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Ophthalmology General

Nitric Oxide Interaction with the Eye.

Jul 05, 2021

Nitric oxide (NO) is acknowledged as a vital intercellular messenger in multiple systems in the body. Medicine has focused on its functions and therapeutic applications for decades, especially in card...

Real-World Anti-Vascular Endothelial Growth Factor Therapy Outcomes in Myopic Choroidal Neovascularization.

Jul 05, 2021

Evaluation of real-world outcomes of intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy in the primary treatment of choroidal neovascularization (CNV) secondary to pathological m...

Autologous serum compared to artificial tear drops for dry eye disease.

Jul 05, 2021

Dry eye is one of the most common ocular surface disorders. Although artificial tear drops therapy is the most widely used treatment, it has recently been suggested that autologous serum could be a be...

Fecal Microbial Transplant in Individuals with Immune-mediated Dry Eye.

Jul 05, 2021

To evaluate the safety of Fecal Microbial Transplant (FMT) in individuals with immune-mediated dry eye (DE).Open-label, non-randomized clinical trial.Ten individuals with DE symptoms and signs meeting...

Sjögren's syndrome in children: about 15 cases in Guinea Conakry.

Jul 05, 2021

Sjögren's syndrome is rare in children and most often secondary. It frequently affects girls and is characterized by dry eye syndrome, mouth and sometimes systemic involvement. Its diagnosis is diffi...

Photoreceptor cell calcium dysregulation and calpain activation promote pathogenic photoreceptor oxidative stress and inflammation in prodromal diabetic retinopathy.

Jul 05, 2021

In this study, we test the hypothesis that diabetes promotes a greater than normal cytosolic calcium level in rod cells that activates a Ca-sensitive protease, calpain, resulting in oxidative stress a...

Intraocular fluid biomarkers (liquid biopsy) in human diabetic retinopathy.

Jul 05, 2021

This article aims to review the impact of detecting and quantifying intraocular biomarkers (liquid biopsy) in both aqueous and vitreous humor in eyes of people affected by diabetes mellitus.This is a ...

Cytoskeleton-associated protein 2 (CKAP2) is regulated by vascular endothelial growth factor and p53 in retinal capillary endothelial cells under high-glucose conditions.

Jul 05, 2021

We previously found the mutation frequency of cytoskeleton-associated protein 2 (CKAP2) was significantly increased in proliferative diabetic retinopathy (PDR) patients through whole exome sequencing....

Prevalence of primary open angle glaucoma in the last 20 years: a meta-analysis and systematic review.

Jul 05, 2021

Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness in the world and is influenced by various sociodemographic factors. This meta-analysis aims to determine the worldwide p...

Colour Doppler imaging of retrobulbar circulation in different severity of glaucoma optic neuropathy.

Jul 05, 2021

To compare retrobulbar hemodynamic measured by colour Doppler imaging (CDI) in patients with a different severity of glaucoma and to correlate variables CDI with the structural parameters of the retin...

Predictive models of aging of the human eye based on ocular anterior segment morphology.

Jul 05, 2021

Aging is a major risk factor for various eye diseases, such as cataract, glaucoma, and age-related macular degeneration. Age-related changes are observed in almost all structures of the human eye. Con...

The American Glaucoma Society 100: Articles with Significant Impact on Clinical Glaucoma Care.

Jul 05, 2021

To identify 100 articles with significant impact on the clinical care of patients with glaucoma.Cross-sectional study.108 members of the American Glaucoma Society (AGS) in the original survey and 63 i...

Five-year review of ocular Neisseria gonorrhoeae infections presenting to ophthalmology departments in Greater Glasgow & Clyde, Scotland.

Jul 05, 2021

As gonococcal infections continue to increase, we wanted to review the number and clinical course of recent ocular gonococcal cases presenting to ophthalmology departments in NHS Greater Glasgow and C...

Prevalence, Patterns, and Characteristics of Eye Injuries in Professional Mixed Martial Arts.

Jul 05, 2021

To describe the frequency and type of eye injuries in fighters in mixed martial arts (MMA) competition.Fight result data were collected from the Nevada Athletic Commission database from 2001 to 2020. ...

TPC2 promotes choroidal angiogenesis and inflammation in a mouse model of neovascular age-related macular degeneration.

Jul 01, 2021

Age-related macular degeneration (AMD) is the most common cause of blindness among the elderly and can be classified either as dry or as neovascular (or wet). Neovascular AMD is characterized by a str...

Automated segmentation of macular edema for the diagnosis of ocular disease using deep learning method.

Jul 01, 2021

Macular edema is considered as a major cause of visual loss and blindness in patients with ocular fundus diseases. Optical coherence tomography (OCT) is a non-invasive imaging technique, which has bee...

Cationic Polyelectrolyte Nanocapsules of Moxifloxacin for Microbial Keratitis Therapy: Development, Characterization, and Pharmacodynamic Study.

Jul 01, 2021

Microbial keratitis (MK) is a vision-threatening disease and the fourth leading cause of blindness worldwide. In this work, we aim to develop moxifloxacin (MXN)-loaded chitosan-based cationic mucoadhe...

Centration of myopic refractive ablation: should we center treatment on the pupil or the visual axis?

Jul 01, 2021

The purpose of this study is to compare pupil versus corneal vertex-centered ablation for myopic laser refractive surgery. This study is a retrospective case series of right eyes of consecutive myopi...

Regional analysis of segmented-macular structure in patients with myopic anisometropia.

Jul 01, 2021

To compare intraretinal layers between the eyes in patients with myopic anisometropia, and evaluate the relationship between the layers with spherical equivalent (SE) and axial length (AL).In this ret...

Towards transforming community eye care: an observational study and time-series analysis of optometrists' prescribing for eye disorders.

Jul 01, 2021

This study aimed to provide evidence on the therapeutic prescribing activity by community optometrists in Scotland and to determine its impact on workload in general practice and ophthalmology clinics...