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Pain General

High Volume Injections for Chronic Achilles Tendinopathy

Sep 10, 2020

Achilles tendinopathy (AT), or Achilles tendinitis, is an injury of the Achilles tendon, which connects the calf muscle to the heel bone. The usual care given to patients with AT does not result in po...

Manganese-enhanced MRI Reveals Changes Within Brain Anxiety and Aversion Circuitry in Rats with Chronic Neuropathic Pain- and Anxiety-like Behaviors.

Sep 10, 2020

Chronic pain often predicts the onset of psychological distress. Symptoms including anxiety and depression after pain chronification reportedly are caused by brain remodeling/recruitment of the limbic...

[Novel migraine treatment with CGRP-related monoclonal antibodies].

Sep 10, 2020

Migraine is a common and debilitating neurological disorder characterized by recurrent attacks of moderate to severe throbbing headache accompanied by nausea, vomiting and photophobia/phonophobia. Bec...

Hemorrhagic reversible cerebral vasoconstriction syndrome: A retrospective observational study.

Sep 10, 2020

Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by recurrent thunderclap headaches associated with segmental vasoconstriction of cerebral arteries, which may result in intracrani...

Characteristics of Post-Ictal Headaches in Patients with Epilepsy: a Longitudinal Study.

Sep 10, 2020

This study aimed to investigate the clinical predictors of post-ictal headache (PIH) in patients with epilepsy in a tertiary center in Brazil.302 individuals with adult-onset epilepsy were followed fo...

Ion-rich potash mining effluents affect sperm motility parameters of European perch, Perca fluviatilis, and impair early development of the common roach, Rutilus rutilus.

Sep 10, 2020

Secondary salinization of freshwater ecosystems is of increasing global concern. One of the main causes are the effluents of the potash mining industry containing high concentrations of major ions (Cl...

Prevalence of Sarcopenia and Whole-Body Composition in Rheumatoid Arthritis.

Sep 10, 2020

Rheumatoid arthritis (RA) is a chronic autoimmune disease that leads to joint deformity and disability, as well as muscle involvement. Sarcopenia is characterized by a progressive age-related loss of ...

Assessment of Interleukin 6 Gene Polymorphisms with Rheumatoid Arthritis.

Sep 10, 2020

Rheumatoid arthritis (RA) is complex autoimmune system disease and significant impact on the health of population in our world. Numerous studies confirmed that genetic factors play a crucial role in t...

Altered brainstem pain modulating circuitry functional connectivity in chronic painful Temporomandibular Disorder.

Sep 10, 2020

Evidence in preclinical models of chronic pain and human psychophysical investigations has suggested that alterations in endogenous brainstem pain-modulation circuit functioning are critical for the i...

Small-fibre pathology has no impact on somatosensory system function in patients with fibromyalgia.

Sep 10, 2020

We aimed to investigate whether small-fibre pathology, a common skin biopsy finding in patients with fibromyalgia, implies clinically important abnormalities of somatosensory system function and verif...

Psychometric Properties of the Fibromyalgia Survey Questionnaire in Chilean Women With Fibromyalgia.

Sep 10, 2020

The aim of this study was to evaluate the psychometric properties of the Chilean version of the Fibromyalgia Survey Questionnaire (FSQ).Women with fibromyalgia (FM; n = 214), women with rheumatoid art...

Intensive Multicomponent Fibromyalgia Treatment: A Translational Study to Evaluate Effectiveness in Routine Care Delivery.

Sep 10, 2020

The current study was designed to evaluate the translation of clinical trial outcomes and clinical guidelines for the treatment of fibromyalgia (FM) into an intensive multicomponent clinical program e...

Impact of Preoperative Opioid Use on 2-Year Patient-Reported Outcomes in Knee Surgery Patients.

Sep 10, 2020

The objectives of this study are to assess perioperative opioid use in patients undergoing knee surgery and to examine the relationship between preoperative opioid use and 2-year postoperative patient...

Predictors of PROMIS Physical Function at 2 Years following Knee Surgery.

Sep 10, 2020

The purpose of this study was to evaluate Patient-Reported Outcomes Measurement Information System physical function (PROMIS PF) 2 years following knee surgery, and identify preoperative factors assoc...

Differentiating Between β-Lactam Induced Serum Sickness-Like Reactions and Viral Exanthem in Children Using a Graded Oral Challenge.

Sep 10, 2020

Serum sickness-like reactions (SSLR) are defined by the presence of rash (primarily urticaria), and joint complaints (arthralgia/arthritis) that are believed to occur due to a non-IgE mediated respons...

The impact of substance use and abuse on opioid demand in lower extremity fracture surgery.

Sep 07, 2020

To describe the perioperative opioid demand in a large population of patients undergoing lower extremity fracture fixation and to evaluate mental disorders such as substance abuse as risk factors for ...

Successful engagement in buprenorphine treatment among hospitalized patients with opioid use disorder and trauma.

Sep 07, 2020

The opioid epidemic continues to cause significant morbidity and mortality. Although there are effective medications for opioid use disorder (OUD), a minority of patients receive these treatments. OUD...

Maternal oxycodone treatment causes pathophysiological changes in the mouse placenta.

Sep 07, 2020

Pregnant women are increasingly being prescribed and abusing opioid drugs. As the primary communication organ between mother and conceptus, the placenta may be vulnerable to opioid effects but also ho...

Study on the pharmacodynamics and metabolomics of five medicinal species in Atractylodes DC. on rats with rheumatoid arthritis.

Sep 07, 2020

Atractylodes DC. mainly includes Atractylodis Rhizoma and Atractylodis macrocephalae Rhizoma. According to Chinese Pharmacopoeia, Atractylodis Rhizoma is the rhizome of Atractylodes lancea (Thunb.) DC...

Risk Factors for Increased Postoperative Pain and Recommended Order Set for Postoperative Analgesic Usage.

Sep 07, 2020

An interdisciplinary pain team (IPT) was established at our institution to explore options for improving pain control in patients undergoing orthopaedic surgery by identifying traits that put a patien...

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