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Orthopedics

Osteoidosis leads to altered differentiation and function of osteoclasts.

Apr 14, 2020

In patients with osteomalacia, a defect in bone mineralization leads to changed characteristics of the bone surface. Considering that the properties of the surrounding matrix influence function and di...

Mesenchymal stem cells alleviate rat diabetic nephropathy by suppressing CD103 DCs-mediated CD8 T cell responses.

Apr 14, 2020

Diabetic nephropathy (DN) as a kind of serious microvascular complication of Diabetes Mellitus (DM) usually causes the end-stage of renal disease (ESRD). Studies have demonstrated that CD103 dendritic...

Polyetheretherketone Versus Titanium Cages for Posterior Lumbar Interbody Fusion: Meta-Analysis and Review of the Literature.

Apr 07, 2020

Lumbar fusion with implantation of interbody cage is a common procedure for treatment of lumbar degenerative disease. This study aims to compare the fusion and subsidence rates of titanium (Ti) versus...

The Influence of Mechanic Factors in Disc Degeneration Disease as a Determinant for Surgical Indication.

Apr 07, 2020

Low back pain is the most common reason for physician visit in Western population. It's one of the factors that affect health-related quality of life. Intervertebral disc degeneration is one of the le...

Reinforcing interpenetrating network hydrogels with 3D printed polymer networks to engineer cartilage mimetic composites.

Apr 07, 2020

Engineering constructs that mimic the complex structure, composition and biomechanics of the articular cartilage represents a promising route to joint regeneration. Such tissue engineering strategies ...

Modulation of bone formation and resorption using a novel ZOL loaded gelatin NPs integrated porous titanium scaffold: An in vitro and in vivo study.

Apr 07, 2020

Osteoporotic bone defect is a major challenge in clinics for bone regeneration. Under the condition of osteoporosis, excessive bone absorption and impaired osteogenesis resulted in unexpected long hea...

A generalized system of tissue-mimicking materials for computed tomography (CT) and magnetic resonance imaging (MRI).

Apr 07, 2020

The advent of technologies such as magnetic resonance imaging (MRI)-guided radiation therapy has led to the need for phantom materials that are capable of producing tissue-like contrast on both MRI an...

Tissue sodium concentrations in chronic kidney disease and dialysis patients by lower leg sodium-23 magnetic resonance imaging.

Apr 07, 2020

Sodium-23 magnetic resonance imaging (23Na MRI) allows direct measurement of tissue sodium concentrations. Current knowledge of skin, muscle and bone sodium concentrations in chronic kidney disease (C...

Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype.

Apr 07, 2020

Spinal fusion surgery is a common treatment modality for various pathologic conditions of the spine. The bone morphogenetic protein 2 (BMP2) analogue L51P acts as a general inhibitor of BMP antagonist...

Increased prevalence of self-reported fractures in Asian Indians with diabetes: Results from the ICMR-INDIAB population based cross-sectional study.

Mar 23, 2020

Diabetes mellitus (DM), has been associated with increased fracture risk. However, there are no data pertaining to the prevalence of fractures for patients with DM in India. The aim of this study was ...

The Impact of the Lordosis Distribution Index on Failure after Surgical Treatment of Adult Spinal Deformity.

Mar 23, 2020

Proximal junctional failure (PFJ) is a common and dreaded complication of adult spinal deformity. Previous research has identified parameters associated with the development of PJF and the search for ...

Perceptions of risk for stress fractures: A qualitative study of female runners with and without stress fracture histories.

Mar 23, 2020

To gain insight into perceived factors related to bone health and stress fracture (SF) prevention for female runners and to understand their experiences within the medical community.Cohort qualitative...

Experimental study on the mechanical properties of biological hydrogels of different concentrations.

Mar 23, 2020

Biological hydrogels provide a conducive three-dimensional extracellular matrix environment for encapsulating and cultivating living cells. Microenvironmental modulus of hydrogels dictates several cha...

Relationship between skin and urine colonization and surgical site infection in the proximal femur fracture: a prospective study.

Mar 23, 2020

Antibiotic prophylaxis is routinely used in the surgical management of proximal femur fractures. The role of bacterial colonization of the skin and urine in the development of deep surgical site infec...

Influence of estradiol treatment on bone marrow cell differentiation in collagenase-induced arthritis.

Mar 23, 2020

Estrogen is one of the important regulators of the balance between bone formation and bone resorption that can modulate the levels and activity of certain growth factors and cytokines. In this study, ...

A comprehensive analysis to understand the mechanism of action of balneotherapy: why, how, and where they can be used? Evidence from in vitro studies performed on human and animal samples.

Mar 23, 2020

Balneotherapy (BT) is one of the most commonly used complementary therapies for many pathological conditions. Its beneficial effects are related to physical and chemical factors, but the exact mechani...

Increased Exhaustion of the Subchondral Bone-Derived Mesenchymal Stem/ Stromal Cells in Primary Versus Dysplastic Osteoarthritis.

Mar 23, 2020

Mesenchymal stem/ stromal cell (MSC) exhaustion has been suggested to be a hallmark of aging. Osteoarthritis has a complex etiology that comprises several factors. Dysplasia has been shown to be an i...

Neuropeptide Y knockdown in the dorsomedial hypothalamus improved basal and obesity-induced decrease in bone mass density.

Mar 23, 2020

Neuropeptide Y (NPY) has been shown to have a prominent role in the control of bone formation through the regulation of osteoblast activity. We aimed to investigate the role of hypothalamus-derived NP...

Systematic DOACs oral anticoagulation in patients with atrial fibrillation and chronic kidney disease: the nephrologist's perspective.

Mar 23, 2020

Atrial fibrillation (AF) is highly prevalent among patients with chronic kidney disease (CKD), and also associated with unfavorable outcome. Anticoagulant therapy is the mainstep of management in such...

Effect of Box Height on Box Jump Performance in Elite Female Handball Players.

Mar 19, 2020

Koefoed, N, Dam, S, and Kersting, UG. Effect of box height on box jump performance in elite female team handball players. J Strength Cond Res XX(X): 000-000, 2020-This study aimed at investigating whe...

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