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Orthopedics General

In vitro-virtual-reality: an anatomically explicit musculoskeletal simulation powered by in vitro muscle using closed loop tissue-software interaction.

May 20, 2021

Muscle force-length dynamics are governed by intrinsic contractile properties, motor stimulation and mechanical load. Although intrinsic properties are well-characterised, physiologists lack in vitro ...

Walking on chains: the morphology and mechanics behind the fin ray derived limbs of sea-robins.

May 20, 2021

Fish fin rays (lepidotrichia) are typically composed of paired and segmented flexible structures (hemitrichia) that help support and change the shape of the fins to affect water flow. Yet, marine ray-...

Different fuel regulation in two types of myofiber results in different antioxidant strategies in Daurian ground squirrels (Spermophilus dauricus) during hibernation.

May 20, 2021

We previously showed that different skeletal muscles in Daurian ground squirrels (Spermophilus dauricus) possess different antioxidant strategies during hibernation; however, the reason for these vari...

Seismic sensitivity and bone conduction mechanisms enable extratympanic hearing in salamanders.

May 20, 2021

The tympanic middle ear is an adaptive sensory novelty that evolved multiple times in all of the major terrestrial tetrapod groups to overcome the impedance mismatch generated when aerial sound encoun...

Galeazzi fracture-dislocations: Long-term prognosis of the distal radioulnar joint.

May 17, 2021

The aim of the present study was to evaluate long-term functional and radiographic outcome in the distal radioulnar joint (DRUJ) for Galeazzi fracture-dislocation after anatomic reduction and rigid fi...

Characteristics of lumbar flexion rhythm at different arm positions.

May 17, 2021

The lumbar spine displays its greatest mobility in ventral flexion, which is a potential risk factor for low back pain. The relative contribution of each segment to the complete flexion is denoted the...

Delay in Hip Fracture Repair in the Elderly: A Missed Opportunity Towards Achieving Better Outcomes.

May 17, 2021

Hip fractures are a major cause of morbidity and mortality in the elderly. The American Academy of Orthopedic Surgeons (AAOS) recommends surgical repair within 48 hours of admission, as this is associ...

Universal Engraftment after Allogeneic Hematopoietic Cell Transplantation Using Cryopreserved CD34 Selected Grafts.

May 17, 2021

As a result of the COVID-19 pandemic, most centers performing allogeneic hematopoietic cell transplant (allo-HCT) have switched to the use of cryopreserved grafts. Previous investigators have suggeste...

Timing of stress fracture in soldiers during the first 6 career months: a retrospective cohort study.

May 13, 2021

Stress fractures (SF) are injuries that can result from beginning new or higher volume physical training regimens. The pattern of clinical presentation of SF over time after individuals start a new or...

An SNX10-dependent mechanism downregulates fusion between mature osteoclasts.

May 13, 2021

Homozygosity for the R51Q mutation in sorting nexin 10 (SNX10) inactivates osteoclasts (OCLs) and induces autosomal recessive osteopetrosis in humans and in mice. We show here that the fusion of wild-...

Risk Factors and Clinical Characteristics of Metabolic Bone Disease of Prematurity.

May 13, 2021

 The study aimed to analyze the risk factors and clinical features of metabolic bone disease of prematurity (MBDP) in premature infants compared with infants of similar gestational age and birthweig...

Acute Response of Sclerostin to Whole-body Vibration with Blood Flow Restriction.

May 13, 2021

Blood flow restriction may augment the skeletal response to whole-body vibration. This study used a randomised, crossover design to investigate the acute response of serum sclerostin and bone turnover...

Dietary patterns and hip fracture in the Adventist Health Study 2: combined vitamin D and calcium supplementation mitigate increased hip fracture risk among vegans.

May 10, 2021

Concerns regarding the adequacy of vegetarian diets with respect to fracture risk continue.We aimed to explore the influence of 5 previously defined dietary patterns on hip fracture risk and whether t...

Pancreaticoduodenectomy for hepatic portal lymph node metastasis after hepatic resection for hepatocellular carcinoma: A clinical case report.

May 10, 2021

In 2018, Hepatocellular carcinoma (HCC) was predicted to be the sixth most commonly diagnosed cancer. Extra-hepatic metastasis due to HCC is a poor prognostic factor, depending on the stage of the dis...

Estrogen receptor α in mature osteoblasts regulates the late stage of bone regeneration.

May 10, 2021

Estrogen deficiency impairs fracture healing and homeostasis of bone tissue. OVX-induced estrogen deficiency in mice attenuates fracture healing and changes the expression ratio of estrogen receptor (...

Use of a Double Reverse Traction Repositor versus a Traction Table for the Treatment of Intertrochanteric Femur Fractures: A Comparative Study.

May 06, 2021

The aim of the present study was to compare the clinical results for unstable femoral intertrochanteric fractures treated with a double reverse traction repositor (DRTR) and those treated using a trac...

Anatomical Location of Initial and Repeat Mandible Fractures: A 5-Year, Multi-Institution Retrospective Study.

May 06, 2021

The purpose of the present study was to investigate new fracture patterns resulting from low velocity mechanisms in subjects who had previously fractured their mandible and had been treated with open ...

The association of Spondylitis and Aortic Aneurysm Disease.

May 06, 2021

The aim of this study is to assess any relation between spondylitis and aortic aneurysmal disease by reviewing the current literature.A systematic search was undertaken using MEDLINE, EMBASE and CENTR...

Comprehensive Interventions Including Vitamin D Effectively Reduce the Risk of Falls in Elderly Osteoporotic Patients.

May 06, 2021

To evaluate the effects of different intervention measures to prevent falls in elderly osteoporotic patients.A randomized controlled trial was conducted in our outpatient ward from August 2014 to Sept...

Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients.

May 06, 2021

The pioneer transcription factor (TF) PU.1 controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing nonpioneer TFs to enter otherwise inaccessible genomic sites. PU.1 de...

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