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Orthopedics

Tilianin attenuates HDM-induced allergic asthma by suppressing Th2-immune responses via downregulation of IRF4 in dendritic cells.

Oct 29, 2020

Acacetin 7-O-β-D-glucoside (tilianin) is a major constituent of Agastache rugosa, a traditional medicine that has long been used for the treatment of gastrointestinal disorders. Tilianin has a wide v...

Model-based dual-energy tomographic image reconstruction of objects containing known metal components.

Oct 29, 2020

Dual-energy (DE) decomposition has been adopted in orthopedic imaging to measure bone composition and visualize intraarticular contrast enhancement. One of the potential applications involves monitori...

Trabecular Bone is Increased in a Rat Model of Polycystic Ovary Syndrome.

Oct 29, 2020

Polycystic ovary syndrome (PCOS) in an intricate disorder characterized by reproductive and metabolic abnormalities that may affect bone quality and strength along with the lifespan. The present study...

COVID-19 Pandemic Challenges Osteoporosis Management

Oct 27, 2020

MONDAY, Oct. 26, 2020 (HealthDay News) -- The COVID-19 pandemic may have negatively impacted osteoporosis management, according to a study published online Oct. 14 in Osteoporosis International. Eu...

MRI Safe for Those With Non-MRI-Conditional Cardiac Devices

Oct 26, 2020

FRIDAY, Oct. 23, 2020 (HealthDay News) -- Magnetic resonance imaging (MRI) can be safely performed in patients with non-MRI-conditional cardiac devices, including pacemakers and abandoned leads, accor...

SHEA Updates Guidance for Health Care Staff With Hepatitis, HIV

Oct 26, 2020

FRIDAY, Oct. 23, 2020 (HealthDay News) -- In a Society for Healthcare Epidemiology of America white paper, published online Oct. 14 in Infection Control & Hospital Epidemiology, updated recommenda...

American College of Surgeons, Oct. 3-7

Oct 26, 2020

The 105th Annual American College of Surgeons Clinical Congress The annual meeting of the American College of Surgeons was held virtually this year from Oct. 3 to 7 and attracted participants from a...

Screw-in-screw fixation of fragility sacrum fracturesprovides high stability without loosening - Biomechanicalevaluation of a new concept.

Oct 26, 2020

Surgical treatment of fragility sacrum fractureswith percutaneous sacroiliac (SI) screw fixation is associated with high failure rates. Turn-out is detected in up to 20% of the patients. The aim of th...

Prevalence of sports-related spinal injury stratified by competition level and return to play guidelines.

Oct 26, 2020

Spinal injury is among the most severe and feared injuries an athlete may face. We present an up-to-date review of the recent literature, stratifying recommendations based on injury location (cervical...

Effectiveness of Photobiomodulation as an Adjunct to Non-surgical Periodontal Therapy in the Management of Periodontitis- A Systematic Review of in vivo Human Studies.

Oct 26, 2020

Photobiomodulation therapy (PBMT) has anti-inflammatory, analgesic and regenerative properties. This systematic review aimed to critically appraise the published data of in vivo human randomized clini...

Clinical utilization of blinatumomab and inotuzumab immunotherapy in children with relapsed or refractory B-acute lymphoblastic leukemia.

Oct 26, 2020

The treatment paradigm for patients with relapsed/refractory B-cell acute lymphoblastic leukemia (rrALL) has been revolutionized given recent clinical trials demonstrating remarkable success of immuno...

European Consensus Statement on the diagnosis and management of osteoporosis in chronic kidney disease stages G4-G5D.

Oct 26, 2020

Controlling the excessive fracture burden in patients with chronic kidney disease (CKD) Stages G4-G5D remains an impressive challenge. The reasons are 2-fold. First, the pathophysiology of bone fragil...

Low dose IL-2 suppress osteoclastogenesis in collagen-induced arthritis via JNK dependent pathway.

Oct 26, 2020

Rheumatoid arthritis (RA) is one of the most common chronic immune joint diseases, mainly involving blood vessels and small joints. The complex pathogenesis of RA greatly increases the difficulty of t...

Corticosteroid Exposure Affects Bone Health in Asthma Patients

Oct 23, 2020

WEDNESDAY, Oct. 21, 2020 (HealthDay News) -- For patients with asthma, oral corticosteroid (OCS) and inhaled corticosteroid (ICS) use is associated with an increased risk for osteoporosis and fragilit...

Total Joint Arthroplasty Linked to Reduced Risk for Falls

Oct 22, 2020

WEDNESDAY, Oct. 21, 2020 (HealthDay News) -- For patients with a primary diagnosis of hip or knee osteoarthritis (OA), total joint arthroplasty (TJA) is associated with a reduced risk for traumatic fa...

Greater Conditioned Pain Modulation Is Associated With Enhanced Morphine Analgesia in Healthy Individuals and Patients with Chronic Low Back Pain.

Oct 22, 2020

Conditioned pain modulation (CPM) protocols index magnitude of descending pain inhibition. This study evaluated whether degree of CPM, controlling for CPM expectancy confounds, was associated with ana...

Tooth Development Following Mandibular Distraction Osteogenesis in Neonates With Pierre Robin Sequence.

Oct 22, 2020

Mandibular distraction osteogenesis is a widely utilized surgical procedure in the pediatric population for the treatment of mandibular retrognathia. Patients with congenital abnormalities may display...

Variable Fixation Technology Provides Rigid as Well as Progressive Dynamic Fixation: A Biomechanical Investigation.

Oct 22, 2020

A new locking-screw technology, the Variable Fixation Locking Screw (VFLS; Biomech Innovations), was developed with the aim of promoting secondary fracture-healing. The VFLS features a resorbable slee...

An Assessment of Randomized Controlled Trial Quality in The Journal of Bone & Joint Surgery: Update from 2001 to 2013.

Oct 22, 2020

The quality of reporting of randomized controlled trials (RCTs) published in The Journal of Bone & Joint Surgery (JBJS) from 1988 to 2000 was previously analyzed. The purpose of this current study...

Publishing Characteristics of Foot and Ankle Research Over a 15-Year Time Interval: A Review of The Journal of Bone & Joint Surgery from 2004 to 2018.

Oct 22, 2020

As the foot and ankle subspecialty continues to grow in orthopaedics, trends in published literature provide valuable insights to help understand and strengthen the field. The current study evaluates ...

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