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Pain General

Effects on Mood and Health-Related Quality of Life in Women with Fibromyalgia.

Dec 07, 2020

Fibromyalgia syndrome is a chronic rheumatic disorder characterized by generalized and widespread musculoskeletal pain. It is associated with several secondary symptoms such as psychological and pain-...

Effectiveness of Active Therapy-Based Training to Improve the Balance in Patients with Fibromyalgia: A Systematic Review with Meta-Analysis.

Dec 07, 2020

Balance impairment is a frequent disorder in patients with fibromyalgia (FMS), increasing the risk of falls and decreasing physical function and quality of life. In recent years, the use of active the...

Fentanyl and fentanyl analogs in the illicit stimulant supply: Results from U.S. drug seizure data, 2011-2016.

Dec 07, 2020

U.S. research examining the illicit drug supply remains rare even though the information could help reduce overdoses. Relatively little is known regarding how often opioids are found in stimulants and...

Prevalence and socio-demographic correlates of law enforcement involvement among treatment-seeking adult males with opioid use disorder.

Dec 07, 2020

Use of various substances, including opioid use is often associated with coming in contact with the law- enforcement agencies. Data are scarce on the unique socio-demographic and clinical correlates f...

What Mediates Treatment Effects in a Pre-surgery Physiotherapy Treatment in Surgical Candidates with Degenerative Lumbar Spine Disorders? A Mediation and Conditional Process Analysis of the PREPARE Randomized Controlled Trial.

Dec 07, 2020

Treatment guidelines recommend targeting both physical and psychological factors in interventions for degenerative lumbar spine disorders. Studying treatment mechanisms gives information on key factor...

Deep Cervical Plexus Block for Neck and Shoulder Pain Due to Myofascial Pain: A Randomized Clinical Trial.

Dec 07, 2020

Myofascial pain is one of the most common causes of regional pain yet with no definitive treatment modality. This randomized clinical trial was conducted to assess the efficacy of deep cervical plexus...

Sphingomyelin is involved in multisite musculoskeletal pain: evidence from metabolomic analysis in two independent cohorts.

Dec 07, 2020

Metabolic dysfunction has been suggested to be involved in musculoskeletal pain; however, few studies have identified metabolic markers associated with multisite musculoskeletal pain (MSMP). This stud...

Facet Joint Replacement: Intermediate- and Long-Term Outcome in a Large Case Series.

Dec 07, 2020

 The long-term outcome of facet joint replacement (FJR) still is to be proven. We present a prospective case series of 26 (male-to-female ratio of 1:1; mean age: 61 years) patients undergoing FJR ...

Acetazolamide ameliorates the severity of collagen-induced arthritis in rats: Involvement of inducing synovial apoptosis and inhibiting Wnt/β-catenin pathway.

Dec 07, 2020

We previously revealed that the overexpression of synovial aquaporin 1 (AQP1) aggravated collagen-induced arthritis (CIA) in rats via regulating β-catenin signaling. This study was to demonstrate the...

Differences in 30-day complications associated with total ankle arthroplasty and ankle arthrodesis: A matched cohort study.

Dec 07, 2020

The objective of this study was to identify whether total ankle arthroplasty (TAA) was associated with greater risk for 30-day complications and/or greater financial burden in comparison to ankle arth...

Synovial fluid presepsin as a novel biomarker for the rapid differential diagnosis of native joint septic arthritis from crystal arthritis.

Dec 07, 2020

To investigate whether presepsin can be used as a novel biomarker to differentiate between native joint septic arthritis (NJSA) and crystal arthritis (CA).This study included 75 patients diagnosed wit...

Possible mechanism and potential application of anti-opioid effect of diazepam-binding inhibitor.

Dec 03, 2020

Our previous study has demonstrated that porcine diazepam-binding inhibitor (pDBI) and its active fragments, pDBI-16 and pDBI-19, have inhibition effect on morphine analgesia in mice. The present stud...

The Effectiveness of Dorsal Root Ganglion Neurostimulation for the Treatment of Chronic Pelvic Pain and Chronic Neuropathic Pain of the Lower Extremity: A Comprehensive Review of the Published Data.

Dec 03, 2020

To evaluate the effectiveness of dorsal root ganglion neurostimulation for the treatment of refractory, focal pain in the pelvis and lower extremities.Systematic review.The primary outcome was ≥50% ...

Cerebral fractional amplitude of low-frequency fluctuations may predict headache intensity improvement following acupuncture treatment in migraine patients.

Dec 03, 2020

To explore how baseline resting-state cerebral function predicts clinical outcomes of acupuncture treatment for migraine.One hundred migraine patients and 46 healthy subjects were recruited. Patients ...

Sex differences in reporting of concussion symptoms in adults.

Dec 03, 2020

To examine differences in concussion symptom reporting between female and male adults considering current psychological symptoms such as anxiety and depression and pre-injury factors in order to ident...

Migraine and cardiovascular risk factors: A clinic-based study.

Dec 03, 2020

The relation between migraine and vascular risk factors is an unclear issue. Furthermore, the reasons for chronification are still unknown. Probably, the age-related risk and other factors leading to ...

Altered regulation of negative affect in patients with fibromyalgia: A diary study.

Dec 03, 2020

Fibromyalgia is characterized by widespread musculoskeletal pain and often accompanied by cognitive and emotional problems. Adaptation to fibromyalgia may therefore also rely on one's ability to regul...

Pathogenic mechanisms of lipid mediator lysophosphatidic acid in chronic pain.

Dec 03, 2020

A number of membrane lipid-derived mediators play pivotal roles in the initiation, maintenance, and regulation of various types of acute and chronic pain. Acute pain, comprising nociceptive and inflam...

Dorsal Atlantoaxial Ligament Hypertrophy as a Cause for Clinical Signs in Dogs with Dens Abnormalities.

Dec 03, 2020

The objective of this study is to suggest clinical and subclinical atlantoaxial (AA) instability as a cause for dorsal AA ligament hypertrophy responsible for clinical signs in dogs with dens abnormal...

Treatment of Neck Pain with Opioids in the Primary Care Setting: Trends and Geographic Variation.

Dec 03, 2020

Neck pain is a leading cause of years lived with disability and is often managed with opioid medications in primary care settings, though this is contraindicated by national guidelines. The aim of thi...

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