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Pain General

Acute ostracism-related pain sensitization in the context of accumulated lifetime experiences of ostracism.

Feb 27, 2023

Ostracism (i.e., being ignored/ excluded) is a form of social adversity that powerfully impacts health and well-being. While laboratory research indicates that experimentally manipulated experiences o...

Cervical spine injuries in spinal ankylosing disorders: results of single-stage posterior stabilization without posterolateral fusion.

Feb 20, 2023

Patients with long-segment cervical spinal fusion resulting from spinal ankylosing disorders (SADs) are at high risk for highly unstable cervical spine fractures necessitating surgery as the treatment...

The roles of periaqueductal gray and dorsal raphe nucleus dopaminergic systems in the mechanisms of thermal hypersensitivity and depression in mice.

Feb 20, 2023

Depression and thermal hypersensitivity share pathogenic features and symptomology, but their pathophysiologic interactions have not been fully eluidated. Dopaminergic systems in the ventrolateral per...

Fecal microbiota transplantation revealed a pain-related gut microbiota community in ovariectomized mice.

Feb 20, 2023

Higher sensitivity to pain is a common clinical symptom in postmenopausal females. The gut microbiota (GM) has recently been identified as participating in various pathophysiological processes and may...

Transversus abdominis plane block in adult open liver surgery patients: A systematic review with meta-analysis of randomized controlled trials.

Feb 13, 2023

The objective of this meta-analysis is to evaluate the efficacy of Transversus Abdominis Plane Block (TAPB) in pain control and recovery after open hepatic surgery.We searched for the articles in PubM...

An investigation of the effects of connective tissue massage in women with migraine: A controlled clinical trial.

Feb 13, 2023

To investigate the effects of connective tissue massage (CTM) on pain characteristics, accompanying symptoms, medication usage, disability, sleep quality, psychological status, and quality of life in ...

Treating fibromyalgia with electrical neuromodulation: A systematic review and meta-analysis.

Feb 13, 2023

Several types of electrical neuromodulation (such as transcranial direct current stimulation, tDCS; transcutaneous electrical nerve stimulation) have been applied in the treatment of fibromyalgia. The...

Current attitudes toward carrier screening for spinal muscular atrophy among pregnant women in Eastern China.

Feb 13, 2023

Spinal muscular atrophy (SMA) is an autosomal recessive and often fatal neurological disease. However, very little is known about the attitudes toward SMA carrier screening among Chinese pregnant peop...

WISP-2 modulates the induction of inflammatory mediators and cartilage catabolism in chondrocytes.

Feb 13, 2023

Wnt-1 inducible signaling pathway protein 2 (WISP-2/CCN5) is a recently identified adipokine that has been described as an important mediator of canonical Wnt activation in adipogenic precursor cells....

Childhood-Onset Lupus Nephritis in the Childhood Arthritis and Rheumatology Research Alliance Registry: Short-Term Kidney Status and Variation in Care.

Feb 13, 2023

The goal was to characterize short-term kidney status and describe variation in early care utilization in a multicenter cohort of patients with childhood-onset systemic lupus erythematosus (cSLE) and ...

Positive childhood experiences and chronic pain among children and adolescents in the United States.

Feb 13, 2023

Positive childhood experiences (PCEs) are associated with better mental and physical health outcomes and moderate the negative effects of adverse childhood experiences (ACEs). However, knowledge of th...

Long-acting opioids and cardiovascular diseases: Help or hindrance!

Feb 06, 2023

Opioids are widely being used for chronic pain management, cough and diarrhea suppressants, anesthetic agents, and opioid de-addiction therapy. Opioid receptors, present in the central nervous system ...

[Chinese recommendations for the management of fibromyalgia syndrome].

Feb 06, 2023

Fibromyalgia syndrome (FMS) is a common clinical syndrome. At present, the lack of epidemiological data from large-sample studies in our country persists, and there are many difficulties in diagnosis ...

Corticospinal and spinal adaptations following lower limb motor skill training: a meta-analysis with best evidence synthesis.

Feb 06, 2023

Motor skill training alters the human nervous system; however, lower limb motor tasks have been less researched compared to upper limb tasks. This meta-analysis with best evidence synthesis aimed to d...

Overweight increases perioperative spinal surgery complications: a single-center retrospective study.

Feb 06, 2023

The World Health Organization (WHO) defines a person with a body mass index (BMI) greater than or equal to 25 kg/m as overweight. Being overweight is a lifestyle-related disease; however, little is k...

BML-111 inhibits osteoclast differentiation by suppressing the MAPK and NF-κB pathways, alleviating deterioration of the knee joints in a CIA rat model.

Feb 06, 2023

Irreversible destruction of joints is the hallmark of rheumatoid arthritis (RA). Osteoclasts are the only bone-resorbing cells and play an important role in joint rebuilding. BML-111 (5(S),6(R),7-trih...

Subacromial Balloon Spacer for Massive Irreparable Rotator Cuff Tears.

Feb 06, 2023

Massive irreparable rotator cuff tears (MIRCTs) represent 10% to 40% of cases of rotator cuff abnormality and are challenging to treat. When MIRCTs are unresponsive to nonoperative treatment, surgery ...

NEUROMUSCULAR ADAPTATIONS TO EXPERIMENTALLY INDUCED PAIN IN THE LUMBAR REGION: SYSTEMATIC REVIEW AND META-ANALYSIS.

Feb 06, 2023

Experimental pain models are frequently used to understand the influence of pain on the control of human movement. In this systematic review, we assessed the effects of experimentally induced pain in ...

Polygenic Contributions to Chronic Overlapping Pain Conditions in a Large Electronic Health Record Sample.

Feb 06, 2023

Chronic overlapping pain conditions (COPCs) are believed to share common etiological mechanisms involving central sensitization. Genetic and environmental factors putatively combine to influence susce...

The incidence of new mental health disorders after acute pancreatitis: A large, propensity-matched, observational study.

Jan 30, 2023

The prevalence of acute pancreatitis (AP) and mental health disorders (MHDs) are rising. While the association between chronic pancreatitis (CP) and MHDs is established, it is unknown whether there is...

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