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Ophthalmology General

Identification of MFRP and the secreted serine proteases PRSS56 and ADAMTS19 as part of a molecular network involved in ocular growth regulation.

Mar 25, 2021

Precise regulation of ocular size is a critical determinant of normal visual acuity. Although it is generally accepted that ocular growth relies on a cascade of signaling events transmitted from the r...

Transepithelial photorefractive keratectomy to treat mild myopia.

Mar 25, 2021

To assess the safety and effectiveness of transepithelial photorefractive keratectomy (T-PRK) in patients with mild myopia using the Schwind Amaris 750 s Excimer laser system which take corneal epith...

Ocular manifestations and biomarkers of Gulf War Illness in US veterans.

Mar 25, 2021

Gulf War Illness (GWI) is a multisystem disease with variable presentations, making diagnosis difficult. Non-invasive biomarkers would aid in disease diagnosis. We hypothesized that the eye could serv...

Prevalence of dry eye syndrome in association with the use of contact lenses in Saudi Arabia.

Mar 25, 2021

Dry eye disease is a tear film disorder which can cause discomfort to patients and negatively affect vision acuity. A number of risk factors has been reported to affect the incidence and severity of d...

Critical role of mass spectrometry proteomics in tear biomarker discovery for multifactorial ocular diseases (Review).

Mar 25, 2021

The tear film is a layer of body fluid that maintains the homeostasis of the ocular surface. The superior accessibility of tears and the presence of a high concentration of functional proteins make te...

Surgery for idiopathic epiretinal membrane.

Mar 25, 2021

Epiretinal membrane is an abnormal sheet of avascular fibrocellular tissue that develops on the inner surface of the retina. Epiretinal membrane can cause impairment of sight as a consequence of progr...

Protective role of vitamin D against oxidative stress in diabetic retinopathy.

Mar 25, 2021

Diabetic retinopathy (DR) is a microvascular complication of diabetes mellitus. There is much evidence showing that a high level of mitochondrial overproduction of reactive oxygen species in the diabe...

Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway.

Mar 25, 2021

Proliferative vitreoretinopathy (PVR) is a disease leading to the formation of contractile preretinal membranes (PRMs) and is one of the leading causes of blindness. Connective tissue growth factor (...

Smartphone usage among people living with severe visual impairment and blindness.

Mar 25, 2021

Low vision care and rehabilitation is often limited by access to assistive devices especially in low resourced countries due to their high cost and unavailability. Smartphones have the potential to se...

The Potential Application of Pentacyclic Triterpenoids in the Prevention and Treatment of Retinal Diseases.

Mar 25, 2021

Retinal diseases are a leading cause of impaired vision and blindness but some lack effective treatments. New therapies are required urgently to better manage retinal diseases. Natural pentacyclic tri...

Plasma fatty acids and primary open-angle glaucoma in the elderly: the Montrachet population-based study.

Mar 25, 2021

To compare plasma fatty acids (FAs) between participants with primary open-angle glaucoma (POAG) and participants without neuropathy in an elderly population and to investigate specific FAs pattern in...

Early radiotherapy preserves vision in sporadic optic pathway glioma.

Mar 22, 2021

Sporadic optic pathway/hypothalamic gliomas represent a unique entity within pediatric low-grade glioma. Despite favorable survival, location makes treatment difficult and local progression debilitati...

A small molecular multi-targeting tyrosine kinase inhibitor, anlotinib, inhibits pathological ocular neovascularization.

Mar 22, 2021

Ocular neovascularization is a devastating pathology observed in numerous ocular diseases and is a major cause of blindness. However, all current treatments have their limitations. Hence, it is import...

Treatments for dry age-related macular degeneration: therapeutic avenues, clinical trials and future directions.

Mar 22, 2021

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the developed world. The identification of the central role of vascular endothelial growth factor (VEGF) in the...

[Comparative analysis of refractive and topographic changes after eyelid surgery].

Mar 22, 2021

There is largely a lack of clarity on the question of whether refraction or topography changes are to be expected after blepharoplasty, levator resection, or a lateral tarsal strip procedure.Therefo...

The impact of hemodialysis on retinal and choroidal thickness in patients with chronic renal failure.

Mar 22, 2021

Patients with chronic renal failure are commonly cared using a blood filtration mechanism like hemodialysis. Little information is available regarding ocular changes following hemodialysis for people ...

OUR EXPERIENCE WITH ACTIVE SENTRY AND CENTURION OZIL HANDPIECES.

Mar 22, 2021

To compare parameters of phacoemulsification using handpiece Active Sentry and Centurion Ozil.We have evaluated results of 200 eyes of 129 patients that were operated for cataract at the Department of...

Ophthalmic assessment in patients with Darier disease: Ophthalmic assessment in Darier disease.

Mar 22, 2021

To assess the prevalence of ophthalmic findings in patients with Darier disease, an autosomal dominant genetic skin disorder, in an effort to evaluate the need for eye examinations in the management o...

Evaluation of dry eye disease in children with blepharokeratoconjunctivitis.

Mar 22, 2021

To evaluate the symptoms and signs of dry eye disease (DED) in children diagnosed with blepharokeratoconjunctivitis (BKC).Prospective case-controlled study PARTICIPANTS: Consecutive patients with BKC ...

Randomized, crossover clinical efficacy trial in humans and mice on tear secretion promotion and lacrimal gland protection by molecular hydrogen.

Mar 22, 2021

The incidence of dry eye disease is increasing worldwide because of the aging population and increasing use of information technology. Dry eye disease manifests as tear-layer instability and inflammat...

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