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Ophthalmology General

Incidence and progression of diabetic retinopathy in a multi-ethnic US cohort: the Multi-Ethnic Study of Atherosclerosis.

Mar 22, 2021

To provide contemporary longitudinal data on the incidence and progression of diabetic retinopathy (DR) in a multi-ethnic population of whites, African Americans, Chinese and Hispanics in the United S...

Shortening the Early Treatment Diabetic Retinopathy Study visual acuity test utilizing a novel computer software: reproducibility in control and patient eyes.

Mar 22, 2021

To describe and compare a method of computerized visual acuity (VA) testing software to the Early Treatment Diabetic Retinopathy Study (ETDRS) chart.Setting: Single tertiary institution.Prospective st...

Parapapillary deep-layer microvasculature dropout is only found near the retinal nerve fibre layer defect location in open-angle glaucoma.

Mar 22, 2021

We aimed to investigate the topographic correspondence between deep-layer microvasculature dropout (MvD) and retinal nerve fibre layer (RNFL) defects in eyes with open-angle glaucoma (OAG) using spect...

Circumferential (360°) trabeculotomy in primary congenital glaucoma: 19-245 months of follow-up.

Mar 22, 2021

To evaluate the long-term efficacy and safety of circumferential trabeculotomy (CT) in the treatment of primary congenital glaucoma (PCG).Retrospective, single-institutional case series of CT performe...

Outcomes of Subliminal Transscleral Cyclophotocoagulation treatment in glaucoma.

Mar 22, 2021

Subliminal transscleral cyclophotocoagulation (SL-TSCPC) is a new alternative therapy to reduce intraocular pressure (IOP) safely and effectively. However, there are few studies regarding SL-TSCPC by ...

Ophthalmic Technology Assessment: Multifocal and Accommodating Intraocular Lenses for the Treatment of Presbyopia A report by the American Academy of Ophthalmology.

Mar 22, 2021

To review the published literature assessing the efficacy and safety of presbyopia-correcting intraocular lenses (IOLs) for the treatment of presbyopia after cataract removal.Literature searches were ...

Updates on Genes and Genetic Mechanisms Implicated in Primary Angle-Closure Glaucoma.

Mar 18, 2021

Primary angle-closure glaucoma (PACG) is estimated to affect over 30 million people worldwide by 2040 and is highly prevalent in the Asian population. PACG is more severe and carries three times the h...

Structural aspects of rod opsin and their implication in genetic diseases.

Mar 18, 2021

Vision in dim-light conditions is triggered by photoactivation of rhodopsin, the visual pigment of rod photoreceptor cells. Rhodopsin is made of a protein, the G protein coupled receptor (GPCR) opsin,...

Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness.

Mar 18, 2021

Complete congenital stationary night blindness (cCSNB) is an incurable inherited retinal disorder characterized by an ON-bipolar cell (ON-BC) defect. GRM6 mutations are the third most prevalent cause ...

Relationship between Axial Length and Levels of TGF- in the Aqueous Humor and Plasma of Myopic Patients.

Mar 18, 2021

To investigate the levels of transforming growth factor- (TGF-) in human aqueous humor (AH) and plasma (PL) of patients with myopia, and verify whether there is an association between these levels and...

Bardet-Biedl syndrome-7 () shows treatment potential and a cone-rod dystrophy phenotype that recapitulates the non-human primate model.

Mar 18, 2021

: To provide a detailed ophthalmic phenotype of two male patients with Bardet-Biedl Syndrome (BBS) due to mutations in the gene: Two brothers ages 26 (Patient 1, P1) and 23 (P2) underwent comprehensi...

The Clouclip, a wearable device for measuring near-work and outdoor time: validation and comparison of objective measures with questionnaire estimates.

Mar 18, 2021

To validate a novel wearable device that can measure both viewing distance and light exposure, Clouclip, and compare questionnaire estimates regarding near-work and outdoor time with the objective mea...

Repeatability of Non-invasive Keratograph Break-Up Time measurements obtained using Oculus Keratograph 5M.

Mar 18, 2021

The aim of this study is to assess the intraexaminer repeatability of Non-invasive Keratograph Break-Up Time (NIKBUT) obtained using the Oculus Keratograph 5M (K5M), given its relevance as a homeostas...

Overview of Ocular Side Effect of Selinexor.

Mar 18, 2021

The aim of this review is to elucidate the type and frequency of ocular adverse events associated with selinexor with a goal to quantify the occurrence of these events in our investigator-initiated tr...

Exploring the human lacrimal gland using organoids and single-cell sequencing.

Mar 18, 2021

The lacrimal gland is essential for lubrication and protection of the eye. Disruption of lacrimal fluid production, composition, or release results in dry eye, causing discomfort and damage to the ocu...

Evaluating the Viability of a Smartphone-Based Annotation Tool for Faster and Accurate Image Labelling for Artificial Intelligence in Diabetic Retinopathy.

Mar 18, 2021

Deep Learning (DL) and Artificial Intelligence (AI) have become widespread due to the advanced technologies and availability of digital data. Supervised learning algorithms have shown human-level perf...

Injury Related to Fall and Its Predictors among Medically Diagnosed Adults with Visual Impairment in Ethiopia: An Observational Cross-Sectional Study.

Mar 18, 2021

Fall-related injury is the common cause of unintentional injury and premature death among people with visual impairment. So far, the knowledge about fall-related injuries among medically diagnosed vis...

Diabetic Macular Edema Treatment with Bevacizumab Does Not Depend on the Retinal Nonperfusion Presence.

Mar 18, 2021

This study evaluated the relationship between the retinal nonperfusion area (NPA) presence and the effectiveness of bevacizumab treatment (IVB) in patients with diabetic macular edema (DME). It also t...

[Treatment of vascularized high-risk eyes with a Boston keratoprosthesis].

Mar 18, 2021

In severely compromised and vascularized high-risk eyes, the Boston keratoprosthesis procedure is often the last treatment option. The transparency of the optics is not impaired by endothelial immune ...

Aetiology and clinical characteristics of uveitic glaucoma in Turkish patients.

Mar 18, 2021

To investigate the types, frequency and clinical profiles of uveitic glaucoma seen at a tertiary care center and also to have an idea about the distribution of uveitic glaucoma types in Turkish popula...