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Ophthalmology General

Modified Danzhi Xiaoyao Powder (MDXP) improves the corneal damage in dry eye disease (DED) mice through phagocytosis.

Dec 11, 2023

Modified Danzhi Xiaoyao Powder (MDXP) is a traditional Chinese medicine formula remedy for treating Dry Eye Disease (DED). It showed the function of dispersing stagnated liver Qi for relieving Qi stag...

Exosomes derived from BMSCs alleviates high glucose-induced diabetic retinopathy via carrying miR-483-5p.

Dec 11, 2023

Diabetic retinopathy (DR) is a progressive disease which can cause health problem. It has been reported that bone marrow mesenchymal stem cells (BMSCs)-secreted exosomes could regulate the progression...

Advanced platelet-rich fibrin promotes healing of induced corneal ulcer in donkeys (Equus asinus).

Dec 11, 2023

Ulcerative keratitis is a common disease in horses which may cause blindness. To prevent secondary bacterial and fungal infections and promote quick re-growth of the epithelial layer, different treatm...

Central Visual Field Testing in Early Glaucoma: A Report by the American Academy of Ophthalmology.

Dec 11, 2023

To evaluate the current published literature on the utility of the 10-2 visual field (VF) testing strategy for the evaluation and management of early glaucoma, defined here as mean deviation (MD) bett...

Aqueous Shunts with Extraocular Reservoir for Open-Angle Adult Glaucoma: A Report by the American Academy of Ophthalmology.

Dec 11, 2023

To evaluate the recently published literature on the efficacy and safety of the use of aqueous shunts with extraocular reservoir for the management of adult open-angle glaucomas (OAGs).A search of pee...

Ocular morbidity among children (aged 6-18 yr) of the tribal area of Melghat, India: A community-based study.

Nov 27, 2023

Most of the ocular morbidities among school children are preventable or treatable. Melghat, a difficult to access, hilly, forest, tribal area with poorly developed infrastructure in the Amravati distr...

Treatment of Dry Eye Disease (DED) in Asia: Strategies for Short Tear Film Breakup Time-Type DED.

Nov 27, 2023

Dry eye disease (DED) is a multifactorial disorder in which tear fluid homeostasis is lost, resulting in increased tear film osmolarity and ocular surface irritation. In Asia, the short tear film brea...

Single-Cell Transcriptome Sequencing Unveils Unveils Proinflammatory Microenvironment in Dry Eye Disease

Nov 27, 2023

Dry eye disease (DED) is a prevalent chronic eye disease characterized by an aberrant inflammatory response in ocular surface mucosa. The immunological alterations underlying DED remain largely unknow...

Connection Exists Between Neovascular Age-Related Macular Degeneration & Neurodegenerative Disorders

Nov 27, 2023

Neovascular age-related macular degeneration (nAMD) is a leading cause of irreversible visual impairment in the elderly. The current management of nAMD is limited and involves regular intravitreal adm...

Novel Role of Molecular Hydrogen: The End of Ophthalmic Diseases?

Nov 27, 2023

Molecular hydrogen (H) is a colorless, odorless, and tasteless gas which displays non-toxic features at high concentrations. H can alleviate oxidative damage, reduce inflammatory reactions and inhibit...

Arterial spin labeling reveals disordered cerebral perfusion and cerebral blood flow-based functional connectivity in primary open-angle glaucoma.

Nov 27, 2023

Primary open-angle glaucoma (POAG) is a widespread neurodegenerative condition affecting brain regions involved in visual processing, somatosensory processing, motor control, emotional regulation and ...

Incidence of primary open angle glaucoma in the Andhra Pradesh Eye Disease Study (APEDS).

Nov 27, 2023

To report 15-year incidence rate of primary open angle glaucoma (POAG) in the Andhra Pradesh Eye Disease Study (APEDS).A population-based longitudinal study was carried out at three rural study sites....

[Effectiveness and interest of retrobulbar hyaluronidase injections in the treatment of blindness complicating facial hyaluronic acid injections: A literature review].

Nov 20, 2023

Hyaluronic acid injections are becoming increasingly common among both the general public and the medical community, but they are not without risks. The occurrence of blindness, although rare, is a tr...

High myopia is protective against diabetic retinopathy in the participants of the National Health and Nutrition Examination Survey.

Nov 20, 2023

To investigate the association of subjects with refractive error and diabetic retinopathy (DR) in the United States comparing results between different race groups.All data were derived from National ...

Exploration of the pathophysiology of high myopia via proteomic profiling of human corneal stromal lenticules.

Nov 20, 2023

This study aimed to investigate the underlying pathophysiology of high myopia by analyzing the proteome of human corneal stromal lenticule samples obtained through small incision lenticule extraction ...

The potential benefits of polyphenols for corneal diseases.

Nov 20, 2023

The cornea functions as the primary barrier of the ocular surface, regulating temperature and humidity while providing protection against oxidative stress, harmful stimuli and pathogenic microorganism...

Recent advances in age-related meibomian gland dysfunction (ARMGD).

Nov 20, 2023

Meibomian glands (MGs), located within the tarsal plate of the eyelid, secrete meibum which is the lipid-rich secretion necessary for stabilizing the tear film and preventing tear evaporation. Changes...

Intravitreal anti-vascular endothelial growth factor injections in pregnancy and breastfeeding: a case series and systematic review of the literature.

Nov 20, 2023

Anti-vascular endothelial growth factor (anti-VEGF) agents may occasionally need to be considered for sight-threatening macular pathology in pregnant and breastfeeding women. This is controversial due...

Developing screening tools to estimate the risk of diabetic kidney disease in patients with type 2 diabetes mellitus.

Nov 20, 2023

Diabetic kidney disease (DKD) is an important microvascular complication of diabetes mellitus (DM).This study aimed to develop predictive nomograms to estimate the risk of DKD in patients with type 2 ...

Nationwide analysis of neuromyelitis optica in systemic lupus erythematosus and Sjogren's syndrome.

Nov 20, 2023

Neuromyelitis optica (NMO), also known as Devic's disease, is a rare inflammatory demyelinating disorder causing myelitis and optic neuritis. While there have been reports of systemic lupus erythemato...