Pain General
Jan 30, 2020
Primary pulmonary MALT (mucosa-associated lymphoid tissue) lymphoma is a rare entity that imposes a rigorous and demanding diagnostic work-up.We present the case of a 74-year-old female non-smoker wit...
Jan 30, 2020
To reevaluate the frequency and pattern of complementary and integrative medicine (CIM) use in patients with fibromyalgia (FM).Consecutive patients with FM who were referred to the Mayo Clinic fibromy...
Jan 30, 2020
Abatacept may exert its clinical effect on rheumatoid arthritis (RA) by suppressing anti-cyclic citrullinated peptide (CCP) antibody production. This study was undertaken to test this hypothesis by ex...
Jan 30, 2020
Post-stroke Complex Regional Pain Syndrome (CRPS) is characterized by swelling, pain and changes in the skin that appear on the affected wrist and hand. In this retrospective study, we analyzed the re...
Jan 30, 2020
The use of long-term opioid therapy for chronic pain remains common, yet data on long-term outcomes, especially after dose escalation, are sparse. This study examined potential benefits and harms asso...
Jan 30, 2020
Non-invasive measures of neuroinflammatory processes in humans could substantially aid diagnosis and therapeutic development for many disorders, including chronic pain. Several proton Magnetic Resonan...
Jan 27, 2020
Knowledge of factors involved in the associations between pain, common mental disorders and future work incapacity is still scarce. The aim of this study was to examine the overlap between genetic and...
Jan 27, 2020
Mechanical allodynia is a cardinal sign of several inflammatory pain disorders where Nerve Growth Factor, a prototypic neurotrophin, plays a crucial role by binding to TrkA receptors. Here, we took th...
Jan 27, 2020
Neck pain and headache are two of the most common complications of whiplash injury. Therefore, we performed a systematic literature search on PubMed and Embase for publications reporting on the preval...
Jan 27, 2020
Sodium channel Nav1.7, encoded by the SCN9A gene, is a well validated target that plays a key role in controlling pain sensation. Loss-of-function mutations of Nav1.7 can cause a syndrome of profound ...
Jan 27, 2020
Endogenous pain inhibition is less efficient in chronic pain patients. Diffuse noxious inhibitory control (DNIC), a form of endogenous pain inhibition, is compromised in women and older people, making...
Jan 24, 2020
For patients with painful chronic pancreatitis, surgical treatment is postponed until medical and endoscopic treatment have failed. Observational studies have suggested that earlier surgery could miti...
Jan 22, 2020
There has been a rise in many forms of science-rejection, ranging from vaccine hesitancy and refusal, antithesis to research investment, and legislation that would encourage factual-relativism. Unless...
Jan 21, 2020
TUESDAY, Jan. 21, 2020 (HealthDay News) -- The first U.S. case of a new coronavirus illness that originated in central China has been identified in a patient in Washington State, federal health of...
Jan 17, 2020
Chemotherapy-induced neuropathic pain is a serious adverse effect of chemotherapeutic agents. Clinical evidence suggests that stress is a risk factor for development and/or worsening of chemotherapy-i...
Jan 17, 2020
Increasing numbers survive cancers in childhood and adolescence. Long-term survivors of cancers in adulthood have increased prevalence of pain and consumption of analgesics. It is not established whet...
Jan 17, 2020
Alleviating chronic pain is challenging, due to lack of drugs that effectively inhibit nociceptors without off target effects on motor or central neurons. Dorsal root ganglia (DRG) contain nociceptive...
Jan 17, 2020
Race disparities in pain care are well-documented. Given that the majority of Black patients are treated by White providers, patient-provider racial discordance is one hypothesized contributor to thes...
Jan 17, 2020
Patellofemoral pain (PFP) is a common complaint among young sports active adolescents. This study evaluated the longitudinal changes in pro-nociceptive and anti-nociceptive mechanisms in young adolesc...
Jan 08, 2020
Significantly more patients treated with Ubrelvy versus placebo achieved pain freedom two hours post-treatment TUESDAY, Dec. 24, 2019 (HealthDay News) -- Ubrelvy (ubrogepant) tablets have been ap...