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Pain General

A Closer Look at Patterns in Prescription Opioid Use & Misuse Among Cancer Survivors

Aug 28, 2020

Recent reports have shown that about one-third of cancer survivors experience cancer-related pain, and prescription rates for opioids are higher for these patients than the general population. The Ame...

A Population Study of Prescribed Opioid-based Pain Reliever Use among Individuals with Mood and Anxiety Disorders in Canada.

Aug 27, 2020

In the context of the ongoing North American overdose crisis, a clear understanding of opioid prescription and usage trends is important. Although individuals with mood and/or anxiety disorders are a ...

Efficacy of an Enhanced Recovery After Surgery (ERAS) Pathway in Elderly Patients Undergoing Spine and Peripheral Nerve Surgery.

Aug 27, 2020

Elderly patients are a vulnerable patient population in elective spinal surgery. Older patients have more medical comorbidities and are also more sensitive to opiate medications. Despite this, spine a...

Treatment-Refractory Headache in the Setting of COVID-19 Pneumonia: Migraine or Meningoencephalitis? Case Report.

Aug 27, 2020

The coronavirus responsible for the COVID-19 pandemic, SARS-2-CoV, most commonly involves the respiratory tract; however, more severe cases have been found to have multi-organ involvement, including t...

A Review on the Potential Receptors of Migraine with a Special Emphasis on Cgrp to Develop an Ideal Antimigraine Drug.

Aug 27, 2020

Background and Objective: Migraine is a neurovascular syndrome associated with unilateral, throbbing headache accompanied with nausea, vomiting and photo/phonophobia. Several proteins are involved in ...

Relative Cost Differences of Initial Treatment Strategies for Newly Diagnosed Opioid Use Disorder: A Cohort Study.

Aug 27, 2020

Relative costs of care among treatment options for opioid use disorder (OUD) are unknown.We identified a cohort of 40,885 individuals with a new diagnosis of OUD in a large national de-identified clai...

Low bone mass and hypovitaminosis D in haemophilia: A single-centre study in patients with severe and moderate haemophilia A and B.

Aug 27, 2020

Haemophilia (H) is frequently associated with a multifactorial reduction in bone mineral density (BDM), but little is known about possible differences between HA and HB according to their severity.To ...

Bleeding complications during pregnancy and delivery in haemophilia carriers and their neonates in Western France: An observational study.

Aug 27, 2020

Pregnancy, delivery and the postpartum period expose haemophilia carriers, as well as their potentially affected neonates to a high risk of haemorrhagic complications.To describe bleeding complication...

Flourensia fiebrigii S.F. Blake: A medicinal plant from the Argentinean highlands with potential use as anti-rheumatic and anti-inflammatory.

Aug 27, 2020

Flourensia fiebrigii is a plant used in traditional medicine in the Argentine Calchaquí Valley as purgative, expectorant, anti-rheumatic and anti-inflammatory.The aim of this study was to analyze the...

Criteria Used for the Diagnosis of Myofascial Trigger Points in Clinical Trials on Physical Therapy: Updated Systematic Review.

Aug 27, 2020

To conduct an updated systematic review of diagnostic criteria for myofascial trigger points (MTrPs) used in clinical trials of physical therapy interventions from 2007 to 2019.MEDLINE and Physiothera...

Longitudinal Patterns of Pain Reporting among Community-dwelling Older Adults.

Aug 27, 2020

To identify and describe long-term trajectories of bothersome pain and activity-limiting pain in a population-based sample of older adults.We conducted a retrospective cohort study of 6783 community-d...

Placebo Response Reduction and Accurate Pain Reporting Training Reduces Placebo Responses in a Clinical Trial on Chronic Low Back Pain: Results from a Comparison to the Literature.

Aug 27, 2020

A literature review was conducted to compare placebo responses in a recent trial-which implemented an Accurate Pain Reporting (APR) and Placebo Response Reduction (PRR) training program-to placebo res...

Attentional bias to somatosensory stimuli in chronic pain patients: a systematic review and meta-analysis.

Aug 27, 2020

This systematic review and meta-analysis aimed to evaluate the evidence pertaining to attentional bias for painful and non-painful somatosensory stimuli in individuals with chronic pain. Eligible stud...

[Analysis of clinical features of vestibular migraine].

Aug 27, 2020

To analyze the clinical features of Vestibular migraine(VM) and provide evidence for its accurate diagnosis and medical identification of flight personnel. A total of 490 samples of VM patients we...

Alternative therapy of rheumatoid arthritis with a novel transdermal patch containing Siegesbeckiae Herba extract.

Aug 27, 2020

Siegesbeckiae Herba (SiH) is a traditional anti-rheumatic herbal medicine in China. A SiH derived product, Phynova Joint and Muscle Relief Tablets™, has been granted the UK license in 2015. Alt...

Ethanol extract of Liriodendron chinense (Hemsl.) Sarg barks attenuates hyperuricemic nephropathy by inhibiting renal fibrosis and inflammation in mice.

Aug 27, 2020

Liriodendron chinense (Hemsl.) Sarg, known as the Chinese tulip tree, has a long history of cultivation and utilization in many Asia countries, especially in China to use in traditional Chinese medici...

Treating Fibromyalgia Pain With Lidocaine

Aug 26, 2020

Previous studies indicate that chronic pain, including fibromyalgia (FM), negatively impacts quality of life (QoL) for the reportedly affected 3%-6% of the world population. “There is supportive evi...

Emerging regulatory roles of opioid peptides, endogenous morphine, and opioid receptor subtypes in immunomodulatory processes: Metabolic, behavioral, and evolutionary perspectives.

Aug 24, 2020

Integrated behavioral paradigms such as nociceptive processing coupled to anti-nociceptive responsiveness include systemically-mediated states of alertness, vigilance, motivation, and avoidance. Withi...

Psychological factors associated with substance use initiation during the COVID-19 pandemic.

Aug 24, 2020

The 2019 outbreak of the novel coronavirus (COVID-19) has had a devastating impact. Given the on-going nature of the outbreak, the deleterious toll on mental health, including substance use, is unknow...

Detecting peripheral motor nervous system involvement in chronic spinal cord injury using two novel methods: MScanFit MUNE and muscle velocity recovery cycles.

Aug 24, 2020

To examine the peripheral nervous system (PNS) in spinal cord injured (SCI) patients using two novel methods: (1) MScanFit MUNE; a motor unit number estimation method detecting motor unit loss and (2)...

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