Mar 19, 2020

An increasing trend in opioid consumption has been observed worldwide in last decades. However, data related to opioid utilization in hospital settings is scarce. The aim of this study was to determin...

Mar 19, 2020

This study aimed at identifying characteristics of individuals who are most likely to benefit from long-term opioid therapy in terms of reduction in pain severity and improved mental health-related qu...

Mar 19, 2020

Opioid use by pregnant women is an understudied consequence associated with the opioid epidemic, resulting in a rise in the incidence of neonatal opioid withdrawal syndrome (NOWS) and lifelong neurobe...

Mar 10, 2020

Retrospective database study.We sought to investigate trends and risk factors for new onset anxiety and/or depression within six months after elective spine surgery.Surgery represents a stressful expe...

Mar 10, 2020

To evaluate the SUMMIT-07 trial opioid withdrawal results of NKTR-181 (oxycodegol), a new molecular entity mu-opioid receptor agonist.Phase 3, enriched-enrollment, double-blind, randomized-withdrawal ...

Mar 10, 2020

Vertebroplasty is a percutaneous minimally invasive procedure indicated for vertebral collapse pain treatment. Among the known complications of the procedure is the augmented risk of new vertebral fra...

Mar 10, 2020

While primary care clinicians are being trained to use buprenorphine for the treatment of Opioid Use Disorder (OUD) in order to increase access to addiction treatment, it is not known what impact suc...

Mar 10, 2020

Understanding hepatitis C virus (HCV) transmission among people who inject drugs (PWID) is essential for HCV elimination. We aimed to differentiate reinfections from treatment failures and to identify...

Feb 28, 2020

Raddi (Anacardiaceae) is popularly known in Brazil as and has pharmacological use as an astringent, antidiarrheal, anti-inflammatory, depurative, diuretic, and antifebrile agent. Although the neurop...

Feb 28, 2020

Prescription opioid overdose has increased markedly and is of great concern among injured workers receiving workers' compensation insurance. Given the association between high daily dose of prescripti...

Feb 28, 2020

Transcutaneous electrical nerve stimulation (TENS) is primarily used for pain, but might be useful for various other physical symptoms, including nausea, fatigue, dyspnea, and constipation. However, f...

Feb 28, 2020

The purpose of this study was to investigate the presence of chronic diseases in patients with oral leukoplakia (OL) compared to controls matched for age group, gender, smoking and alcohol use.This ca...

Feb 28, 2020

A substantial share of fatal drug overdoses is missing information on specific drug involvement, leading to under-reporting of opioid-related death rates and a misrepresentation of the extent of the o...

Feb 25, 2020

Lidocaine infusion for pain control has been used for years. While some centers transition from continuous infusion lidocaine to oral mexiletine, there are no published studies to guide this conversio...

Feb 25, 2020

Studies have shown barriers to appropriate narcotic use in the Middle East have negatively impacted patient outcomes. This study aimed to explore health professionals' perspectives regarding opioid us...

Feb 25, 2020

Substance use is common in women of reproductive age, but limited data exist on the dental health of their children, including risk of caries. We conducted a longitudinal cohort study of 790,758 infan...

Feb 25, 2020

Morphine and its derivatives play inevitably important role in the μ-opioid receptor (MOR) targeted antinociception. A structure-activity relationship study is presented for novel and known orvinol a...

Feb 25, 2020

DCC netrin 1 receptor (DCC) affects the structure and function of the dopamine circuitry, which in turn affects the susceptibility to developing addiction. In a previous study, we found that single nu...

Feb 17, 2020

To evaluate the effects of an enhanced recovery after minimally invasive surgery (MIS-ERAS) protocol on opioid requirements and post-operative pain in patients undergoing minimally invasive hysterecto...

Feb 17, 2020

HCV treatment as prevention (TasP) strategies can contribute to HCV micro-elimination, yet complimentary interventions like opioid agonist therapies (OAT) and syringe services programs (SSP) may impro...