Nov 02, 2020

Opioid Agonist Treatment (OAT) programmes are regarded as a gold standard treatment for people living with Opioid Use Disorders (OUDs). However, OAT programmes are often unavailable or poorly implemen...

Nov 02, 2020

Psoriasis and psoriatic arthritis are multifactorial chronic disorders whose etiopathogenesis essentially derives from the alteration of several signalling pathways and the co-occurrence of genetic, e...

Nov 02, 2020

Interleukin (IL)-38 belongs to the IL-1 family and is part of the IL-36 subfamily due to its binding to the IL-36 Receptor (IL-1R6). In the current study, we assessed the anti-inflammatory properties ...

Nov 02, 2020

To assess MRI appearance of the dermal allograft and its correlation with clinical outcome following superior capsular reconstruction (SCR).This is a retrospective study of patients who underwent SCR ...

Nov 02, 2020

Reduced forward propulsion during gait, measured as the anterior component of the ground reaction force (AGRF), may contribute to slower walking speeds in older adults and gait dysfunction in individu...

Oct 29, 2020

Heightened rates of prescription opioid misuse have been observed among sexual minority (SM) compared with heterosexual populations. In addition, depression and suicidal ideation are risk factors for...

Oct 29, 2020

To describe the use of tramadol and other analgesics in Denmark focusing on the impact of media attention (June and December 2017) and regulatory actions (September 2017 and January 2018) on the use o...

Oct 29, 2020

Migraine and sleep disorders are common and often burdensome chronic conditions with a high prevalence in the general population, and with considerable socio-economic impact and costs.The existence of...

Oct 29, 2020

Migraine is a severe primary headache disorder that affects about 12% of the population, and it often occurs along with nausea, vomiting, and extreme sensitivity to light and sound. For patients with ...

Oct 29, 2020

is the excessive and inadequately justified concern about potential risks of triptans. We evaluated causes and consequences of non-use of triptans in chronic migraine.Observational study with case-co...

Oct 29, 2020

Fibromyalgia is a chronic condition that results in a significant burden to individuals and society.To investigate the effectiveness of therapies for reducing pain and improving quality of life (QOL) ...

Oct 29, 2020

Interstitial cystitis/bladder pain syndrome (IC/BPS) comprises at least 2 phenotypes. Bladder centric patients typically demonstrate low bladder capacity (BC), often with Hunner lesion (HL), whereas n...

Oct 29, 2020

We studied the effects of a specific cardio training program lasting 5 years on pain and quality of life in fibromyalgia patients.An observational longitudinal pilot study was conducted in 138 fibro...

Oct 29, 2020

The only medication available currently to prevent and treat opioid overdose (naloxone) was approved by the Food and Drug Administration (FDA) nearly 50 years ago. Because of its pharmacokinetic and p...

Oct 29, 2020

The aim of this study is to compare postoperative outcomes and follow-up of two different modifications facilitating surgical technique of frozen elephant trunk (FET) procedure for complex thoracic ao...

Oct 29, 2020

Animal embryogenesis requires a precise coordination between morphogenesis and cell fate specification. During mesoderm induction, mesodermal fate acquisition is tightly coordinated with the morphogen...

Oct 29, 2020

Fibroblast-like synoviocytes (FLSs) are important non-immune cells located mostly in the inner layer of the synovium. Indeed, these cells are specialized mesenchymal cells, implicated in collagen home...

Oct 29, 2020

The objective was to evaluate the relationships between multimorbidity and overall fatigue as well as fatigue subdomains in patients with rheumatoid arthritis (RA).A cross-sectional study of a populat...

Oct 29, 2020

Studies in axial spondyloarthritis (AxSp) have shown that intensity of pain, anxiety, depression, and inflammatory activity are associated with poor sleep quality.To describe mood and sleep disorders ...

Oct 29, 2020

Preterm infants show a higher incidence of cognitive, social and behavioral problems, even in the absence of major medical complications during their stay in the neonatal intensive care unit (NICU). S...