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Orthopedics General

How we approach the treatment of patients with high-risk neuroblastoma with naxitamab: experience from the Hospital Sant Joan de Déu in Barcelona, Spain.

Apr 11, 2022

Naxitamab [humanized 3f8 (hu3F8)] is a humanized monoclonal antibody (mAb) targeting the disialoganglioside GD2. It was approved in 2020 by the United States Food and Drug Administration (FDA) in com...

Methodological Considerations for Investigating Iron Status and Regulation in Exercise and Sport Science Studies.

Apr 04, 2022

Iron deficiency is a common health issue in active and athlete populations. Accordingly, research into iron status, regulation, absorption, and iron deficiency treatment strategies is increasing at a ...

Numerical modelling of cancellous bone damage using an orthotropic failure criterion and tissue elastic properties as a function of the mineral content and microporosity.

Apr 04, 2022

Elastic and strength properties of lamellar tissue are essential to analyze the mechanical behaviour of bone at the meso- or macro-scale. Although many efforts have been made to model the architecture...

Vertical root fractures in root treated teeth-current status and future trends.

Mar 28, 2022

Vertical root fracture (VRF) is a common reason for the extraction of root filled teeth. The accurate diagnosis of VRF may be challenging due to the absence of clinical signs, whilst conventional radi...

Blue light potentiates safety and bactericidal activity of p-Toluquinone.

Mar 28, 2022

Fewer antibiotics are available for effective management of bacterial infections to date owing to increasing multiple-drug resistance (MDR). Here, we expand our early success in combination of 405 nm...

Recombinant guanosine-5'-triphosphate (GTP)-binding protein associated with Poloxamer 407-based polymeric micelles protects against Leishmania infantum infection.

Mar 28, 2022

Leishmania virulence proteins should be considered as vaccine candidates against disease, since they are involved in developing infection in mammalian hosts. In a previous study, a Leishmania guanosin...

Adjustable-loop cortical suspension device for posterolateral corner reconstruction in the setting of fibular avulsion fracture: a case series and novel technique description.

Mar 21, 2022

A novel technique using an adjustable-loop cortical suspension toggle device for reduction of a fibular head avulsion fracture (arcuate fracture) in posterolateral corner (PLC) reconstruction is descr...

Arthroscopic fixation for tibial eminence fractures: A clinical retrospective study of cannulated screws versus transosseous anchor knot fixation techniques with suture anchors.

Mar 21, 2022

A variety of different techniques or methods for treatment of tibial eminence fracture (TEF) have been reported, but there is still controversy on the optimum choice for treating TEFs. The aim of the ...

Osgood-Schlatter Disease in youth elite football: Minimal time-loss and no association with clinical and ultrasonographic factors.

Mar 21, 2022

Osgood-Schlatter Disease is the most common cause of knee pain in youth. Scientific research in youth elite football is limited.To assess clinical and ultrasonographic factors associated with Osgood-S...

Computed Tomographic Features of Non-Lame French Bulldog Elbows.

Mar 14, 2022

 French Bulldogs are predisposed to humeral condylar fractures. Computed tomography (CT) in English Springer Spaniel elbows has allowed identification of humeral intracondylar fissures (HIF), which ...

Pumping the Periosteum: A Feasibility Study: Periosteal Distraction Osteogenesis in a Rat Model.

Mar 14, 2022

Gradual elevation of periosteum from the bone surface is known to promote the adaptation of soft tissues and the formation of hard tissues. The aim of our study was to estimate the benefit of perioste...

With Lacking Data, Estimating The Oswestry Disability Index Measurement Error

Mar 11, 2022

The Oswestry Disability Index (ODI) was the most often used patient-reported outcome measure for low back pain. Incomplete ODI questionnaires can lead to measurement errors, leading to misclassificati...

After Single-Level Posterior Lumbar Interbody Fusion, Risk Factors For Early-Onset Radiographical Adjacent Segment Disease in Patients With Spondylolysis Spondylolisthesis

Mar 11, 2022

For a study, the researchers sought to determine any risk variables for radiographic ASD in individuals who had single-level PLIF for L5–S1 spondylolysis spondylolisthesis. The researchers conducted...

Computed Tomography Evaluation of Bone Mineral Density After Instrumented Lumbar Fusion

Mar 11, 2022

The measurement of Hounsfield Units (HU) by computed tomography (CT) has been reported as a technique for determining Bone Mineral density (BMD). The BMD of the UIV was useful for surgical planning fo...

Validity of the Training-Load Concept.

Mar 07, 2022

Training load (TL) is a widely used concept in training prescription and monitoring and is also recognized as as an important tool for avoiding athlete injury, illness, and overtraining. With the wide...

Conservative management of Jones fractures with immediate weight-bearing in a walking boot demonstrates healing.

Feb 28, 2022

Jones fractures, or proximal metatarsal fractures at the level of the fourth and fifth intermetatarsal junction, have a high risk for nonunion due to a vascular watershed region. Classically, treatmen...

The coexistence of os trigonum, accessory navicular bone and os peroneum and associated tendon and bone pathologies.

Feb 28, 2022

To determine how often os trigonum is accompanied by accessory navicular and os peroneum. A secondary aim of the study was to investigate the bone and related tendon pathologies that may develop in th...

Changes in subchondral bone structure and mechanical properties do not substantially affect cartilage mechanical responses - A finite element study.

Feb 28, 2022

Subchondral bone structure has been observed to change in osteoarthritis (OA). However, it remains unclear how the early-stage OA changes affect the mechanics (stresses and strains) of the osteochondr...

Hyperbaric oxygen therapy improves age induced bone dyshomeostasis in non-obese and obese conditions.

Feb 21, 2022

To investigate the effects of hyperbaric oxygen therapy (HBOT) on metabolic disturbance, aging and bone remodeling in D-galactose-induced aging rats with and without obesity by determining the metabol...

Comparing metabolic profiles between endurance athlete and non-athlete females reveals differences in androgenic and corticosteroids levels.

Feb 21, 2022

Endurance training is associated with physiological changes in elite athletes, but little is known about female-specific effects of endurance training. Despite the significant rise in female sports pa...

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