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Pain General

Prior pain exposure and mere possession of a placebo analgesic predict placebo analgesia: Findings from a randomised, double-blinded, controlled trial.

Nov 02, 2020

A recent study found that merely possessing a placebo analgesic reduces pain. The current study tested for a possible moderator of this effect. Specifically, does the mere possession of a placebo anal...

Brief Acceptance and Commitment Therapy for Fibromyalgia: Feasibility and Effectiveness of a Replicated Single-Case Design.

Nov 02, 2020

Overall, the literature on the effectiveness of psychological treatments in general and those for fibromyalgia in particular has been dominated by research designs that focus on large groups and explo...

Associations between objective afternoon and evening physical activity and objective sleep in patients with fibromyalgia and insomnia.

Nov 02, 2020

Patients with fibromyalgia (FM) suffer from chronic pain, which limits physical activity and is associated with disturbed sleep. However, the relationship between physical activity, pain and sleep is ...

Adult attention deficit hyperactivity disorder in patients with fibromyalgia syndrome: Assessment and disabilities.

Nov 02, 2020

In the broader list of cognitive concerns, neuropsychological testing has shown that attentional impairment may have a specific burden in Fibromyalgia Syndrome (FMS). Preliminary observations have rep...

A systematic review of qualitative evidence on barriers to and facilitators of the implementation of opioid agonist treatment (OAT) programmes in PRISONS.

Nov 02, 2020

Opioid Agonist Treatment (OAT) programmes are regarded as a gold standard treatment for people living with Opioid Use Disorders (OUDs). However, OAT programmes are often unavailable or poorly implemen...

Overview of the molecular determinants contributing to the expression of Psoriasis and Psoriatic Arthritis phenotypes.

Nov 02, 2020

Psoriasis and psoriatic arthritis are multifactorial chronic disorders whose etiopathogenesis essentially derives from the alteration of several signalling pathways and the co-occurrence of genetic, e...

Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease.

Nov 02, 2020

Interleukin (IL)-38 belongs to the IL-1 family and is part of the IL-36 subfamily due to its binding to the IL-36 Receptor (IL-1R6). In the current study, we assessed the anti-inflammatory properties ...

MRI of superior capsular reconstruction graft and associated short-term clinical outcomes in patients with massive irreparable rotator cuff tears.

Nov 02, 2020

To assess MRI appearance of the dermal allograft and its correlation with clinical outcome following superior capsular reconstruction (SCR).This is a retrospective study of patients who underwent SCR ...

Comparison of the effects of real-time propulsive force versus limb angle gait biofeedback on gait biomechanics.

Nov 02, 2020

Reduced forward propulsion during gait, measured as the anterior component of the ground reaction force (AGRF), may contribute to slower walking speeds in older adults and gait dysfunction in individu...

Disparities in Prescription Opioid Misuse Affecting Sexual Minority Adults Are Attenuated by Depression and Suicidal Ideation.

Oct 29, 2020

Heightened rates of prescription opioid misuse have been observed among sexual minority (SM) compared with heterosexual populations. In addition, depression and suicidal ideation are risk factors for...

Use of tramadol and other analgesics following media attention and risk minimization actions from regulators: a Danish nationwide drug utilization study.

Oct 29, 2020

To describe the use of tramadol and other analgesics in Denmark focusing on the impact of media attention (June and December 2017) and regulatory actions (September 2017 and January 2018) on the use o...

Migraine and sleep disorders: a systematic review.

Oct 29, 2020

Migraine and sleep disorders are common and often burdensome chronic conditions with a high prevalence in the general population, and with considerable socio-economic impact and costs.The existence of...

Statin for Migraine Headache: Is It Worthwhile?

Oct 29, 2020

Migraine is a severe primary headache disorder that affects about 12% of the population, and it often occurs along with nausea, vomiting, and extreme sensitivity to light and sound. For patients with ...

in migraine: A case-control study on the causes and consequences of the non-use of triptans in chronic migraine patients.

Oct 29, 2020

is the excessive and inadequately justified concern about potential risks of triptans. We evaluated causes and consequences of non-use of triptans in chronic migraine.Observational study with case-co...

Association of Therapies With Reduced Pain and Improved Quality of Life in Patients With Fibromyalgia: A Systematic Review and Meta-analysis.

Oct 29, 2020

Fibromyalgia is a chronic condition that results in a significant burden to individuals and society.To investigate the effectiveness of therapies for reducing pain and improving quality of life (QOL) ...

Small Fiber Polyneuropathy Is Associated With Non-Bladder-Centric Interstitial Cystitis/Bladder Pain Syndrome Patients.

Oct 29, 2020

Interstitial cystitis/bladder pain syndrome (IC/BPS) comprises at least 2 phenotypes. Bladder centric patients typically demonstrate low bladder capacity (BC), often with Hunner lesion (HL), whereas n...

A training program for fibromyalgia management: A 5-year pilot study.

Oct 29, 2020

We studied the effects of a specific cardio training program lasting 5 years on pain and quality of life in fibromyalgia patients.An observational longitudinal pilot study was conducted in 138 fibro...

Countermeasures for preventing and treating opioid overdose.

Oct 29, 2020

The only medication available currently to prevent and treat opioid overdose (naloxone) was approved by the Food and Drug Administration (FDA) nearly 50 years ago. Because of its pharmacokinetic and p...

Comparison between Arch Zones in Modified Frozen Elephant Trunk Procedure for Complex Thoracic Aortic Diseases.

Oct 29, 2020

The aim of this study is to compare postoperative outcomes and follow-up of two different modifications facilitating surgical technique of frozen elephant trunk (FET) procedure for complex thoracic ao...

Sox2 and Canonical Wnt Signaling Interact to Activate a Developmental Checkpoint Coordinating Morphogenesis with Mesoderm Fate Acquisition.

Oct 29, 2020

Animal embryogenesis requires a precise coordination between morphogenesis and cell fate specification. During mesoderm induction, mesodermal fate acquisition is tightly coordinated with the morphogen...

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