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Ophthalmology General

Diagnostic circulating biomarkers to detect vision-threatening diabetic retinopathy: Potential screening tool of the future?

Jul 19, 2021

With the increasing prevalence of diabetes in developing and developed countries, the socio-economic burden of diabetic retinopathy (DR), the leading complication of diabetes, is growing. Diabetic ret...

Efficacy and durability of multifactorial intervention on mortality and MACEs: a randomized clinical trial in type-2 diabetic kidney disease.

Jul 19, 2021

Multiple modifiable risk factors for late complications in patients with diabetic kidney disease (DKD), including hyperglycemia, hypertension and dyslipidemia, increase the risk of a poor outcome. DKD...

Eye disease and mortality, cognition, disease, and modifiable risk factors: an umbrella review of meta-analyses of observational studies.

Jul 19, 2021

Globally, 2.2 billion people live with some form of vision impairment and/or eye disease. To date, most systematic reviews examining associations have focused on a single eye disease and there is no s...

Gout and open-angle glaucoma risk in a veteran population.

Jul 19, 2021

A history of gout, arthritis due to hyperuricemia, has been associated with decreased risk for neurodegenerative diseases such as Parkinson's disease. We performed a population-based case-control stud...

Predicting the onset of myopia in children: results from the CLEERE study.

Jul 19, 2021

Research often attempts to identify risk factors associated with prevalent disease or that change the probability of developing disease. These factors may also help in predicting which individuals may...

Endophthalmitis rate in immediately sequential vs delayed sequential bilateral cataract surgery within the IRIS® Registry data.

Jul 19, 2021

To compare the rate of postoperative endophthalmitis following immediately sequential bilateral cataract surgery (ISBCS) vs delayed sequential bilateral cataract surgery (DSBCS) using the American Aca...

Clinical applications for intraoperative optical coherence tomography: a systematic review.

Jul 19, 2021

In this systematic review, we provide an overview of the current state of intraoperative optical coherence tomography (iOCT). As iOCT technology is increasingly utilized, its current clinical applicat...

Clinical Impact of Heritable Thrombophilia on Neonatal-Onset Thromboembolism: A Nationwide Study in Japan.

Jul 12, 2021

To clarify the incidence and genetic risk of neonatal-thromboembolism, we conducted a nationwide study exploring the impact of thrombophilia on neonatal-thromboembolism in Japan.A questionnaire survey...

Adenosine: The common target between cancer immunotherapy and glaucoma in the eye.

Jul 12, 2021

Adenosine, an endogenous purine nucleoside, is a well-known actor of the immune system and the inflammatory response both in physiologic and pathologic conditions. By acting upon particular, G-protein...

Artificial Intelligence-Assisted Early Detection of Retinitis Pigmentosa - the Most Common Inherited Retinal Degeneration.

Jul 12, 2021

The purpose of this study was to detect the presence of retinitis pigmentosa (RP) based on color fundus photographs using a deep learning model. A total of 1670 color fundus photographs from the Taiwa...

Smartphone use associated with refractive error in teenagers; the Myopia app Study.

Jul 12, 2021

To investigate the association between smartphone use and axial length and refractive error in teenagers using the Myopia app.Cross-sectional population-based study.A total of 525 teenagers aged 12 to...

Clinical Applications of In Vivo Confocal Microscopy in Keratorefractive Surgery.

Jul 12, 2021

To review the contribution of in vivo confocal microscopy (IVCM) to the understanding of corneal wound healing following refractive surgery, and its role in the diagnosis and management of complicatio...

Etiology of epiphora.

Jul 12, 2021

This study aimed to analyze the common causes of epiphora in Korean patients and their response to subsequent management.We retrospectively analyzed the medical records of 180 patients who visited Kim...

Evaluation of dry eye and Meibomian gland dysfunction in female androgenetic alopecia patients.

Jul 12, 2021

To evaluate dry eye tests and Meibomian gland functions in female androgenetic alopecia patients.Twenty left eyes of 20 female androgenetic alopecia patients (Group 1) and 20 left eyes of 20 healthy f...

Evaluation of standard of care intravitreal aflibercept treatment of diabetic macular oedema treatment-naive patients in the UK: DRAKO study 12-month outcomes.

Jul 12, 2021

DRAKO (NCT02850263) is a 24-month, prospective, non-interventional, multi-centre cohort study which enroled patients diagnosed with centre-involving diabetic macular oedema (DMO). The study aims to ev...

Choroidal vascular structures in diabetic patients: a meta-analysis.

Jul 12, 2021

Choroidal vascular structures are likely to be affected in diabetic patients. The aim of this study was to conduct a meta-analysis of choroidal vascular structures in diabetic eyes with no diabetic re...

Modeling the Biomechanics of the Lamina Cribrosa Microstructure in the Human Eye.

Jul 12, 2021

Glaucoma is among the leading causes of blindness worldwide that is characterized by irreversible damage to the retinal ganglion cell axons in the lamina cribrosa (LC) region of the optic nerve head (...

Outcomes of Ahmed glaucoma valve implantation in eyes with pediatric keratoplasty.

Jul 12, 2021

This study aimed to assess the efficacy and safety of Ahmed glaucoma valve (AGV) implantation in eyes with pediatric keratoplasty and glaucoma.Retrospective, non-comparative, interventional case serie...

Application of 5G Technology to Conduct Real-Time Teleretinal Laser Photocoagulation for the Treatment of Diabetic Retinopathy.

Jul 12, 2021

Interest in teleophthalmology has been growing, especially during the COVID-19 pandemic. The advent of fifth-generation (5G) wireless systems has the potential to revolutionize teleophthalmology, but ...

Local anaesthesia as a standard of care for penetrating keratoplasty?

Jul 12, 2021

To determine preferences in the use of local anaesthesia (LA) versus general anaesthesia (GA) for penetrating keratoplasty (PK), and to examine the safety of LA for PK.A retrospective analysis of PKs ...