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Orthopedics General

Prevalence and risk factors of fractures in transfusion dependent thalassemia - A Hong Kong Chinese population cohort.

May 02, 2022

To delineate the prevalence and associated risk factors of low BMD, osteoporosis/bone fragility and fracture in transfusion-dependent thalassemia (TDT) in the Chinese population in Hong Kong.A retrosp...

A new surgical strategy for the treatment of tibial pilon fractures with MIPO facilitated by double reverse traction repositor.

May 02, 2022

The present study aims to introduce a technique combining double reverse traction repositor (DRTR) with minimally invasive plate osteosynthesis (MIPO) in the surgical treatment of pilon fractures and ...

Loss of parathyroid hormone receptor signaling in osteoprogenitors is associated with accumulation of multiple hematopoietic lineages in the bone marrow.

May 02, 2022

Osteoblasts and their progenitors play an important role in the support of hematopoiesis within the bone marrow microenvironment. We have previously reported that parathyroid hormone receptor (PTH1R) ...

Splenic Gaucheroma Leading to Incidental Diagnosis of Gaucher Disease in a 46-Year-Old Man with a Rare GBA Mutation: A Case Report.

May 02, 2022

Gaucher disease is a common lysosomal storage disease caused by the deficiency of β-glucosidase enzyme, leading to sphingolipid accumulation in the reticuloendothelial system in Gaucher cells. Clinic...

Rates of complications in Achilles tendon rupture repair using absorbable and nonabsorbable suture material; A systematic review.

Apr 25, 2022

The impact of suture type on tensile strength, re-rupture rates and infection risk in Achilles tendon rupture repair is not been well established. The aim of this review is to evaluate existing litera...

Prevalence of Rotator Cuff Tears Among Older Tennis Players and Its Impact on Clinical Findings and Shoulder Function.

Apr 25, 2022

Tennis is a noncontact sport playable at an individual's own pace. Thus, it is popular among the older adults. It is known that older adults often suffer from rotator cuff tears (RCTs), which may affe...

Repair of distal fibular and lateral malleolus defects with individualized 3D-printed titanium alloy prosthesis: The first case report from China.

Apr 25, 2022

This case report describes the reconstruction of the traumatic distal fibular and lateral malleolus defects with a novel method of using individualized 3D printed titanium prosthesis for the first tim...

Severe headache and seizure free after microscopic fenestration craniotomy of middle Fossa arachnoid cyst: Case series.

Apr 25, 2022

Arachnoid cyst in the middle fossa can cause many symptoms include headache and seizure. When drugs therapy can not relieve or control the symptoms, it is necessary to determine whether the surgical p...

Odontoid fracture complicating ankylosing spondylitis presenting with cervical canal stenosis and quadriparesis: A case report with 5-year follow-up and review of the literature.

Apr 18, 2022

Spinal fractures, especially cervical fractures, are more common in patients with ankylosing spondylitis in comparison with unaffected patients. However, odontoid fractures are relatively rare in thes...

Osteosarcoma: Novel prognostic biomarkers using circulating and cell-free tumour DNA.

Apr 18, 2022

Osteosarcoma (OS) is the most common primary bone tumour in children and adolescents. Circulating free (cfDNA) and circulating tumour DNA (ctDNA) are promising biomarkers for disease surveillance and ...

Assessment of complications associated with casting of acute distal radius fractures in adults.

Apr 11, 2022

Controversy exists regarding the closed treatment of distal radius fractures. Circumferential casting of acute distal radius fractures has been shown to be safe in children, however, little research h...

Higher stress and symptom severity are associated with worse depressive symptom profiles in patients receiving chemotherapy.

Apr 11, 2022

In a sample of oncology patients, identify subgroups of patients with distinct depressive symptom profiles and evaluate for differences in demographic and clinical characteristics, levels of stress an...

Lived experience of State-sponsored intra-national overseas therapeutic mobility for stem cell transplantation.

Apr 11, 2022

This article focuses on the lived experience of patients with haematological cancer who were transferred from La Réunion (a French overseas Department) to mainland France to undergo allogeneic haemat...

How we approach the treatment of patients with high-risk neuroblastoma with naxitamab: experience from the Hospital Sant Joan de Déu in Barcelona, Spain.

Apr 11, 2022

Naxitamab [humanized 3f8 (hu3F8)] is a humanized monoclonal antibody (mAb) targeting the disialoganglioside GD2. It was approved in 2020 by the United States Food and Drug Administration (FDA) in com...

Methodological Considerations for Investigating Iron Status and Regulation in Exercise and Sport Science Studies.

Apr 04, 2022

Iron deficiency is a common health issue in active and athlete populations. Accordingly, research into iron status, regulation, absorption, and iron deficiency treatment strategies is increasing at a ...

Numerical modelling of cancellous bone damage using an orthotropic failure criterion and tissue elastic properties as a function of the mineral content and microporosity.

Apr 04, 2022

Elastic and strength properties of lamellar tissue are essential to analyze the mechanical behaviour of bone at the meso- or macro-scale. Although many efforts have been made to model the architecture...

Vertical root fractures in root treated teeth-current status and future trends.

Mar 28, 2022

Vertical root fracture (VRF) is a common reason for the extraction of root filled teeth. The accurate diagnosis of VRF may be challenging due to the absence of clinical signs, whilst conventional radi...

Blue light potentiates safety and bactericidal activity of p-Toluquinone.

Mar 28, 2022

Fewer antibiotics are available for effective management of bacterial infections to date owing to increasing multiple-drug resistance (MDR). Here, we expand our early success in combination of 405 nm...

Recombinant guanosine-5'-triphosphate (GTP)-binding protein associated with Poloxamer 407-based polymeric micelles protects against Leishmania infantum infection.

Mar 28, 2022

Leishmania virulence proteins should be considered as vaccine candidates against disease, since they are involved in developing infection in mammalian hosts. In a previous study, a Leishmania guanosin...

Adjustable-loop cortical suspension device for posterolateral corner reconstruction in the setting of fibular avulsion fracture: a case series and novel technique description.

Mar 21, 2022

A novel technique using an adjustable-loop cortical suspension toggle device for reduction of a fibular head avulsion fracture (arcuate fracture) in posterolateral corner (PLC) reconstruction is descr...

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