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Pain General

Barriers and facilitators to PDMP IS Success in the US: A systematic review.

Jan 04, 2021

Prescription Drug Monitoring Programs (PDMP) help prevent prescription drug misuse and promote appropriate pain management. Despite these benefits and PDMP mandates in most states, PDMPs face challeng...

Type 1 helper T cells generate CXCL9/10-producing T-bet effector B cells potentially involved in the pathogenesis of rheumatoid arthritis.

Jan 04, 2021

Efficacy of B-cell depletion therapy highlights the antibody-independent effector functions of B cells in rheumatoid arthritis (RA). Given type 1 helper T (Th1) cells abundant in synovial fluid (SF) o...

How can neighborhood environments facilitate management of osteoarthritis: A scoping review.

Jan 04, 2021

The association between neighborhood environments and health outcomes has long been recognized, but the importance of environmental factors is less well examined in osteoarthritis (OA). We aimed to gi...

Association of interleukin-17 gene polymorphisms with the onset of Rheumatoid Arthritis.

Jan 04, 2021

Rheumatoid Arthritis (RA) is an autoimmune disorder where multiple cytokines including IL-17A and IL-17F produced by T helper cell 17 (Th17), contribute to its pathogenesis. By initiating inflammatory...

Application of the OMERACT synovitis ultrasound scoring system in juvenile idiopathic arthritis: a multicenter reliability exercise.

Dec 31, 2020

To evaluate the reliability of the OMERACT paediatric ultrasound (US) synovitis definitions and scoring system in JIA.Thirteen sonographers analysed 75 images for the presence/absence of elementary le...

Measuring complications of serious pediatric emergencies using ICD-10.

Dec 31, 2020

To create definitions for complications for 16 serious pediatric conditions using the International Classification of Diseases, 10th Revision, Clinical Modification or Procedure Coding System (ICD-10-...

Stepped Exercise Program for Patients With Knee Osteoarthritis : A Randomized Controlled Trial.

Dec 31, 2020

Evidence-based models are needed to deliver exercise-related services for knee osteoarthritis efficiently and according to patient needsTo examine a stepped exercise program for patients with knee ost...

Yishen-tongbi decoction inhibits excessive activation of B cells by activating the FcγRIIb/Lyn/SHP-1 pathway and attenuates the inflammatory response in CIA rats.

Dec 31, 2020

Rheumatoid arthritis (RA) is a chronic autoimmune disease. Strong evidence supports that excessive activation of B cells plays a critical role in the pathogenesis of RA. Fc gamma receptor b (FcγRIIb)...

Opioid-Induced Respiratory Depression in Pediatric Palliative Care Patients with Severe Neurological Impairment-A Scoping Literature Review and Case Reports.

Dec 31, 2020

Pediatric Palliative Care (PPC) addresses children, adolescents, and young adults with a broad spectrum of underlying diseases. A substantial proportion of these patients have irreversible conditions ...

Novel synthetic treatment options for migraine.

Dec 31, 2020

: Migraine is one of the most common neurological disorders. Nowadays, the 5-HT receptor agonists, namely triptans, are considered as the standard of care for migraine acute treatment. However, tripta...

Muscle Fascia Changes in Patients with Occipital Neuralgia, Headache, or Migraine.

Dec 31, 2020

In an ongoing effort to understand the pathogenesis of occipital neuralgia/headache/migraine, it is critical to describe the anatomical/tissue changes encountered during surgery. Greater occipital ner...

Orthostatic Headache in Children Including Postural Tachycardia Syndrome and Orthostatic Hypotension: A Near-Infrared Spectroscopy Study.

Dec 31, 2020

Although head and/or neck pain attributed to orthostatic hypotension is included in international guidelines, its mechanisms and relevance remain unknown. This study examined the term's relevance and ...

Clustering fibromyalgia patients: A combination of psychosocial and somatic factors leads to resilient coping in a subgroup of fibromyalgia patients.

Dec 31, 2020

Coping strategies and their efficacy vary greatly in patients suffering from fibromyalgia syndrome (FMS).We aimed to identify somatic and psychosocial factors that might contribute to different coping...

Effects of neuro-adaptive electrostimulation therapy on pain and disability in fibromyalgia: A prospective, randomized, double-blind study.

Dec 31, 2020

To evaluate the effectiveness of non-invasive neuro-adaptive electrostimulation (NAE) therapy for treating chronic pain and disability in patients with fibromyalgia.A prospective, randomized, sham-con...

Effects of clinical Pilates exercises in individuals with fibromyalgia: A randomized controlled trial.

Dec 31, 2020

This study aimed to investigate the effects of clinical Pilates exercises in patients with fibromyalgia (FM) and to compare the effects of one-to-one and group-based exercise methods.A total of 42 wom...

Analyzing the Effects of Stimulant Abuse in Patients With Burns

Dec 25, 2020

Illicit drug use—including use of stimulants like methamphetamine, amphetamines, and cocaine—continues to be a growing problem throughout the United States. Research has shown that the misuse of i...

An alternative analysis of illicit opioid use during treatment in a randomized trial of extended-release naltrexone versus buprenorphine-naloxone: A per-protocol and completers analysis.

Dec 24, 2020

The distinct pharmacological properties and clinical uses of extended-release naltrexone (XR-NTX) and sublingual buprenorphine-naloxone (BUP-NX) present challenges in analyzing patient outcomes.We con...

Short communication: Systematic review on effectiveness of micro-induction approaches to buprenorphine initiation.

Dec 24, 2020

Micro-induction is a novel buprenorphine induction approach that seeks to avoid withdrawal and minimize precipitated withdrawal, both barriers to standard inductions. We aimed to synthesize evidence o...

[Network Meta-analysis of oral Chinese patent medicine in treatment of migraine].

Dec 24, 2020

To systemically assess the clinical efficacy of oral Chinese patent medicine for migraine by using network Meta-analysis. Four Chinese databases(CNKI, VIP, WanFang, CBM), three English databases(Medli...

[Systematic review and Meta-analysis on randomized controlled trial of efficacy and safety for acupuncture versus Flunarizine in treatment of migraine].

Dec 24, 2020

To systematically evaluate the efficacy and safety of acupuncture versus Flunarizine hydrochloride in the treatment of migraine. Four Chinese databases(CNKI, VIP, WanFang, CBM), three English database...

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