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Orthopedics General

TNF alpha promotes clonal dominance of KIT D816V+ cells in mastocytosis: role of survivin and impact on prognosis.

Dec 25, 2023

Systemic mastocytosis (SM) is defined by expansion and accumulation of neoplastic mast cells (MC) in the bone marrow (BM) and extracutaneous organs. Most patients harbor a somatic KIT D816V mutation, ...

Quality of life in sarcopenia measured with the SarQoL questionnaire: A meta-analysis of individual patient data.

Dec 25, 2023

Age-related sarcopenia, resulting from a gradual loss in skeletal muscle mass and strength, is pivotal to the increased prevalence of functional limitation among the older adult community. The purpose...

Sclerosing epithelioid fibrosarcoma associated with WRN gene variant presenting as chronic dyspnea and pathologic cervical fracture: a case report and review of the literature.

Dec 18, 2023

Sclerosing epithelioid fibrosarcoma is an aggressive sarcoma subtype with poor prognosis and limited response to conventional chemotherapy regimens. Diagnosis can be difficult owing to its variable pr...

Deformation mechanisms and Surface/Interface characteristics of titanium-based thermoplastic FMLs under ultrasonic impact loading.

Dec 18, 2023

Some typical defects like delamination, fiber fracture, non-uniform resin distribution and springback are inevitable as titanium-based thermoplastic FMLs are formed by general stamping process at elev...

The long head of the biceps tendon undergoes multiaxial deformation during shoulder motion.

Dec 18, 2023

The long head biceps tendon (LHBT) is presumed a common source of shoulder joint pain and injury. Despite common LHBT pathologies, diagnosis and preferred treatment remain frequently debated. This Sho...

A digital male pelvis phantom series showing anatomical variations over the course of fractionated radiotherapy treatment.

Dec 11, 2023

Daily IGRT images show day-to-day anatomical variations in patients undergoing fractionated prostate radiotherapy. This is of particular importance in particle beam treatments.To develop a digital pha...

Compared to what? An analysis of comparators in trials informing the National Institute of Clinical Excellence (NICE) low back pain guideline.

Nov 20, 2023

Low back pain (LBP) is the leading cause of disability globally. Clinical practice guidelines (CPGs) have been developed in hopes of encouraging evidence-based care for LBP. However, poor quality of t...

Risk Factors for Failure of Nonsurgical Management of Ulnar Shaft Fractures.

Nov 13, 2023

Isolated ulnar shaft fractures are frequently managed nonsurgically. However, rates of nonsurgical treatment failure remain substantial, and risk factors for the failure of nonsurgical management are ...

Avulsion fracture is associated with more pain after anatomic repair procedure for ATFL injury at the talar side.

Nov 13, 2023

To evaluate the clinical outcomes of anatomic repair procedure for chronic anterior talofibular ligament (ATFL) injury at the talar side, and to compare the outcomes between patients with and without ...

Synthesis and in vitro characteristics of biogenic-derived hydroxyapatite for bone remodeling applications.

Nov 13, 2023

The inorganic component of bone matrix, hydroxyapatite (HAp) (with formula Ca(PO)(OH)), can be obtained from inexpensive waste resources that serve as excellent calcium precursors. In the present stud...

Surgical outcomes of acetabular fracture of elderly patients with superomedial dome impaction.

Nov 06, 2023

This study aimed to investigate the outcomes of elderly acetabular fractures according to the reduction of impacted dome fragments. A retrospective cohort study was performed in two institutions. Fift...

Sex-specific diagnostic efficacy of MRI in axial spondyloarthritis: challenging the 'One Size Fits All' notion.

Oct 30, 2023

Sex-specific differences in the presentation of axial spondyloarthritis (axSpA) may contribute to a diagnostic delay in women. The aim of this study was to investigate the diagnostic performance of MR...

Best of Both Worlds? Fixation of Distal Femur Fractures with the Nail-Plate Construct.

Oct 23, 2023

Distal femoral fractures are a significant injury sustained by low- and high-energy trauma. Common treatment practices are lateral locking plate or intramedullary nail fixation, with disadvantages inc...

Editorial Commentary: Tunnel Widening and Loss of Reduction May Be Inevitable After Acromioclavicular Stabilization With Cortical Suspensory Devices Whether Inset (Top Hats) or Onlay (Buttons).

Oct 23, 2023

Despite widely varying techniques, coracoclavicular (CC) stabilization after traumatic, unstable acromioclavicular (AC) joint dislocations shows notable rates of perioperative complications, radiograp...

Rip-Stop Fixation Constructs for Rotator Cuff Repair.

Oct 23, 2023

In arthroscopic rotator cuff repair, poor tendon quality, medially based tears, lateral tendon loss, or limited tendon mobility can all preclude the use of double-row suture constructs, presenting a c...

Surgical Treatment for Isolated Closed Multi-Metatarsal Fractures: At Least 2-Year Outcomes in 79 Feet.

Oct 16, 2023

Multi-metatarsal fractures are a particular type possibly associated with worse functional outcomes. Existing studies are scarce, fragmented, and lack control for confounders. This study aimed to expl...

Occurrence and prediction of flare after tapering of TNF inhibitors in patients with axial spondyloarthritis.

Oct 16, 2023

Patients with axial spondyloarthritis (axSpA) in clinical remission tapered Tumor Necrosis Factor inhibitor (TNFi) therapy according to a clinical guideline. During 2-years' follow-up, we aimed to inv...

Satisfactory medium- to long-term outcomes of cemented rotating hinge prosthesis in revision total knee arthroplasty.

Oct 16, 2023

The aim of this study was to evaluate medium- to long-term outcomes and complications of the Stanmore Modular Individualised Lower Extremity System (SMILES) rotating hinge implant in revision total kn...

Comparison of the effectiveness of piezocision-aided canine retraction augmented with micro-osteoperforation: a randomized controlled trial.

Oct 16, 2023

To evaluate the effectiveness of micro-osteoperforation (MOP) on the rate of piezocision-aided canine retraction (CR).The split-mouth study included 25 participants at the stage of commencing CR. The ...

Quadriceps Tendon and Bone-Patellar-Tendon-Bone Autograft ACL Reconstructions Have Similar Post-Operative Quadriceps Limb Symmetry Index.

Oct 09, 2023

To compare postoperative isometric quadriceps strength indices (QI%) and hamstring strength limb symmetry indices (HI%) between partial thickness quadriceps tendon (pQT), full thickness quadriceps ten...

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