Pain General
Sep 14, 2020
Previous studies suggest that increased cerebrovascular reactivity might be a feature of patients who have migraine with aura (MwA). The correlation between the clinical presentation of migraine with ...
Sep 14, 2020
To describe patterns of perceived stress across stages of the migraine cycle, within and between individuals and migraine episodes as defined for this study.Individuals with migraine aged ≥18 years...
Sep 14, 2020
In spite of the prevalence of occupational neck disorders as a result of work force fluctuating from industry to sedentary office work, most cervical spine computational models are not capable of simu...
Sep 14, 2020
Veterans experience chronic pain at greater rates than the rest of society and are more likely to receive long-term opioid therapy (LTOT), which, at high doses, is theorized to induce maladaptive neur...
Sep 14, 2020
Targeted anti-IL-1β therapy may be a valuable option for the management of gouty arthritis. The present meta-analysis has evaluated the effect of canakinumab, an anti-IL-1β monoclonal antibody in go...
Sep 14, 2020
Heterozygous missense mutations in COPA, encoding coatomer protein subunit alpha (COPA), cause an interferonopathy mainly associating lung, joint and kidney involvement. This rare autoinflammatory dis...
Sep 14, 2020
The social determinants of health (SDH) are known to differentially impact outcomes from many noncommunicable diseases; however, their potential role in low back pain (LBP) is poorly defined. This rev...
Sep 14, 2020
Nocebo hyperalgesia refers to increases in perceived pain that putatively result from negative expectations regarding a nocebo stimulus (eg, an inert treatment, compared with no treatment). The precis...
Sep 14, 2020
Low back pain (LBP) is a high-burden condition that lacks routine surveillance data. Health administrative data may be used for surveillance, but their validity for measuring LBP in the general popula...
Sep 14, 2020
Active Straight Leg Raise (ASLR) is a clinical test that challenges lumbopelvic stability and have been used in low back pain patients. There are reports of positive tests in asymptomatic individuals,...
Sep 14, 2020
Fibromyalgia is commonly considered a stress-related chronic pain disorder, and daily stressors are known triggers. However, the relation between stress and pain development remains poorly defined by ...
Sep 14, 2020
In contrast to other chronic rheumatic musculoskeletal diseases such as rheumatoid arthritis, comorbidities in axial spondyloarthritis (axSpA) and their impact on disease outcomes are less well studie...
Sep 14, 2020
Fibromyalgia syndrome (FMS) is characterized by widespread musculoskeletal pain. It is more common in women than in men, and sex hormones may play a role in this predominance. Therefore, this research...
Sep 14, 2020
Interleukin-15 (IL-15) is a member of the IL-2 family of cytokines, which use receptor complexes containing the common gamma (γ) chain for signaling. IL-15 plays important roles in innate and adaptat...
Sep 14, 2020
The use of controlled substances like cocaine increases the risk of cardiovascular disease (CVD) and myocardial infarction (MI). However, outside of alcohol and tobacco, substance use is not included ...
Sep 11, 2020
Ankle sprains are one of the most common types of musculoskeletal injuries. Physiotherapy is routinely given to patients with ankle sprains. This study aims to evaluate the efficacy of supervised phys...
Sep 10, 2020
Achilles tendinopathy (AT), or Achilles tendinitis, is an injury of the Achilles tendon, which connects the calf muscle to the heel bone. The usual care given to patients with AT does not result in po...
Sep 10, 2020
Chronic pain often predicts the onset of psychological distress. Symptoms including anxiety and depression after pain chronification reportedly are caused by brain remodeling/recruitment of the limbic...
Sep 10, 2020
Migraine is a common and debilitating neurological disorder characterized by recurrent attacks of moderate to severe throbbing headache accompanied by nausea, vomiting and photophobia/phonophobia. Bec...
Sep 10, 2020
Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by recurrent thunderclap headaches associated with segmental vasoconstriction of cerebral arteries, which may result in intracrani...