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Pain General

Opioid antagonists are associated with a reduction in the symptoms of schizophrenia: a meta-analysis of controlled trials.

Jun 11, 2020

Current treatments for the symptoms of schizophrenia are only effective for positive symptoms in some individuals, and have considerable side effects that impact compliance. Thus, there is a need to i...

Assessing the burden and spatial distribution of Taenia solium human neurocysticercosis in Ecuador (2013-2017).

Jun 11, 2020

Estimating the burden of neglected tropical diseases is a valuable tool to support policymakers in the resource allocation for control and elimination of these diseases. Spatial analysis allows to ide...

Impact of migraine on workplace productivity and monetary loss: a study of employees in banking sector in Malaysia.

Jun 11, 2020

Productivity and monetary loss due to migraine in the workplace may be substantial. This study aimed to determine the impact of migraine on productivity and monetary lost among employees in the bankin...

Shift work and migraine: A systematic review.

Jun 11, 2020

Migraine is a chronic neurological disorder characterized by recurrent attacks of headache, mainly affecting the working age population with a great socioeconomic impact. The etiology of migraine is s...

Lactate Production Precedes Inflammatory Cell Recruitment in Arthritic Ankles: an Imaging Study.

Jun 11, 2020

Inflammation is involved in many disease processes. However, accurate imaging tools permitting diagnosis and characterization of inflammation are still missing. As inflamed tissues exhibit a high rate...

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2.

Jun 11, 2020

In communities with high rates of coronavirus disease 2019, reports have emerged of children with an unusual syndrome of fever and inflammation.To describe the clinical and laboratory characteristics ...

Circulating tumor necrosis factor-α DNA are elevated in psoriasis.

Jun 11, 2020

In psoriasis, tumor necrosis factor (TNF)-α is a key pro-inflammatory cytokine that activates keratinocytes to produce other inflammatory mediators. In addition, increased serum or plasma TNF-α leve...

Evaluating upadacitinib for the treatment of rheumatoid arthritis.

Jun 11, 2020

The introduction of JAKs inhibitors for the treatment of rheumatoid arthritis represents a promising new era in the management of the disease. New compounds under investigation, like upadacitinib, wit...

Behavioral Therapy Preferences in People With Migraine

Jun 09, 2020

Published studies have shown that biofeedback, cognitive behavioral therapy, and relaxation are safe and well-tolerated nonpharmacologic strategies for migraine prevention and may provide long-term be...

Migraine and Diet.

Jun 08, 2020

Migraine is characterized by recurrent attacks of disabling headaches, often accompanied by sensory and motor disturbances. Clinical manifestations of migraine are influenced by dietary behaviors and ...

Galcanezumab: A Review in the Prevention of Migraine and Treatment of Episodic Cluster Headache.

Jun 08, 2020

Galcanezumab (Emgality) is a humanized monoclonal antibody targeting the calcitonin gene-related peptide (CGRP), thereby inhibiting its physiological activity, with CGRP playing a key role in the path...

Metabolic syndrome, depression, and fibromyalgia syndrome prevalence in patients with irritable bowel syndrome: A case-control study.

Jun 08, 2020

Although both metabolic syndrome (MetS) and irritable bowel syndrome (IBS) have been linked with altered gut microbiota, only a few studies investigated the association between them. Hence, we aimed t...

Sharing the pain: an observational analysis of Twitter and pain in Ireland.

Jun 08, 2020

Studies involving Twitter and chronic pain can provide highly valuable patient-generated information. The aim of this paper was to examine pain-related tweets in Ireland over a 2-week period from 22 J...

Indentation marks, skin temperature and comfort of two cervical collars: A single-blinded randomized controlled trial in healthy volunteers.

Jun 08, 2020

Collar-related pressure ulcers (CRPU) are a problem in trauma patients with a suspicion of cervical cord injury patients. Indentation marks (IM), skin temperature (T) and comfort could play a role in ...

Exploring the effect of Colorado's recreational marijuana policy on opioid overdose rates.

Jun 08, 2020

Opioid overdose death rates have continued to spike exponentially from the start of the 21st century, creating what is known to be one of the worst public health crises in the United States. Simultane...

Buprenorphine prescription dispensing rates and characteristics following federal changes in prescribing policy, 2017-2018: A cross-sectional study.

Jun 08, 2020

Expansion of buprenorphine for opioid use disorder treatment is a core component of the opioid overdose epidemic response. The Comprehensive Addiction and Recovery Act (CARA) of 2016 authorized nurse ...

Prevalence of musculoskeletal disorders and rheumatic diseases in an Argentinean indigenous Wichi community.

Jun 08, 2020

To estimate the prevalence of musculoskeletal disorders (MSK) and rheumatic diseases in an indigenous Wichi population in Argentina.This is a cross-sectional, community-based study using the Community...

Race, Social Status, and Depressive Symptoms: A Moderated Mediation Analysis of Chronic Low Back Pain Interference and Severity.

Jun 08, 2020

Chronic low back pain (cLBP) is the leading cause of disability, with a significant societal cost. It disproportionately affects Non-Hispanic Blacks and individuals of lower socioeconomic status (SES)...

Impaired School Functioning in Children with Chronic Pain: A National Perspective.

Jun 08, 2020

The purpose of this study is to determine the association between presence of chronic pain and school functioning among school aged children (6-17▒y) using the most recent United States national dat...

Association between opioid analgesic plus benzodiazepine use and death: A case-crossover study.

Jun 08, 2020

We aimed to investigate whether concomitant use of benzodiazepines and opioids is associated with an increased risk of death in a population-based case-crossover setting.We conducted a case-crossover ...

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