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Ophthalmology General

Corneal neuropathic pain in irritable bowel syndrome: clinical findings and in vivo corneal confocal microscopy.

Jul 01, 2021

Ocular discomfort is a common symptom in central sensitization syndromes. The aim of this study was to evaluate ocular surface discomfort and related corneal changes in patients with irritable bowel s...

Mucin-Like Glycoproteins Modulate Interfacial Properties of a Mimetic Ocular Epithelial Surface.

Jul 01, 2021

Dry eye disease (DED) has high personal and societal costs, but its pathology remains elusive due to intertwined biophysical and biochemical processes at the ocular surface. Specifically, mucin defici...

Probabilistic Forecasting of Anti-VEGF Treatment Frequency in Neovascular Age-Related Macular Degeneration.

Jul 01, 2021

To probabilistically forecast needed anti-vascular endothelial growth factor (anti-VEGF) treatment frequency using volumetric spectral domain-optical coherence tomography (SD-OCT) biomarkers in neovas...

Emerging roles of exosomal miRNAs in diabetes mellitus.

Jul 01, 2021

Exosomes are small extracellular vesicles 40-160 nm in diameter that are secreted by almost all cell types. Exosomes can carry diverse cargo including RNA, DNA, lipids, proteins, and metabolites. Exo...

Safety and Efficacy of Intravitreal Risuteganib for Non-Exudative AMD: A Multicenter, Phase 2a, Randomized, Clinical Trial.

Jul 01, 2021

To evaluate the safety and efficacy of 1.0 mg risuteganib in subjects with nonexudative age-related macular degeneration (AMD).This was a phase 2a, prospective, double-masked, sham-controlled study. E...

Comparison of long-term surgical outcomes for scleral-fixated verses retropupillary iris-claw intraocular lens.

Jul 01, 2021

To compare the clinical features and long-term treatment outcomes of patients undergoing secondary intraocular lens (IOL) surgery with scleral-fixated (SFIOL) versus retropupillary iris-claw IOL (RPIC...

Trabeculectomy with Mitomycin-C in Post-Traumatic Angle Recession Glaucoma in Phakic Eyes With no Prior Intraocular Intervention.

Jul 01, 2021

: To evaluate the outcomes of primary trabeculectomy with mitomycin-C (trab MMC) in phakic eyes with post-traumatic angle recession glaucoma with no prior intraocular surgeries.: We included 32 phakic...

Outcomes of Management of Glaucoma in Phacomatosis Pigmentovascularis over the last three decades: a single-center experience.

Jul 01, 2021

To report the clinical outcomes of glaucoma management in patients with phacomatosis pigmentovascularis (PPV) treated over a period of three decades.Retrospective cohort study.Fifty-five eyes of 38 pa...

Homeopathic Agents or Vitamins in Reducing Ecchymosis after Oculofacial Surgery: A Report by the American Academy of Ophthalmology.

Jul 01, 2021

To review the published literature to determine the efficacy and safety of homeopathic agents or vitamins in reducing ecchymosis after oculofacial surgery or laser surgery.A literature search was cond...

Botulinum Toxin Injection for the Treatment of Strabismus: A Report by the American Academy of Ophthalmology.

Jul 01, 2021

To review the available evidence comparing the effectiveness of extraocular muscle botulinum toxin type A (BTXA) injection with eye muscle surgery for restoring ocular alignment in children and adults...

Prevalence, indications and demographic characteristics of Botulinum neurotoxin use in a tertiary oculoplastic centre.

Jul 01, 2021

Over the past 40 years, Botulinum Neurotoxin (BoNT) treatment has been used in many presentations to the hospital eye service. There is little published on its practice in an ophthalmology setting. We...

A Novel Hierarchical Deep Learning Framework for Diagnosing Multiple Visual Impairment Diseases in the Clinical Environment.

Jun 28, 2021

Early detection and treatment of visual impairment diseases are critical and integral to combating avoidable blindness. To enable this, artificial intelligence-based disease identification approaches ...

Multi-scale approach for the prediction of atomic scale properties.

Jun 28, 2021

Electronic nearsightedness is one of the fundamental principles that governs the behavior of condensed matter and supports its description in terms of local entities such as chemical bonds. Locality a...

related Congenital Stationary Night Blindness in Two Siblings due to Probable Maternal Germline Mosaicism.

Jun 28, 2021

: Congenital Stationary Night Blindness (CSNB) is a clinically and genetically heterogenous inherited retinal disorder associated with nystagmus, myopia, strabismus, defective dark adaptation, and dec...

Toric Intraocular Lens Calculation considering anterior Surgically Induced Astigmatism and Posterior Corneal Astigmatism.

Jun 28, 2021

to evaluate the prediction error (PE) after applying the Abulafia-Koch formula in an online calculator with and without consideration of anterior corneal surgically induced astigmatism (SIA).SIA model...

Ocular Surface Changes in Patients with Thyroid Eye Disease: An Observational Clinical Study.

Jun 28, 2021

This study aimed to compare ocular surface parameter changes in active and inactive thyroid eye disease (TED) patients and controls.This is an observational clinical study that included 60 eyes divide...

Effects of Topical Gabapentin on Ocular Pain and Tear Secretion.

Jun 28, 2021

Neuropathic ocular pain is a frequent occurrence in medium to severe dry eye disease (DED). Only palliative treatments, such as lubricants and anti-inflammatory drugs, are available to alleviate patie...

The effects of caffeic acid phenethyl ester on retina in a diabetic rat model.

Jun 28, 2021

We aimed to investigate the effect of caffeic acid phenethyl ester (CAPE) on retinal apoptosis and oxidative stress parameters in streptozotocin (STZ) induced diabetic rat model.This study included 3 ...

Gene Set Enrichment Analyses Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy.

Jun 28, 2021

To identify functionally related genes associated with diabetic retinopathy (DR) risk using gene set enrichment analyses (GSEA) applied to genome-wide association study (GWAS) meta-analyses.We analyze...

Development and Validation of a Preference-Based Glaucoma Utility Instrument Using Discrete Choice Experiment.

Jun 28, 2021

A glaucoma-specific instrument for estimating utilities across the spectrum of glaucoma severity is currently lacking, hindering the assessment of the cost-effectiveness of glaucoma treatments.To deve...

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