Pain General
May 20, 2021
Musculoskeletal disorders are a leading cause of disability adjusted life years (DALY) in the world. We aim to describe the prevalence and to compare the DALYs and loss of health state utilities (LHSU...
May 20, 2021
The Symptom Impact Questionnaire (SIQR), now used for over a decade, has strong psychometric properties based on patients' subjective questionnaire data and correlations with other general measures of...
May 20, 2021
Fibromyalgia (FM) is a chronic syndrome characterized by heterogeneous clinical manifestations, and knowing this variability can help to develop tailored treatments. To understand better the heterogen...
May 20, 2021
Across a wide range of Froude speeds, non-human primates such as macaques prefer to use grounded and aerial running when locomoting bipedally. Both gaits are characterized by bouncing kinetics of the ...
May 20, 2021
Chemoreceptors that detect O2 and CO2/pH regulate ventilation. However, recent work shows that lactate ions activate arterial chemoreceptors independent of pH to stimulate breathing. Although lactate ...
May 20, 2021
This study aimed to compare posterolateral fusion with transforaminal lumbar interbody fusion (PLF + TLIF) and PLF only in terms of revision surgery rates and complications, as well as functional and ...
May 20, 2021
Much is said about precision medicine, but its real significance and the possibility of making it a real possibility is far from certain. Several studies in each of the autoimmune diseases have provid...
May 20, 2021
To evaluate the safety of treatment strategies in patients with early rheumatoid arthritis (RA).Systematic searches of MEDLINE, EMBASE and PubMed were conducted up to September 2020. Double-blind rand...
May 20, 2021
Tocilizumab is a humanised monoclonal antibody to the interleukin-6 (IL-6) receptor which was first approved for use in refractory rheumatoid arthritis almost a decade ago. Since then, its use has exp...
May 20, 2021
Previous studies have established a bidirectional relationship between sleep and pain, and mood has been proposed as a mediator of this relationship. There are only a limited number of longitudinal st...
May 20, 2021
Persistent postsurgical pain (PPSP) is common after breast and thoracic surgeries. Understanding which risk factors consistently contribute to PPSP will allow clinicians to apply preventive strategies...
May 20, 2021
Clinical models of chronic low back pain (cLBP) highlight the role of excessive attention to pain and kinesiophobia on the origin of disability. At the motor control level, various mechanisms are invo...
May 19, 2021
“With an absence of effective, licensed disease-modifying treatments for OA, attention has turned to identifying clinically important targets for clinical trials,” explains Thomas Perry, PhD. “S...
May 17, 2021
“To address the growing focus on using patient-reported outcomes (PRO) and individual-specific outcomes when assessing osteoarthritis (OA), a strategy that defines clinically meaningful improvement ...
May 17, 2021
To assess the efficacy and safety of jakinibs for the treatment of active rheumatoid arthritis (RA) in patients with an inadequate response or intolerance to conventional synthetic or biologic disease...
May 17, 2021
Dorsal root ganglion field stimulation (GFS) relieves evoked and spontaneous neuropathic pain by use-dependent blockade of impulse trains through the sensory neuron T-junction, which becomes complete ...
May 17, 2021
Chronic pain is associated with reduced quality of life, increased medical expenditures, and significant economic costs. Chronic pain is among the most common chronic conditions in the United States, ...
May 17, 2021
Pain is a complex experience that involves sensation, emotion, and cognition. The subjectivity of the traditional pain measurement tools has expedited the interest in developing neuroimaging technique...
May 13, 2021
Shared decision making (SDM) in knee osteoarthritis (OA) is essential to optimizing patient-centered care and involves clinicians and patients collaborating to make decisions using the best available ...
May 13, 2021
This paper discusses some of the practical limitations and issues, which exist for the input--output (IO) slope curve estimation (SCE) in neural, brain and spinal, stimulation techniques. The drawback...