Jan 16, 2023

Projections from the periaqueductal gray (PAG) to the rostral ventromedial medulla (RVM) are known to engage in descending pain modulation, but how the neural substrates of the PAG-RVM projections con...

Jan 16, 2023

Systemic lupus erythematosus (SLE) is an unpredictable autoimmune disease where the body's immune system mistakenly attacks healthy tissues in many parts of the body. Chronic pain is one of the most f...

Jan 09, 2023

Substance use disorders (SUDs) are increasing in the obstetric population, vary with demographic characteristics, and are associated with adverse pregnancy outcomes. Cannabis use disorder and opioid u...

Jan 09, 2023

Transcranial alternating current stimulation (tACS) is believed to modulate brain oscillations in a frequency-specific manner. Given the correlation between sensorimotor α-oscillations and pain perce...

Jan 09, 2023

Cognitive bias modification for interpretation (CBM-I) is an effective intervention for anxiety, but there is only a single trial in people with chronic pain. The aim of this randomized controlled tri...

Jan 02, 2023

Ochratoxin A (OTA), a secondary fungal metabolite with nephrotoxicity, is widespread in numerous kinds of feeds and foodstuffs. Ursolic acid (UA), a water-insoluble pentacyclic triterpene acid, exists...

Jan 02, 2023

The aim of this study was to compare the effects of constant rate infusions (CRI) of fentanyl alone or combined with lidocaine and ketamine (FLK), on physiological parameters, isoflurane requirements ...

Jan 02, 2023

This study aimed to evaluate the long-term effects of spinal cord stimulation (SCS) in patients with painful diabetic polyneuropathy (PDPN).This prospective cohort study was the eight-to-ten-year foll...

Jan 02, 2023

Regarding the treatment of ankle arthritis, the choice of arthroscopic ankle arthrodesis (AAA) or open ankle arthrodesis (OAA) remains controversial. To guide clinical decision-making, we conducted a ...

Jan 02, 2023

Resolvin D5 (RvD5) is a specialized pro-resolving lipid mediator with potent anti-inflammatory and analgesic properties. Orofacial pain conditions, especially those that are chronic, present clinical ...

Jan 02, 2023

Venom-derived Na1.7 channel blockers have promising prospects in pain management. The 34-residue tarantula peptide GpTx-1 is a potent Na1.7 channel blocker. Its powerful analog [Ala, Phe, Leu, Arg]GpT...

Dec 20, 2022

The following is a summary of "Psychometric Evaluation of the Veterans Affairs Bereaved Family Survey in Community Nursing Homes" published in the December 2022 issue of Pain and Symptom Management by...

Dec 20, 2022

The following is a summary of "Video and In-Person Palliative Care Delivery Challenges before and during the COVID-19 Pandemic" published in the December 2022 issue of Pain and Symptom Management by C...

Dec 20, 2022

The following is a summary of "Prognostic Understanding and Goals of Palliative Radiotherapy: A Qualitative Study" published in the December 2022 issue of Pain and Symptom Management by Chen et al. ...

Dec 19, 2022

Medicinal cannabis (MC) products have been available on prescription in Australia for around six years. General practitioners (GPs) are at the forefront of MC prescribing and recent years have seen su...

Dec 19, 2022

The aim of the study was to compare psychological characteristics of adolescent patients with Juvenile Fibromyalgia Syndrome (JFM) with individuals suffering from chronic pain (CP) due to headache or ...

Dec 19, 2022

Neuropathic pain is a refractory pain state, and its mechanism is still not clear. Previous studies have shown that the purine receptor P2X4R expressed on hyperactive microglia in the spinal cord is e...

Dec 19, 2022

The association between osteoporosis, a common metabolic bone disorder, and atherosclerosis has been reported in different studies. In this study, we aimed to investigate the association between the c...

Dec 19, 2022

Large-scale genome-wide association studies (GWAS) have been successfully applied to a wide range of genetic variants underlying complex diseases. The network-based regression approach has been develo...

Dec 19, 2022

Patients with chronic pain show large placebo effects in clinical trials, and inert pills can lead to clinically meaningful analgesia that can last from days to weeks. Whether the placebo response can...