Pain General
Jun 02, 2020
Overall survival also extended with conjugate treatment In a small, phase II trial, patients with advanced gastric cancer were far more likely to respond to conjugate therapy with trastuzumab deruxte...
Jun 01, 2020
To measure differences in post-operative opioid usage and pain scores between pre- and post-Enhanced Recovery after Surgery (ERAS®) radical cystectomy (RC) patients in an effort to optimize outcomes....
Jun 01, 2020
Our aim was to investigate the relationship between coexisting cluster headache (CH) and migraine with anxiety and depression during active cluster bouts, and how symptoms change during remission.We a...
Jun 01, 2020
The purpose of this review is to summarize the role of avoidance behavior in headache-related disability and overview relevant clinical implications.Avoidance occupies a central role in contemporary p...
Jun 01, 2020
Primary headaches are less common and differ in presentation in older versus younger individuals. Secondary headaches become more common among older patients.Diagnosis and management of headaches in t...
Jun 01, 2020
There is now evidence that schizophrenia and especially deficit schizophrenia (DefSCZ) (a phenotype characterized by negative symptoms) is accompanied by activated immune-inflammatory pathways. A subs...
Jun 01, 2020
Opioids are a mainstay for pain management after total joint arthroplasty (TJA). The prevalence and risk factors for prolonged opioid use after TJA are important to understand to help slow the opioid ...
Jun 01, 2020
It is widely accepted that the pathophysiology and treatment of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) could be considerably improved. The heterogeneity of ME/CFS and the confusio...
Jun 01, 2020
Although studies report a high prevalence rate of restless legs syndrome (RLS) among patients with multiple sclerosis (PwMS) ranging from 13.3 to 65.1%, little is known about the causes of this relati...
Jun 01, 2020
Major depressive disorder is associated with lowered mood, anxiety, anhedonia, sleep problems, and cognitive impairments. Many of these functions are regulated by μ-opioid receptor (MOR) system. Prec...
Jun 01, 2020
To calculate in- and out-of-field neutron spectra and dose equivalent, using Monte Carlo (MC) simulation, for a Mevion gantry-mounted passively scattered proton system in craniospinal irradiation. An ...
Jun 01, 2020
The regulation of the phosphorylation of mitogen activated protein kinases (MAPKs) is essential for cellular processes such as proliferation, differentiation, survival and death. Mutations within the ...
Jun 01, 2020
Constipation occurs in up to 71.7% (33/46) of hospital inpatients taking opioid analgesics. Co-prescribing laxatives with opioid analgesics is recommended to prevent opioid-induced constipation.This s...
Jun 01, 2020
A systematic review and analysis of data from several rheumatoid arthritis metabolomics studies attempts to determine which metabolites can be used as potential biomarkers for the diagnosis of rheumat...
Jun 01, 2020
Baricitinib, is an oral Janus kinase (JAK)1/JAK2 inhibitor approved for the treatment of rheumatoid arthritis (RA) that was independently predicted, using artificial intelligence (AI)-algorithms, to b...
May 28, 2020
Dexmedetomidine is widely used as an adjunct to general anesthesia. In this study, we evaluated the effects of perioperative dexmedetomidine infusion on postoperative analgesia in patients undergoing ...
May 28, 2020
Pain is the most important clinical feature of acute pancreatitis (AP); however, its specific mechanism is currently unclear. In this study, we showed that AP caused an increase in nitric oxide (NO) s...
May 28, 2020
Introduction Multiple barriers have been described for reducing opioid prescribing by primary care providers. We describe a quality improvement report on the effects of a series of focused interventio...
May 28, 2020
The aim of this study was to determine if headache profile can predict future disability in patients with TTH.Eighty-three patients with TTH were recruited. To be included in the study participants ne...
May 28, 2020
Migraine surgery is an increasingly popular treatment option for migraine patients. The lesser occipital nerve (LON) is a common trigger point for headache pathologies, but there is a paucity of resea...