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Ophthalmology General

Arteritic anterior ischaemic optic neuropathy: An update.

Apr 26, 2021

Ischaemic optic neuropathy (ION) is a major cause of blindness. The clinical approach and management is a matter of debate for the treating neurologist and the ophthalmologist. Of the two broad variet...

Intra- and interobserver concordance of a new classification system for myopic maculopathy.

Apr 26, 2021

Myopic maculopathy (MM) is one of the major causes of visual impairment and irreversible blindness in eyes with pathologic myopia (PM). However, the classification of each type of lesion associated wi...

Artificial intelligence-based nomogram for small-incision lenticule extraction.

Apr 26, 2021

Small-incision lenticule extraction (SMILE) is a surgical procedure for the refractive correction of myopia and astigmatism, which has been reported as safe and effective. However, over- and under-cor...

Sleep and subjective happiness between the ages 40 and 59 in relation to presbyopia and dry eye.

Apr 26, 2021

The aim of this study was to explore the status of quality of life between the ages 40-59 in relation to presbyopia and dry eye.Near add power and preferred contact lens power were examined in 219 par...

Prospective trial of a 2940 nm Er:YAG laser for the treatment of meibomian gland dysfunction.

Apr 26, 2021

The primary objective was to evaluate the efficacy and safety of Er:YAG laser treatment for meibomian gland dysfunction (MGD) in a prospective study.A total of 128 eyes from 64 patients with MGD were ...

Malfunction of outer retinal barrier and choroid in the occurrence and progression of diabetic macular edema.

Apr 26, 2021

Diabetic macular edema (DME) is the most common cause of vision loss in diabetic retinopathy, affecting 1 in 15 patients with diabetes mellitus (DM). The disruption of the inner blood-retina barrier (...

The risk of micro and macrovascular disease in Egyptian patients with diabetes and peripheral arterial disease.

Apr 26, 2021

: The aim of this study was to assess the prevalence of micro- and macrovascular disease in Egyptian patients with diabetes mellitus (DM) and peripheral arterial disease (PAD). : The study included 16...

Transthyretin affects the proliferation and migration of human retinal microvascular endothelial cells in hyperglycemia via hnRNPA2B1.

Apr 26, 2021

Transthyretin (TTR) has been proved to repress neovascularization in diabetic retinopathy environment by regulating the molecules in and downstream of the STAT-4/miR-223-3p/FBXW7 signal pathway; howev...

The influence of axial myopia on optic disc characteristics of glaucoma eyes.

Apr 26, 2021

This study characterizes differences in glaucomatous eyes with and without high axial myopia using custom automated analysis of OCT images. 452 eyes of 277 glaucoma patients were stratified into non (...

Anterior versus posterior endoscopic cyclophotocoagulation: comparison of indications, populations, and outcomes.

Apr 26, 2021

To examine how indications, patient characteristics, and outcomes differ between anterior and posterior approaches of endoscopic cyclophotocoagulation (ECP) in the treatment of glaucoma.This is a retr...

Donor demographics and factors affecting corneal utilisation in Eye Bank of North India.

Apr 26, 2021

Nearly 6.8 million people in India have vision less than 6/60 in at least one eye due to corneal diseases; of these, about a million had bilateral involvement.To identify the challenges faced; the tre...

Racial/Ethnic Disparities in Ophthalmology Clinical Trials Resulting in US Food and Drug Administration Drug Approvals From 2000 to 2020.

Apr 26, 2021

Diverse, representative enrollment in pivotal clinical trials is vital to sufficiently power subgroup analyses and ensure equity and validity of trial results.To evaluate the racial/ethnic representat...

Citizen science with colour blindness: A case study on the Forel-Ule scale.

Apr 22, 2021

Many citizen science projects depend on colour vision. Examples include classification of soil or water types and biological monitoring. However, up to 1 in 11 participants are colour blind. We simula...

Identification of patient benefit from proton beam therapy in brain tumour patients based on dosimetric and NTCP analyses.

Apr 22, 2021

The limited availability of proton beam therapy (PBT) requires individual treatment selection strategies, such as the model-based approach. In this study, we assessed the dosimetric benefit of PBT com...

Gene network analyses unveil possible molecular basis underlying drug-induced glaucoma.

Apr 22, 2021

Drug-induced glaucoma (DIG) is a kind of serious adverse drug reaction that can cause irreversible blindness. Up-to-date, the molecular mechanism of DIG largely remains unclear yet due to the medical ...

Coadministration With Carbidopa Enhances the Antimyopic Effects of Levodopa in Chickens.

Apr 22, 2021

Topical application of levodopa inhibits the development of form-deprivation myopia (FDM) and lens-induced myopia (LIM) in chicks. Here we examine whether coadministration with carbidopa enhances this...

Corneal thickness changes in myopic children during and after short-term orthokeratology lens wear.

Apr 22, 2021

To evaluate thickness changes in the central and mid-peripheral cornea (CCT and mPCT), corneal epithelium (CET and mPET) and stroma (CST and mPST) of myopic children during and after short-term orthok...

Protective effects of sunlight exposure against PRK-induced myopia in infant rhesus monkeys.

Apr 22, 2021

Extensive clinical evidence suggests that time spent outdoors might reduce the risk of myopia. This study aimed to determine whether increasing sunlight exposure has a protective effect on hyperopic-d...

Animal Models of Dry Eye: Their Strengths and Limitations for Studying Human Dry Eye Disease.

Apr 22, 2021

Dry eye disease (DED), also called the keratoconjunctivitis sicca (KCS), is one of the most common diseases in the ophthalmology clinics. While DED is not a life-threatening disease, life quality may ...

Dry eye signs and symptoms in patients on aromatase inhibitor therapy.

Apr 22, 2021

The study aimed to test whether symptomatic dry eye in aromatase inhibitor (AI) patients is associated with the clinical features of evaporative dry eye.A cross-sectional, observational study of postm...