deficit/hyperactivity disorder and oral health literacy exert an influence on the occurrence of dental caries in early adolescence.

Nov 23, 2020

Little is known regarding the influence of psychosocial factors on dental caries at early adolescence. The study aimed to investigate associations between family environment, attention-deficit/hyperac...

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