Aug 19, 2021

Large placebo responses often negatively affect randomized controlled trials within the pain area. Understanding different possible factors that influence the placebo response is therefore important. ...

Aug 19, 2021

Chronic neuropathic pain (NP) is a common and often debilitating secondary condition for persons with spinal cord injury (SCI) and is minimally responsive to existing pharmacological and nonpharmacolo...

Aug 17, 2021

“Tinnitus is a condition that affects approximately 10% of the adult population in the United States and can diminish one’s quality of life,” explains Hamid R. Djalilian, MD. “To date, there a...

Aug 16, 2021

Individuals who initiate injection drug use often receive assistance from an injection-knowledgeable peer. Persons who assist peers in injection initiation events often inject frequently, which height...

Aug 16, 2021

In this study, a rapid liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the targeted analysis of 98 New Psychoactive Substances (NPS) from the hair...

Aug 16, 2021

One of the common disorders in people with quadriplegia is having a weak grip strength that can affect activities of daily living (ADL). This study presents the design of a soft robotic glove via pneu...

Aug 16, 2021

Altered brain structure and function is evident in adults with multisite chronic pain. Although many such adults trace their pain back to childhood, it has been difficult to disentangle whether centra...

Aug 16, 2021

Concomitant use of pregabalin with opioids and/or benzodiazepines is common, despite the increased risks. However, clinical trials suggest pregabalin can have an opioid-sparing effect when treating ac...

Aug 16, 2021

The Dysfunctional Chronic Pain (Dysfunctional CP) phenotype is an empirically-identifiable CP subtype with unclear pathophysiological mechanisms that cuts across specific medical CP diagnoses. This st...

Aug 12, 2021

“For most patients, pain control remains unsatisfactory,” explains Feng Pan, PhD, MMed, MBBS. “The few pharmacologic analgesic options available have limited efficacy and carry a substantial ris...

Aug 12, 2021

Long-term potentiation (LTP) of synaptic transmission is considered to be a cellular counterpart of learning and memory. Activation of postsynaptic NMDA type glutamate receptor (NMDA-R) induces traffi...

Aug 12, 2021

Spinal cord injury (SCI), as one of the intractable diseases in clinical medicine, is afflicting thousands of human beings, and the pathological changes after the injury have been a hot spot for explo...

Aug 12, 2021

Endogenous pain modulation, as tested by the conditioned pain modulation (CPM) protocol, is typically less efficient in chronic pain patients compared to healthy controls. We aimed to assess whether C...

Aug 09, 2021

Herbal beverages have been used as a natural part of the medicinal and food culture in northwestern Argentina. The flower beverages (infusion or decoction) of Acacia caven, Geoffroea decorticans and L...

Aug 09, 2021

Chronic spinal pain poses complex challenges for healthcare around the world and is in need of effective interventions. Pain Neuroscience Education (PNE) is a promising intervention hypothesized to im...

Aug 08, 2021

“Migraine, which affects more than 1 billion people worldwide, is one of the leading causes of disability in people younger than 50,” says Keisuke Suzuki, MD, PhD. “In addition to moderate-to-se...

Aug 05, 2021

Men with Peyronie’s disease (PD) typically present with complaints of penile deformity, but some patients also report suffering from pain and erectile dysfunction (ED). “There is a common misconc...

Aug 05, 2021

We aimed to identify differences in prescription opioid-related behaviors between adults with and without disabilities in the U.S. We analyzed data from the 2015-2017 National Survey on Drug Use and H...

Aug 05, 2021

Primary headache is a common cause of pediatric emergency department (PED) visits. Without published guidelines to direct treatment options, various strategies lacking evidence are often employed. Thi...

Aug 05, 2021

To explore the effectiveness and safety of 3 oral cannabinoid preparations (FM2®, Bedrocan® and Bediol®) in the treatment of chronic migraine.Retrospective, cohort study.Patients with chronic migra...