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Ophthalmology General

The Enduring Experience in Dry Eye Diagnosis: A Non-Interventional Study Comparing the Experiences of Patients Living With and Without Sjögren's Syndrome.

Apr 05, 2021

Previous studies have examined the patient experience regarding the diagnosis and management of dry eye disease (DED). The current study explored the ways in which the DED diagnostic pathway differs f...

Ocular Manifestations in Patients of HIV(Human Immunodeficiency Virus) Infection on Combined Anti-Retroviral Therapy (CART).

Apr 05, 2021

: To determine the prevalence and spectrum of ocular manifestations in PLHIV (people living with Human Immunodeficiency Virus) on cART (combined Antiretroviral Therapy) and correlate them with WHO cli...

The Relationship Between Circulating Growth Differentiation Factor 15 Levels and Diabetic Retinopathy in Patients With Type 2 Diabetes.

Apr 05, 2021

Growth differentiation factor 15 (GDF-15) is a member of the TGF- superfamily that has anti-inflammatory properties. The objective of this study was to evaluate the relationship between circulating GD...

Atg16L1 as a Novel Biomarker and Autophagy Gene for Diabetic Retinopathy.

Apr 05, 2021

Accumulating evidence suggests the critical role of autophagy in the pathogenesis of diabetic retinopathy (DR). In the current study, we aim to identify autophagy genes involved in DR via microarray a...

Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell-Derived RPE.

Apr 05, 2021

RPE injury often induces epithelial to mesenchymal transition (EMT). Although RPE-EMT has been implicated in a variety of retinal diseases, including proliferative vitroretinopathy, neovascular and at...

Uveitis-Glaucoma-Hyphema Syndrome: Clinical Features and Differential Diagnosis.

Apr 05, 2021

to study the clinical features of uveitis-glaucoma-hyphema (UGH) syndrome, particularly those useful for a differential diagnosis from unilateral hypertensive acute anterior uveitis. A retrospective ...

Systemic Genotype-Phenotype Analysis of MYOC Variants Based on Exome Sequencing and Literature Review.

Apr 05, 2021

This study aims to characterize disease-causing variants in the myocilin gene (MYOC), which is associated with autosomal dominant primary open-angle glaucoma (adPOAG).Case-control study.MYOC variants ...

Characterizing and quantifying the temporal relationship between structural and functional change in glaucoma.

Apr 05, 2021

To characterize and quantify the temporal relationship between structural and functional change in glaucoma.120 eyes of 120 patients with ocular hypertension or primary open-angle glaucoma were select...

Medical History, Clinical Features, Treatment Outcome and Its Predictors Among Infectious Keratitis Patients in Jimma University Medical Center, Southwest Ethiopia: Prospective Observational Study.

Apr 05, 2021

Infectious keratitis is a major global cause of visual impairment and irreversible blindness among the corneal diseases. Its diagnosis and management remain getting challenge. The clinical and visual ...

Reevaluating the Association of Sex With ABCA4 Alleles in Patients With Stargardt Disease.

Apr 05, 2021

Probing differences in disease prevalence between sexes is challenging, especially in mendelian diseases. Independent replication of any association study is warranted.To evaluate whether the recently...

The effect of diabetic retinopathy on standing posture during optic flow stimulation.

Apr 01, 2021

Diabetic retinopathy is a principal cause of visual damage and blindness, in which laser treatment offers proven therapy. The progressive degeneration of the retina, secondary to diabetes, is believed...

Gene Therapy Reforms Photoreceptor Structure and Restores Vision in NPHP5-associated Leber Congenital Amaurosis.

Apr 01, 2021

The inherited childhood blindness caused by mutations in NPHP5, a form of Leber congenital amaurosis, results in abnormal development, dysfunction and degeneration of photoreceptors. A naturally occur...

ROP screening and treatment in four district-level special newborn care units in India: a cross-sectional study of screening and treatment rates.

Apr 01, 2021

Blindness from retinopathy of prematurity (ROP) in middle-income countries is generally due to absence of screening or inadequate screening. The objective of this study was to assess uptake of service...

Parameters of Capsulorrhexis and Intraocular Lens Decentration After Femtosecond and Manual Capsulotomies in High Myopic Patients With Cataracts.

Apr 01, 2021

To compare the parameters of capsulorrhexis and intraocular lens decentration after femtosecond laser capsulotomy and manual continuous curvilinear capsulorrhexis in high myopic patients with catarac...

The Impact of Error of Refraction and Retinal Nerve Fiber Layer Thickness on Cognitive Functions in Adults with Bilateral Myopia.

Apr 01, 2021

Myopia is considered one of the main causes of visual impairment with increased prevalence. The main objective of this study was to evaluate and characterize cognitive impairment in adult patients wi...

Comparison of corneal aberrations and refractive outcomes after small-incision lenticule extraction and femtosecond-assisted laser-assisted in situ keratomileusis.

Apr 01, 2021

To retrospectively compare the short-term refractive outcomes and corneal aberrations after small-incision lenticule extraction (SMILE) and femtosecond-assisted laser-assisted in situ keratomileusis (...

The Effect of Market Competition on the Price of Topical Eye Drops.

Apr 01, 2021

To describe the relationship between the number of Federal Drug Administration (FDA)-approved manufacturers and the price change of generic and branded topical eye drops.Retrospective analysis of topi...

Meibum lipid composition in type 2 diabetics with dry eye.

Apr 01, 2021

The purpose of this investigation was to analyze and compare the composition of meibum between type 2 diabetics with dry eye disease (DED) and control subjects to better reveal the pathologic mechanis...

Automated Image Alignment for Comparing Microvascular Changes Detected by Fluorescein Angiography and Optical Coherence Tomography Angiography in Diabetic Retinopathy.

Apr 01, 2021

To quantitatively compare microvascular features in the macula of patients with diabetic retinopathy (DR) using fluorescein angiography (FA) and optical coherence tomography angiography (OCTA).Patient...

Risk factors associated with diabetic neuropathy in Mexican patients.

Apr 01, 2021

Diabetic neuropathy (DN) is one of the most common complications of type 2 diabetes (T2D) and is a leading cause of lower limb amputation. The aim of the present study was to evaluate the risk factors...