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Pain General

Input-output slope curve estimation in neural stimulation based on optimal sampling principles.

May 13, 2021

This paper discusses some of the practical limitations and issues, which exist for the input--output (IO) slope curve estimation (SCE) in neural, brain and spinal, stimulation techniques. The drawback...

Imbalance in Axial-plane Rotator Cuff Fatty Infiltration in Posteriorly Worn Glenoids in Primary Glenohumeral Osteoarthritis: An MRI-based Study.

May 13, 2021

Fatty infiltration of the rotator cuff evaluated with CT has been associated with asymmetric glenoid wear and humeral head subluxation in patients with glenohumeral arthritis. The relationship between...

Achieving reliable pain change scores for individuals in postoperative phase: carefully choose sampling density, test length, and administration mode.

May 13, 2021

Despite tremendous efforts to increase the reliability of pain measures and other self-report instruments, improving or even evaluating the reliability of change scores has been largely neglected. In ...

Evaluation of four field portable devices for the rapid detection of mitragynine in suspected kratom products.

May 10, 2021

The development of a method for the rapid screening of food and drug products for constituents such as mitragynine, the most abundant alkaloid found in Mitragyna speciosa (kratom) plant leaves, has be...

Genome-wide association study identifies the virulence-associated marker in Streptococcus suis serotype 2.

May 10, 2021

Streptococcus suis (S. suis) has been reported to be a highly invasive pathogen in swine, which causes severe infections like meningitis, arthritis and septicemia, and also a zoonotic agent for humans...

What do patients value learning about pain? A mixed-methods survey on the relevance of target concepts after pain science education.

May 10, 2021

Pain education is a popular treatment approach for persistent pain that involves learning a variety of concepts about pain (ie, target concepts), which is thought to be an important part of recovery. ...

Evaluation of analgesic interaction between morphine, maropitant and dexmedetomidine in dogs undergoing ovariohysterectomy.

May 06, 2021

To compare the analgesic effect of morphine combined with maropitant and/or dexmedetomidine to morphine alone given at a higher dose, and to evaluate the pharmacokinetics of the drug combinations, in ...

Predictive Performance of Oximetry to Detect Sleep Apnea in Patients Taking Opioids.

May 06, 2021

Long-term use of opioids for treatment of chronic pain is associated with significant risks including worsening unrecognized or untreated sleep apnea that may increase morbidity and mortality. Overnig...

Fentanyl-related substance scheduling as an effective drug control strategy.

May 06, 2021

Fentanyl is now the primary driver of the current opioid crisis. Fentanyl and its analogues are subject to the Controlled Substances Act of 1970, the Controlled Substances Analogue Enforcement Act of ...

Own experience in the diagnosis and treatment of elongated styloid process syndrome.

May 06, 2021

<b>Introduction:</b> The aim of the study was to present selected cases with Eagle's syndrome diagnosed and treated at the Department of Otolaryngology, Laryngological Oncology, Audiology ...

The impact of Coronavirus disease 2019 (COVID-19) pandemic on migraine disorder.

May 06, 2021

To evaluate the impact of the Coronavirus disease of 2019 (COVID-19) pandemic on patients with migraine.Self-reported data from a migraine tracking smartphone application, Migraine Buddy, were used. D...

Galcanezumab Provides Consistent Efficacy Throughout the Dosing Interval Among Patients with Episodic and Chronic Migraine: A Post Hoc Analysis.

May 06, 2021

The consistency of the treatment effect of galcanezumab throughout the dosing interval is examined in patients with episodic and chronic migraine.This study was a post hoc analysis of clinical trial d...

Osteopathic medicine for fibromyalgia: a sham-controlled randomized clinical trial.

May 06, 2021

Patients with fibromyalgia (FM) frequently resort to osteopathic or chiropractic treatment, despite very weak supporting evidence. We aimed to assess the efficacy of osteopathic manipulation in FM in ...

Interoceptive Sensibility, Alexithymia, and Emotion Regulation in Individuals Suffering from Fibromyalgia.

May 06, 2021

People suffering from fibromyalgia syndrome report various difficulties in emotional processing, possibly resulting from changes in bodily perception (interoception). In our study, we investigated the...

Bioactive lipid mediators in the initiation and resolution of inflammation after spinal cord injury.

May 06, 2021

Neuroinflammation is a prominent feature of the response to CNS trauma. It is also an important hallmark of various neurodegenerative diseases in which inflammation contributes to the progression of p...

Sagittal reduction of spinal deformity: superior versus lateral screw-rod connection.

May 06, 2021

Introduction Spinal malalignment can greatly impact a patient's quality of life. Various sagittal parameters are used as realignment goals; however, about 50% of patients end up being under-corrected ...

Association between interleukin-1 alpha rs1800587 polymorphism and rheumatoid arthritis: A meta-analysis.

May 06, 2021

No consistent results have been reached on the relationship of interleukin-1 (IL-1) rs1800587 polymorphism with the susceptibility to rheumatoid arthritis (RA) so far. Therefore, the current meta-anal...

The efficacy and safety of silver needle in the treatment of rheumatoid arthritis: A protocol of randomized controlled trial.

May 06, 2021

Rheumatoid arthritis is a kind of chronic crippling disease, the condition is complex, the course of the disease is repeated, seriously affecting the quality of life of patients. Adverse reactions and...

Rheumatoid Arthritis and Associated-Interstitial Lung Disease: Mortality Rates and Trends.

May 06, 2021

The burden of rheumatoid arthritis (RA) and RA-associated interstitial lung disease (RA-ILD) in recent years has not been well characterized.In this study, we sought to describe RA and RA-ILD-related ...

β2 adrenergic receptor mediates noradrenergic action to induce CREB phosphorylation in satellite glial cells of dorsal root ganglia to regulate visceral hypersensitivity.

May 06, 2021

Sympathoneuronal outflow into dorsal root ganglia (DRG) is suggested to be involved in sympathetically maintained chronic pain, which is mediated by norepinephrine (NE) action on DRG cells. The presen...

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