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Ophthalmology General

[Nystagmus secondary to albinism with ocular involvement in a female: A diagnostic challenge].

Jan 07, 2021

Infantile nystagmus is an infrequent condition that represents a diagnostic challenge for the pediatri cian. Albinism is one of its main causes, being difficult to suspect in the absence of evident cu...

The distribution of conjunctival goblet cells in mice.

Jan 07, 2021

To evaluate the density and distribution of conjunctival goblet cells in mice without clinical evidence of ocular surface diseases.Immediately after euthanasia of C57BL/6 wild-type mice, the eyes incl...

Manuscript title: Developing evidence-based guidance for the treatment of dry eye disease with artificial tear supplements: A six-month multicentre, double-masked randomised controlled trial.

Jan 07, 2021

To assess the six-month therapeutic profiles of lipid and non-lipid-based artificial tear supplements in managing dry eye disease (DED).Ninety-nine participants fulfilling the TFOS DEWS II diagnostic ...

Automatic Detection of Genetics and Genomics of Eye Disease Using Deep Assimilation Learning Algorithm.

Jan 07, 2021

Diabetic retinopathy (DR) is one of the most prevalent genetic diseases in human and it is caused by damage to the blood vessels in the eye retina. If it is undetected and untreated at right time, it ...

The colorful world of carotenoids: a profound insight on therapeutics and recent trends in nano delivery systems.

Jan 07, 2021

The therapeutic effects of carotenoids as dietary supplements to control or even treat some specific diseases including diabetic retinopathy, cardiovascular diseases, bacterial infections, as well as ...

Retinopathy in adults with hypertension and diabetes mellitus in Western Tanzania: a cross-sectional study.

Jan 07, 2021

Little is known about the retinal manifestations of arterial hypertension (HTN) and diabetes mellitus (DM) in Western Tanzania and how to maximise the utilisation of scarce eye health resources. To ad...

Olfactory language and semantic processing in anosmia: a neuropsychological case control study.

Jan 07, 2021

A longstanding debate within philosophy and neuroscience involves the extent to which sensory information is a necessary condition for conceptual knowledge. Much of our understanding of this relations...

NRL gene edited human embryonic stem cells generate rod-deficient retinal organoids enriched in S-cone-like photoreceptors.

Jan 07, 2021

Organoid cultures represent a unique tool to investigate the developmental complexity of tissues like the human retina. NRL is a transcription factor required for the specification and homeostasis of ...

[Vascular malformations of the head and neck].

Jan 07, 2021

Vascular malformations are congenital anomalies of the vascular system that often affect the head and neck region. Vascular malformations are typically present at birth and proportionately grow with t...

Reducing the Global Burden of Myopia by Delaying the Onset of Myopia and Reducing Myopic Progression in Children: The Academy's Task Force on Myopia.

Jan 07, 2021

In 2019, the American Academy of Ophthalmology (AAO) created the Task Force on Myopia in recognition of the substantial global increases in myopia prevalence and its associated complications. The Task...

Aggregated neutrophil extracellular traps occlude Meibomian glands during ocular surface inflammation.

Jan 07, 2021

Obstructive Meibomian gland dysfunction (MGD) is one of the leading causes of evaporative dry eye disease. Meibomian glands at the eyelid secrete lipids that prevent evaporation of the aqueous tear fi...

Orbital metastasis of squamous cell cervical cancer: A case report and review of literature.

Jan 04, 2021

Common sites of metastatic disease seen in cervical cancer most often include the lungs and liver. Orbital metastasis secondary to cervical carcinoma is a rare form of metastatic disease. We report a ...

Association of HTRA1 and CFH gene polymorphisms with age-related macular degeneration in Ningbo, China.

Jan 04, 2021

Age-related macular degeneration (AMD) is one of the major causes of blindness, and the incidence of this disease has been increasing in recent years.To investigate the association between the single ...

Pharmacotherapeutic candidates for myopia: A review.

Jan 04, 2021

This review provides insights into the mechanism underlying the pathogenesis of myopia and potential targets for clinical intervention. Although the etiology of myopia involves both environmental and ...

Natural history of glaucomatous optic neuropathy in highly myopic Chinese: study protocol for a registry cohort study.

Jan 04, 2021

Myopic maculopathy and glaucoma belong to the most common causes of irreversible blindness worldwide and, having an ocular axial elongation as one of their main risk factors, can occur together. The d...

Pediatric Keratoconus: Topographic, Biomechanical and Aberrometric Characteristics.

Jan 04, 2021

Evaluation of the demographic profile, clinical features, topographic, biomechanical and aberrometric characteristics in pediatric keratoconus (KC).Cross-sectional study METHODS: Cases with KC aged &l...

Dermatologists' Knowledge and Attitudes Toward Dry Eye Disease, Refractive Surgery, and Contact Lenses When Prescribing Isotretinoin in Saudi Arabia.

Jan 04, 2021

This study assesses the knowledge and attitudes of dermatologists in Saudi Arabia with regard to dry eye disease, refractive surgery, and contact lenses when prescribing isotretinoin.A total of 150 de...

Serological and hematological characteristics of Sjogren's syndrome and dry eye syndrome patients using a novel immune serology technique.

Jan 04, 2021

To compare hematologic and serological parameters among patients with Sjogren's syndrome (SS), dry eye syndrome (DES) and controls, and validate a novel multiplex-serology method for identifying auto-...

Ocular Involvement in Sjogren's Syndrome: Risk Factors for Severe Visual Impairment and Vision-Threatening Corneal Complications.

Jan 04, 2021

To assess the risk factors for severe visual impairment (SVI) and corneal complications in primary and secondary Sjogren's syndrome (SS).Retrospective case series.Ocular data of all consecutive SS pat...

RNA-Seq analysis reveals gene expression changes induced by IL-6 trans-signaling activation in retinal endothelial cells.

Jan 04, 2021

Increasing evidence suggests that interleukin-6 (IL-6) trans-signaling plays a critical role in the pathogenesis of diabetic retinopathy (DR). We have previously shown that activation of IL-6 trans-si...