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DSM-5

Low-to-Moderate Alcohol Intake Associated with Lower Risk of Incidental Depressive Symptoms: A Pooled Analysis of Three Intercontinental Cohort Studies.

Mar 08, 2021

The existing findings of the longitudinal impact of low-to-moderate drinking on symptomatic depression were controversial, as results ranged from finding no association to finding both a protective an...

[Diagnostics and Therapy 24/7? Artificial Intelligence as a Challenge and Opportunity in Psychiatry and Psychotherapy].

Mar 04, 2021

The aim of the article is to enable a fundamental understanding of the potentials and requirements of Artificial Intelligence (AI) for psychiatrists in the present and for the development of future wo...

Omega-3 fatty acid in ultra-high-risk psychosis: A systematic review based on functional outcome.

Mar 04, 2021

Among different types of poly unsaturated fatty acids, omega-3 fatty acids (FA) play a substantial role in brain development and functioning. This review was designed to evaluate and synthesize availa...

Cortical thickness and subcortical volume abnormalities in male crack-cocaine users.

Feb 25, 2021

Crack-cocaine offers a higher risk of abuse than intranasal and intravenous use of cocaine. Yet, current treatments remain disappointing and our understanding of the mechanism of crack-cocaine neuroto...

Symptom Burden and Medication Use Among Patients With Nontuberculous Mycobacterial Lung Disease.

Feb 22, 2021

Respiratory diseases caused by nontuberculous mycobacteria (NTM) have become a significant concern for patients and healthcare providers. We aimed to compare symptoms experienced during the past two w...

[Concepts of nymphomania in the German academic psychiatry: Changes over the last two centuries].

Feb 18, 2021

This chronology aims to provide an overview of the views on nymphomania in the history of German academic psychiatry over the past 200 years.The aim of this study was to answer the following questions...

Long term antidepressant use in a cohort of older people.

Feb 18, 2021

Depression is the most common mental health problem in older adults and untreated is associated with significant burden of illness for patients. This study aimed to examine longitudinal patterns of an...

Dysregulation of phospholipase and cyclooxygenase expression is involved in Schizophrenia.

Feb 15, 2021

Schizophrenia (SZ) is a severe mental disease with highly heterogeneous clinical manifestations and pathological mechanisms. Schizophrenia is linked to abnormalities in cell membrane phospholipids and...

Construct and criterion validity of patient-reported outcomes (PROs) for depression: A clinimetric comparison.

Feb 01, 2021

A number of patient-reported outcomes (PROs) have been developed but insufficient attention has been devoted to the assessment of their clinimetric properties. Clinimetrics, the science of clinical me...

The effects of KaiXinSan on depression and its association with lipid profiles: A randomized, double-blinded, placebo-controlled trial.

Feb 01, 2021

Traditional Chinese medicine (TCM) KaiXinSan (KXS) has been used to treat depressed patients for a long time, but its potential underlying mechanisms have not been fully understood.KXS could mitigate ...

The Independent Association of Prestroke Psychiatric Symptoms and Acute Phase Delirium with Poststroke Mortality at One Year in Nigeria.

Jan 28, 2021

Undetected acute phase delirium contributes to high poststroke mortality in sub-Saharan Africa (SSA). The present study adds to existing literature by examining the association of prestroke psychiatri...

Cytokines changes associated with electroconvulsive therapy in patients with treatment-resistant depression: a Meta-analysis.

Jan 28, 2021

One third of depressive patients do not achieve remission after several steps of treatment and are considered as treatment resistant. Electroconvulsive therapy (ECT) improves symptoms in 70 to 90% of ...

Safety and tolerability of lumateperone 42 mg: An open-label antipsychotic switch study in outpatients with stable schizophrenia.

Jan 18, 2021

Lumateperone is a mechanistically novel agent FDA-approved for the treatment of schizophrenia. Efficacy and favorable tolerability of lumateperone were demonstrated in 2 short-term placebo-controlled ...

Prevalence of and factors associated with nightmares in the elderly in a population based cohort study.

Dec 31, 2020

Nightmares are extremely unpleasant and vivid recurring dreams that are accompanied with awakening during sleep. However, earlier studies were mostly conducted with children and adults, with very few ...

[Communication and Mental Health: Characteristics related to empathy in primary care physicians in Chapecó, Santa Catarina, Brazil].

Dec 31, 2020

In Brazil, the provision of mental health care in primary care centers has gained strategic importance, as it ensures that users will be able to attend these services within their communities, and emp...

What works for mental health problems in youth? Survey of real-world experiences of treatments and side effects.

Dec 03, 2020

Despite youth being the most common age group for onset of mental disorders, there is less knowledge on the benefits and harms of treatments in young people. In addition, efficacy data from randomized...

Greater Socioeconomic Disadvantage is Associated with Worse Symptom Severity at Initial Presentation in Patients Seeking Care for Lumbar Disc Herniation.

Nov 16, 2020

Retrospective, observational study.To determine the association of patient socioeconomic disadvantage, insurance type, and other characteristics on presenting symptom severity in patients with isolate...

Influence of Depressive Symptoms on the Outcome of Lumbar Spine Fusion - a 5-year Follow-up Study.

Nov 16, 2020

Prospective follow-up study.The aim of this study was to assess if depressive symptoms change the outcome of lumbar spine fusion (LSF) surgery at a 5-year follow-up.Previous reports of the influence o...

Loneliness during the first half-year of COVID-19 Lockdowns.

Nov 12, 2020

During the first 6-months of the COVID-19 pandemic, the primary weapons against the spread of the virus have included local government orders for restriction of movement and broad implementation of fa...

Evaluation of long-acting injectable antipsychotics with the corresponding oral formulation in a cohort of patients with schizophrenia: a real-world study in Spain.

Oct 22, 2020

To date, only a few studies compared some long-acting injectables (LAIs) antipsychotics showing similar symptom improvement, relapse rates and adherence to treatment. We evaluated the use of LAIs anti...