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Orthopedics General

Ruxolitinib rechallenge in resistant or intolerant patients with myelofibrosis: Frequency, therapeutic effects, and impact on outcome.

Apr 05, 2021

After ruxolitinib discontinuation, the outcome of patients with myelofibrosis (MF) is poor with scarce therapeutic possibilities.The authors performed a subanalysis of an observational, retrospective ...

Musculoskeletal Health in Premature Ovarian Insufficiency. Part Two: Bone.

Apr 01, 2021

Accelerated bone loss and muscle loss coexist in women with premature ovarian insufficiency (POI), but there are significant gaps in our understanding of musculoskeletal health in POI. This review des...

A Comparative Mechanical Study of Two Types of Femur Bone Implant Using the Finite Element Method.

Mar 29, 2021

The femoral bone fracture is one of the most common fractures that orthopedic surgeons deal with. These fractures are associated with a significant percentage of death due to non-orthopedic complicati...

Biodegradable cement augmentation of gamma nail osteosynthesis reduces migration in pertrochanteric fractures, a biomechanical in vitro study.

Mar 29, 2021

Cut-out of gamma nail often results from poor primary bone stability, suboptimal reduction (varus) and excentric placement of the head element which may lead to "instability" and frequently requires r...

Synthesis and evaluation of magnesium/co-precipitated hydroxyapatite based composite for biomedical application.

Mar 29, 2021

Owing to its inductive attributes, hydroxyapatite is an ideal reinforcement to tailor the degradation kinetics of magnesium-based temporary orthopedic implants. However, the large difference in the me...

Effects of printing path and material components on mechanical properties of 3D-printed polyether-ether-ketone/hydroxyapatite composites.

Mar 29, 2021

Polyether-ether-ketone (PEEK) exhibits excellent mechanical properties and biocompatibility. Three-dimensional (3D) printing of PEEK bone substitutes has been widely used in clinical application. Howe...

Time Course of Neuromuscular, Hormonal, and Perceptual Responses Following Moderate- and High-Load Resistance Priming Exercise.

Mar 25, 2021

The aim of this study was to map responses over 32 hours following high-load (HL) and moderate-load (ML) half-squat priming.Fifteen participants completed control, HL (87% 1RM), and ML (65% 1RM) activ...

The Effect of Attending Physical Rehabilitation After the First Acute Lateral Ankle Sprain on Static Postural Control in Patients With Chronic Ankle Instability.

Mar 25, 2021

Static postural control deficits are commonly documented among individuals with chronic ankle instability (CAI). Evidence suggests individuals with CAI who seek medical attention after an ankle sprain...

Hyperbaric oxygen treatment in recurrent development of complex regional pain syndrome: A case report.

Mar 25, 2021

A broad spectrum of conditions including neuropathic pain, complex regional pain syndrome (CRPS) and fibromyalgia, have been implicated as causes of chronic pain. There is a need for new and effective...

Operationalizing Treat-to-Target for Osteoporosis.

Mar 25, 2021

Treat-to-target (TTT) for osteoporosis is a concept for individualizing patient treatment decisions that focuses on achieving an acceptable level of fracture risk rather than response to treatment alo...

Comparative microcomputed tomographic structural analysis of the trabecular and cortical bone architecture of radius and ulna in toy dog breeds.

Mar 25, 2021

Radius and ulna fractures can be detected in dogs with an incidence of 18.0% and occur more frequently in toy breeds with increased complication rates. The reasons for the predisposition and the incre...

Multiscale porosity in 3D printed gellan-gelatin composite for bone tissue engineering.

Mar 25, 2021

To develop a gelatin-gellan composite scaffold of complex shapes having multiscale porosity using a combination of cryogenic 3D printing and lyophilization for bone tissue engineering.Cryogenic 3D pri...

The degree of correction in open-wedge high tibial osteotomy compromises bone healing: A consecutive review of 101 cases.

Mar 22, 2021

The bone healing in open-wedge high tibial osteotomy (OWHTO) proceeds gradually by a filling of the osteotomy gap. This can comprise several risk factors.A retrospective study analysed the clinical an...

The reliability of rehabilitative ultrasound to measure lateral abdominal muscle thickness: A systematic review and meta-analysis.

Mar 22, 2021

Variations in rehabilitative ultrasound imaging (RUSI) protocols may alter lateral abdominal muscle (LAM) thickness measurements. A standardised protocol is required for clinicians to accurately compa...

Icariin stimulates osteogenesis and suppresses adipogenesis of human bone mesenchymal stem cells via miR-23a-mediated activation of the Wnt/β-catenin signaling pathway.

Mar 22, 2021

Icariin (ICA) is a bioactive compound isolated from epimedium-derived flavonoids that modulates bone mesenchymal stem cell osteogenesis and adipogenesis. However, its precise mechanism in this process...

Electrosprayed calcium silicate nanoparticle-coated titanium implant with improved antibacterial activity and osteogenesis.

Mar 22, 2021

To ensure clinical success, the implant and the surrounding bone tissue must not only be integrated, but also must not be suspected of infection. In this work, an antibacterial and bioactive nanostruc...

Brucellosis in Transplant Recipients: A Systematic Review.

Mar 22, 2021

Brucellosis, a bacterial disease caused by Brucella species. The purpose of this study was to evaluate brucellosis in all types of transplant patients.All the cases of brucellosis in transplant patien...

Trabecular bone score in women with differentiated thyroid cancer on long-term TSH-suppressive therapy.

Mar 18, 2021

Thyrotropin stimulating hormone (TSH) suppression in patients with differentiated thyroid cancer (DTC) aims to decrease the growth and proliferation of thyroid cancer cells. However, the effect of TSH...

Spine and pelvis coordination variability in rowers with and without chronic low back pain during rowing.

Mar 18, 2021

The aim of this study was to compare the spine-pelvis coordination and coordination variability (CV) during rowing in elite rowers with and without chronic low back pain (CLBP). Fourteen professional ...

Postcranial Skeletal Pneumaticity in Cuculidae.

Mar 18, 2021

Postcranial skeletal pneumaticity (i.e., epithelial-lined, air-filled bones) is a condition unique to birds among extant tetrapods. Previous research reveals extensive variation in the expression of t...

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