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Pain General

Induction of remission in female rheumatoid arthritis patients is associated with stabilization of myocardial abnormalities: a prospective cardiac magnetic resonance follow-up study.

Nov 30, 2020

: To study whether female patients with active rheumatoid arthritis (RA) have myocardial abnormalities and whether progression of myocardial involvement can be attenuated by disease-modifying anti-rhe...

Nocardiosis in A Patient With Pemphigus Foliaceus Treated With Rituximab.

Nov 30, 2020

Rituximab is a chimeric human/murine monoclonal anti-CD20 antibody. This agent is an effective therapeutic option in severe types of pemphigus. However, rituximab may cause opportunistic infections if...

Structure based peptide design, molecular dynamics and MM-PBSA studies for targeting C terminal dimerization of NFAT5 DNA binding domain.

Nov 30, 2020

NFAT5 as a transcription factor with an established role in osmotic stress response, has also been revealed to be active under numerous settings, including pathological conditions such as diabetic mic...

Position Paper on Post-Traumatic Headache: The Relationship Between Head Trauma, Stress Disorder, and Migraine.

Nov 30, 2020

Traumatic brain injury (mTBI) is a major public health concern, with mild TBI (mTBI) constituting the vast majority of the injuries. Post-traumatic headache (PTH) is one of the most frequent symptoms ...

Vets With Pain-PTSD Comorbidity Showed Worse Outcomes Than Those With Pain Alone

Nov 27, 2020

“There are important reasons to study chronic pain and PTSD together,” says Matthew J. Bair, MD, MS. Chronic pain and PTSD co-occur frequently. This comorbidity leads to significant adverse effec...

A Review on the Triggers of Pediatric Migraine with the Aim of Improving Headache Education.

Nov 26, 2020

Although migraines are common in children and adolescents, they have a robustly negative impact on the quality of life of individuals and their families. The current treatment guidelines outline the b...

Nystagmus and Vertigo in Acute Vestibular Migraine Attacks: Response to Non-Invasive Vagus Nerve Stimulation.

Nov 26, 2020

Vestibular migraine (VM) is the most common neurologic cause of vertigo in adults, but there are no currently-approved rescue therapies. This study describes the benefits of non-invasive vagus nerve s...

Cross-sectional study of psychosocial and pain-related variables among chronic pain patients during a time of social distancing imposed by the coronavirus disease 2019 (COVID-19) pandemic.

Nov 26, 2020

The COVID-19 pandemic has had a tremendous impact, including on individuals with chronic pain. The social distancing policies necessary to slow the spread of SARS-CoV-2 have involved increased levels ...

A picture is worth a thousand words: linking fibromyalgia pain widespreadness from digital pain drawings with pain catastrophizing and brain cross-network connectivity.

Nov 26, 2020

Pain catastrophizing is prominent in chronic pain conditions such as fibromyalgia, and has been proposed to contribute to the development of pain widespreadness. However, the brain mechanisms responsi...

"Opening the door to somebody who has a chance." - The experiences and perceptions of public safety personnel towards a public restroom overdose prevention alarm system.

Nov 26, 2020

Opioid overdose deaths have surged due to fentanyl in the illicit opioid supply, which causes overdose more rapidly than other opioids. Public restrooms are venues where fentanyl overdoses commonly oc...

Metabolic syndrome in rheumatoid arthritis patients: Relationship among its clinical components.

Nov 26, 2020

Metabolic syndrome (MetS) prevalence in rheumatoid arthritis (RA) patients is known to vary considerably across the world. This study aimed to determine the prevalence of MetS in RA patients from west...

Secukinumab and ustekinumab treatment in psoriatic arthritis: results of a direct comparison.

Nov 26, 2020

To evaluate the characteristics of patients (pts) with PsA treated by ustekinumab (UST) or secukinumab (SEK) and to compare real-world persistence of UST and SEK in PsA.In this retrospective, national...

Assessing reasons for decreased primary care access for individuals on prescribed opioids: an audit study.

Nov 26, 2020

Many primary care clinics are resistant to accept new patients taking prescription opioids for chronic pain. It is unclear how much of this practice is specific to individuals who may be perceived to ...

Reduction in movement-evoked pain and fatigue during initial 30-minute TENS treatment predicts TENS responders in women with fibromyalgia.

Nov 26, 2020

We previously showed 1-month of Transcutaneous Electrical Nerve Stimulation (TENS) reduces movement-evoked pain and fatigue in women with fibromyalgia (FM). Using data from this study (Fibromyalgia Ac...

Involvement of TACAN, a mechanotransducing ion channel, in inflammatory but not neuropathic hyperalgesia in the rat.

Nov 26, 2020

TACAN (Tmem120A), a mechanotransducing ion channel highly expressed in a subset of nociceptors, has recently been shown to contribute to detection of noxious mechanical stimulation. In the present stu...

Changing trends in the types of drug used and infectious disease prevalence among drug users in jiangsu province, china.

Nov 26, 2020

In recent years, a boom of synthetic drugs, especially methamphetamine has been documented in China, however, the situation in Jiangsu was unclear. The objective of this study was to evaluate the chan...

Calcitonin Gene-Related Peptide Monoclonal Antibody Use for the Preventive Treatment of Refractory Headache Disorders in Adolescents.

Nov 26, 2020

Monoclonal antibodies to calcitonin gene-related peptide or its receptor have clinical trial evidence in adults with headache, but data are lacking in adolescents. The objective of this study was to d...

Visceral adiposity in patients with psoriatic arthritis and psoriasis alone and its relationship with metabolic and cardiovascular risk.

Nov 26, 2020

Fat mass distribution, especially in the abdominal visceral region, has been rarely evaluated in patients with PsA or psoriasis (PsO).Patients with PsA and patients with PsO alone were evaluated and c...

Contingency management for tobacco smoking during opioid addiction treatment: Implementation challenges.

Nov 26, 2020

Tobacco smoking prevalence in opioid addiction patients is approximately six times that of the general population, highlighting the need for novel interventions. A pilot/feasibility study was conducte...

Neuraxial Anesthesia is Associated with Decreased Pain Scores and PACU Opioid Requirements Compared with General Anesthesia in Hip Arthroscopy.

Nov 23, 2020

We sought to identify the immediate post-operative differences in opioid use, pain scores, and post-anesthesia care unit (PACU) length of stay (LOS) after hip arthroscopy related to the type of anesth...

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