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Pain General

The mapping of cortical activation by near-infrared spectroscopy might be a biomarker related to the severity of fibromyalgia symptoms.

Aug 05, 2021

The delta value of oxyhemoglobin (Δ-HbO) determined by functional near-infrared spectroscopy at prefrontal cortex (PFC) and motor cortex (MC) based on primary (25 °C) and secondary (5 °C) thermal...

The association between body mass index and fibromyalgia severity: data from a cross-sectional survey of 2339 patients.

Aug 05, 2021

Various studies have shown that overweight and obesity are central features of FM, but the real impact of a high BMI on clinical severity in patients with FM is still controversial. The aim of this st...

Hierarchical clustering by patient-reported pain distribution alone identifies distinct chronic pain subgroups differing by pain intensity, quality, and clinical outcomes.

Aug 05, 2021

In clinical practice, the bodily distribution of chronic pain is often used in conjunction with other signs and symptoms to support a diagnosis or treatment plan. For example, the diagnosis of fibromy...

The Significance of Depression for Short-term Readmission and Mortality After a Pneumonia Admission.

Aug 05, 2021

Depression is highly prevalent among hospitalized patients with pneumonia. At discharge, these patients transfer to a less care-intensive home-based setting. Nevertheless, little is known on the progn...

Structured Reporting of Whole-Body Trauma CT Scans Using Checklists: Diagnostic Accuracy of Reporting Radiologists Depending on Their Level of Experience.

Aug 05, 2021

 Evaluation of the diagnostic accuracy of a checklist-style structured reporting template in the setting of whole-body multislice computed tomography in major trauma patients depending on the level ...

Activated peripheral blood B cells in rheumatoid arthritis and relationship to anti-TNF treatment and response: randomized clinical trial for anti-TNF effects on B cells.

Aug 05, 2021

B cells can become activated in germinal center (GC) reactions in secondary lymphoid tissue and ectopic GCs in synovium in RA that may be TNF and lymphotoxin (LT) dependent. Here we characterized the ...

Research agenda setting with children with juvenile idiopathic arthritis: lessons learned.

Aug 05, 2021

Several health research agendas have successfully been developed with adults but rarely with children. Children are still seldom recognized as possessing credible knowledge about their own body and li...

Effectiveness of App-Delivered, Tailored Self-management Support for Adults With Lower Back Pain-Related Disability: A selfBACK Randomized Clinical Trial.

Aug 05, 2021

Lower back pain (LBP) is a prevalent and challenging condition in primary care. The effectiveness of an individually tailored self-management support tool delivered via a smartphone app has not been r...

Association of Dose Tapering With Overdose or Mental Health Crisis Among Patients Prescribed Long-term Opioids.

Aug 05, 2021

Opioid-related mortality and national prescribing guidelines have led to tapering of doses among patients prescribed long-term opioid therapy for chronic pain. There is limited information about risks...

Pharmacologic therapies for neuropathic pain: an assessment of reporting biases in randomized controlled trials.

Aug 05, 2021

Several different reporting biases cited in scientific literature have raised concerns about the overestimation of effects and the subsequent potential impact on the practice of evidence-based medicin...

Yoga for treating low back pain: a systematic review and meta-analysis.

Aug 02, 2021

Yoga is frequently used for back pain relief. However, evidence was judged to be of only low- or moderate. To assess the efficacy and safety of yoga in patients with low back pain a meta-analysis was ...

PRMT7 modulates neuronal excitability by interacting with NaV1.9.

Aug 02, 2021

Human NaV1.9 (hNaV1.9), encoded by SCN11A, is preferentially expressed in nociceptors, and its mutations have been linked to pain disorders. NaV1.9 could be a promising drug target for pain relief. Ho...

Diversity of inhibitory and excitatory parvalbumin interneuron circuits in the dorsal horn.

Aug 02, 2021

Parvalbumin-expressing interneurons (PVINs) in the spinal dorsal horn are found primarily in laminae II inner and III. Inhibitory PVINs (iPVINs) play an important role in segregating innocuous tactile...

Recommendations for Dosing & Administering Medical Cannabis for Chronic Pain

Jul 31, 2021

Despite a need for more robust evidence, many patients with chronic pain are being treated with medical cannabis and cannabinoids. In the Journal of Cannabis Research, the Global Task Force on Dosing ...

Substance use and suicide outcomes among self-injured trauma patients.

Jul 29, 2021

Research indicates alcohol (AUD) or substance (SUD) use disorders and acute alcohol or drug use serve as risk factors for suicidal behaviors and death both distally and proximally to a suicidal event....

Ultra-Low Energy Cycled Burst Spinal Cord Stimulation Yields Robust Outcomes in Pain, Function, and Affective Domains: A Subanalysis From Two Prospective, Multicenter, International Clinical Trials.

Jul 29, 2021

DeRidder's burst stimulation design has become a key spinal cord stimulation (SCS) waveform because it reduces the intensity of pain as well as its associated emotional distress. The brain pathways un...

Adolescent pain, anxiety, and depressive problems: a twin study of their co-occurrence and the relationship to substance use.

Jul 29, 2021

Data on the etiological factors underlying the co-occurrence of common adolescent pain with anxiety and depression symptoms are very limited. Opioid prescriptions for adolescent pain problems are on t...

Association between bariatric surgery with long-term analgesic prescription and all-cause mortality among patients with osteoarthritis: a general population-based cohort study.

Jul 26, 2021

There is still a large unmet need for novel osteoarthritis (OA) treatments that could provide clinically important effects on long-term pain relief (≥12 months). We examined the relation of bariatri...

Evaluation of the HeroWear Apex back-assist exosuit during multiple brief tasks.

Jul 26, 2021

Trunk exoskeletons are wearable devices that support humans during physically demanding tasks by reducing biomechanical loads on the back. While most trunk exoskeletons are rigid devices, more lightwe...

Endovascular treatment of a ruptured post-traumatic false aneurysm of the aortic isthmus: A case report.

Jul 26, 2021

The false aneurysm of the aortic isthmus is, given its severity and case fatality rate, a subject of interest in vascular surgery. The interest of this article is the analysis of the different charact...

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