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Ophthalmology General

Preventing Neurodegeneration by Controlling Oxidative Stress: The Role of OXR1.

Jan 04, 2021

Parkinson's disease, diabetic retinopathy, hyperoxia induced retinopathy, and neuronal damage resulting from ischemia are among the notable neurodegenerative diseases in which oxidative stress occurs ...

The phase changes of M1/M2 phenotype of microglia/macrophage following oxygen-induced retinopathy in mice.

Jan 04, 2021

Microglia/macrophage activation is previously reported to be involved in various ocular diseases. However, the separate role of M1/M2 phenotype microglia/macrophage in the pathological process of oxyg...

Safety and efficacy of bilateral simultaneous XEN implant surgery: a pilot study.

Jan 04, 2021

To evaluate the efficacy and safety of the bilateral simultaneous XEN (BISIXEN) surgery in open-angle glaucoma patients.Retrospective analysis of a prospective data base conducted on uncontrolled glau...

Effects of glaucoma and central corneal thickness on optic nerve head biomechanics.

Jan 04, 2021

To evaluate effects of glaucoma and central corneal thickness (CCT) on optic nerve head biomechanics.Four groups were formed according to CCT measurements and the presence of glaucoma. Glaucomatous pa...

Can unconscious intentions be more effective than conscious intentions? Test of the role of metacognition in hypnotic response.

Jan 04, 2021

While several theories assume that responses to hypnotic suggestions can be implemented without executive intentions, the metacognitive class of theories postulate that the behaviors produced by hypno...

Long term Surgical Outcomes of Primary Congenital Glaucoma in a South Indian population.

Dec 31, 2020

To evaluate the long term surgical outcomes of children with primary congenital glaucoma (PCG) in a South Indian population.This retrospective cohort study included children with PCG who have had surg...

The association between immune checkpoint or BRAF/MEK inhibitor therapy and uveitis in patients with advanced cutaneous melanoma.

Dec 31, 2020

Treatment with immune checkpoint and BRAF/MEK inhibitors has significantly improved the survival of patients with advanced cutaneous melanoma and other metastatic malignancies. Therapy-related uveitis...

Spectrum of Disease Severity in Patients With X-Linked Retinitis Pigmentosa Due to RPGR Mutations.

Dec 31, 2020

The purpose of this study was to perform a detailed longitudinal phenotyping of X-linked retinitis pigmentosa (RP) caused by mutations in the RPGR gene during a long follow-up period.An Italian cohort...

Categorisation of myopia progression by change in refractive error and axial elongation and their impact on benefit of myopia control using orthokeratology.

Dec 31, 2020

To compare the value of pre-treatment axial elongation (AE) and changes in refractive sphere (M change) for predicting the success in orthokeratology (ortho-k), in order to better identify suitable ca...

Proteomic analysis of aqueous humor in patients with pathologic myopia.

Dec 31, 2020

Complications from pathologic myopia (PM) are a major cause of visual impairment and blindness. However, an efficient clinical therapeutic strategy for PM is still lacking. The aim of this study was t...

Safety and Tolerability of an Eye Drop Based on 0.6% Povidone-Iodine Nanoemulsion in Dry Eye Patients.

Dec 31, 2020

To evaluate safety and tolerability on the ocular surface of an anti-septic formulation containing 0.6% povidone-iodine (0.6% PVI) for a 4 week period. An observational, prospective study included 2...

Safety and Efficacy of an Augmented Intense Pulse Light Protocol for Dry Eye Syndrome and Blepharitis.

Dec 31, 2020

We evaluated the safety and efficacy of an augmented BroadBand Light (BBL™) protocol on the upper and lower eyelids in improving meibomian gland dysfunction (MGD) and/or dry eye disease (DED)....

[Eyelid hygiene in preparing dry eye patients for cataract surgical treatment].

Dec 31, 2020

To evaluate the effectiveness of complex treatment, including eyelid hygiene, on the condition of ocular surface in dry eye patients before cataract surgery.The study included 56 female age-related ca...

Immunological biomarkers of the vitreous responsible for proliferative alteration in the different forms of retinal detachment.

Dec 31, 2020

The purpose of the study was to explore the immunological components that are responsible for the proliferative alterations in the different forms of retinal detachment (RD).Vitreous fluids were colle...

Association of Non-alcoholic Fatty Liver Disease with Diabetic Retinopathy in Type 2 Diabetic Patients: A Meta-Analysis of Observational Studies.

Dec 31, 2020

Non-alcoholic fatty liver disease (NAFLD) is becoming more and more prevalent in type 2 diabetes mellitus(T2DM). Evidences connecting NAFLD to diabetic retinopathy (DR) are increasing, but the resul...

Hydrogen Sulfide: A Potential Therapeutic Target in the Development of Diabetic Retinopathy.

Dec 31, 2020

Hyperglycemia damages the retinal mitochondria, and the mitochondrial damage plays a central role in the development of diabetic retinopathy. Patients with diabetes also have higher homocysteine level...

[Development of additive systemic effects when taking β-blockers in patients with glaucoma and concurrent chronic diseases].

Dec 31, 2020

Examining the somatic state of glaucomatous patients that enroll for treatment, we are increasingly confronted with a serious problem of inconsistency in prescribing beta-blockers (β-blockers) by oph...

[Anti-angiogenesis therapy of diabetic macular edema in patients with primary open-angle glaucoma].

Dec 31, 2020

Despite the high clinical effectiveness and widespread introduction of anti-angiogenesis (anti-VEGF) therapy into practice, its long-term effect on the development of structural changes in the treatme...

[Surgical treatment of congenital glaucoma in children using Glautex drainage].

Dec 31, 2020

Purpose - to study the effectiveness of surgical treatment of congenital glaucoma in children comparatively with the use of Glautex, and fistulizing surgery using autoscleral drainage.Clinical studies...

Office- or Facility-Based Probing for Congenital Nasolacrimal Duct Obstruction: A Report by the American Academy of Ophthalmology.

Dec 31, 2020

To review the published literature assessing the efficacy and safety of in-office probing compared with facility-based probing to treat congenital nasolacrimal duct obstruction (NLDO).Literature searc...

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