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Pain General

Individualized augmented reality training reduces phantom pain and cortical reorganization in amputees: A proof of concept study.

Jun 25, 2020

Phantom limb pain (PLP) may be relieved using a visual representation of an intact limb. However, patients with distorted (telescoped) phantoms seem unable to associate with visualizations of intact l...

Systematic Review of Research Methods and Reporting Quality of Randomized Clinical Trials of Spinal Cord Stimulation for Pain.

Jun 25, 2020

This systematic review assessed design characteristics and reporting quality of published randomized clinical trials of spinal cord stimulation (SCS) for treatment of pain in adults and adolescents. T...

Comparing central pain processing in individuals with non-traumatic neck pain and healthy individuals: a systematic review and meta-analysis.

Jun 25, 2020

This systematic review and meta-analysis examined the evidence for altered central pain processing in people with non-traumatic neck pain and the relationship between central pain processing, demograp...

Activated antimicrobial peptides due to periodontal bacteria in synovial fluid - The link between psoriatic arthritis and periodontitis?

Jun 25, 2020

The impact of periodontal disease on systemic conditions has not been fully identified yet. Literature shows that the incidence of psoriatic arthritis in psoriasis-patients is higher in presence of pe...

Role of different Th17 and Treg downstream signalling pathways in the pathogenesis of Staphylococcus aureus infection induced septic arthritis in mice.

Jun 25, 2020

Septic arthritis is a condition of bone disorder caused predominantly by Staphylococcus aureus. Following the bacterial entry activated immune cells specially macrophages and dendritic cells release p...

Lower Socioeconomic Status and Co-morbid Conditions are Associated with Reduced CPAP Adherence use Among Older Adult Medicare Beneficiaries with Obstructive Sleep Apnea.

Jun 25, 2020

To examine rates of adherence to continuous positive airway pressure (CPAP) therapy among a representative sample of older adult Medicare beneficiaries with obstructive sleep apnea (OSA), and to ident...

Tolerogenic vaccines for the treatment of cardiovascular diseases.

Jun 25, 2020

Atherosclerosis is the main pathology behind most cardiovascular diseases. It is a chronic inflammatory disease characterized by the formation of lipid-rich plaques in arteries. Atherosclerotic plaque...

A Novel Vestibular Migraine Assessment Tool

Jun 23, 2020

Increasing evidence suggests that vestibular migraine (VM) is a common cause of episodic vertigo, with an estimated 2.7% of US adults having been diagnosed with the condition. “Despite being common,...

Headache in children with Sturge-Weber syndrome - Prevalence, associations and impact.

Jun 22, 2020

Sturge-Weber syndrome (SWS) is a congenital neurovascular disorder characterised by capillary-venous malformations involving the skin, brain and eye. Patients experience headache, however little is kn...

The Use of Botulinum Toxin in the Management of Headache Disorders.

Jun 22, 2020

Tremendous progress has been made in the past decades for the treatment of headache disorders. Chronic migraine is the most disabling type of headache and requires the use of acute and preventive medi...

Altered resting-state functional connectivity between subregions in the thalamus and cortex in migraine without aura.

Jun 22, 2020

Migraine is a complex and disabling neurological disorder, and the exact neurological mechanisms remain unclear. Thalamus is considered the hub of the central processing and integration of nociceptive...

Extended overview of the longitudinal pain-depression association: A comparison of six cohorts treated for specific chronic pain conditions.

Jun 22, 2020

The aim was to quantify and to compare the associations between longitudinal changes in pain and depression in different chronic pain conditions.Data were retrieved from 6 observational cohort studies...

DNA methylation and BDNF expression account for symptoms and widespread hyperalgesia in patients with Chronic Fatigue Syndrome and Fibromyalgia.

Jun 22, 2020

Epigenetics of neurotrophic factors holds the potential to unravel the mechanisms underlying the pathophysiology of complex conditions such as chronic fatigue syndrome (CFS). This study explored the ...

Alleviation of TGF-β1 induced tubular epithelial-mesenchymal transition via the δ-opioid receptor.

Jun 22, 2020

Renal fibrosis is a common pathological feature of progressive chronic kidney disease (CKD). It is indicated that transforming growth factor-β1 (TGF-β1) plays as a central mediator in renal fibrosis...

Acute pain after breast surgery and reconstruction: A two-institution study of surgical factors influencing short-term pain outcomes.

Jun 22, 2020

Acute postoperative pain following surgery is known to be associated with chronic pain development and lower quality of life. We sought to analyze the relationship between differing breast cancer exci...

Reconnecting the Brain with the Rest of the Body in Musculoskeletal Pain Research.

Jun 22, 2020

A challenge in understanding chronic musculoskeletal pain is that research is often siloed between neuroscience, physical therapy/rehabilitation, orthopedics and rheumatology which focus respectively ...

Psychosocial predictors of acute and chronic pain in adolescents undergoing major musculoskeletal surgery.

Jun 22, 2020

Acute and chronic pain delay recovery and impair outcomes after major pediatric surgery. Understanding unique risk factors for acute and chronic pain is critical to developing effective treatments for...

Once an avoider always an avoider? Return of pain-related avoidance after extinction with response prevention.

Jun 22, 2020

In exposure for chronic pain, avoidance is often forbidden (extinction with response prevention; RPE) to prevent misattributions of safety. Although exposure is an effective treatment, relapse is comm...

Chronic facial pain: different comorbidities and characteristics between neuropathic and nonneuropathic conditions.

Jun 22, 2020

The aim of this study was to investigate the association between comorbidities and chronic diseases and neuropathic and nonneuropathic orofacial pain diagnoses to suggest subclassifications of disease...

Disorders of the Aorta and Aortic Valve in Connective Tissue Diseases.

Jun 22, 2020

The incidence of aortic valve disease in inherited connective tissue disorders is well documented; however, recent studies have only begun to unravel the pathology behind this association. In this rev...

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