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Ophthalmology General

Efficacy of Artificial Intelligence-based Screening for Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients.

Jan 17, 2022

To explore the efficacy of artificial intelligence (AI)-based screening for diabetic retinopathy (DR) in type 2 diabetes mellitus (T2DM) patients.Data were obtained from 549 T2DM patients who visited ...

Proteomic changes of aqueous humor in proliferative diabetic retinopathy patients treated with different intravitreal anti-VEGF agents.

Jan 17, 2022

Anti-VEGF-based treatment have been regularly used in recent years in proliferative diabetic retinopathy (PDR) patients. However, some of these patients fail to respond effectively to anti-VEGF. Given...

Role and mechanism(s) of incretin-dependent therapies for treating diabetes mellitus.

Jan 17, 2022

Diabetes mellitus (DM) is a worldwide ailment which leads to chronic complications like cardiac disorders, renal perturbations, limb amputation and blindness. Type one diabetes (T1DM), Type two diabet...

Dermatological adverse effects of anti-glaucoma eye drops: a review.

Jan 17, 2022

Many patients are treated for glaucoma. Like other drugs, anti-glaucoma eye drops may induce dermatological adverse effects. We aim to review the dermatological adverse effects secondary to the active...

Evaluation of Artificial Intelligence-Based Intraoperative Guidance Tools for Phacoemulsification Cataract Surgery.

Jan 17, 2022

Complications that arise from phacoemulsification procedures can lead to worse visual outcomes. Real-time image processing with artificial intelligence tools can extract data to deliver surgical guida...

Visual Field Loss Impacts Vision-Specific Quality of Life by Race, Ethnicity: The Multiethnic Ophthalmology Cohorts of California Study.

Jan 17, 2022

To assess the impact of Visual Field Loss (VFL) on Vision-Specific Quality of Life (VSQOL) by race, ethnicity and age DESIGN: Pooled analysis of cross-sectional data from three population-based, prosp...

Arguments for 'ocular donation' as standardised terminology to reduce the 'ick factor' of 'eye donation'.

Jan 10, 2022

This brief report presents the global problem of the shortfall of donor corneal tissue for transplantation, a potential root cause ('ick factor' language), and a potential solution (modification of 'i...

Evaluation of peripapillary - macular microvascularity and choroidal vascularity index after refractive surgery.

Jan 10, 2022

To evaluate the microvascularity and choroidal vascularity index (CVI) using optical coherence tomography angiography (OCTA) and OCT following femtosecond laser-assisted in-situ keratomileusis (FS-LAS...

Effect of preoperative keratometry on visual outcomes after small-incision lenticule extraction for myopia.

Jan 10, 2022

To investigate the relationship between preoperative keratometry (K) and postoperative refraction and compare the visual outcomes after small-incision lenticule extraction (SMILE) between preoperative...

Scleral Lens and Prosthetic Replacement of the Ocular Surface Ecosystem Utilization in Ocular Graft-versus-Host Disease: A Survey Study.

Jan 10, 2022

To evaluate the utilization of scleral lenses and prosthetic replacement of the ocular surface ecosystem devices (SL/PDs) in the management of ocular graft-versus-host disease (oGVHD).A survey of 15 q...

Assessment of meibomian gland drop-out and visibility through a new quantitative method in scleral lens wearers: A one-year follow-up study.

Jan 10, 2022

To validate a previously developed algorithm based on the visibility of meibomian gland images obtained with Cobra fundus camera and to assess the changes in meibomian glands in scleral lens wearers o...

Deep CNN with Hybrid Binary Local Search and Particle Swarm Optimizer for Exudates Classification from Fundus Images.

Jan 10, 2022

Diabetic retinopathy is a chronic condition that causes vision loss if not detected early. In the early stage, it can be diagnosed with the aid of exudates which are called lesions. However, it is ard...

The association between serum interleukin-1 beta and heparin sulphate in diabetic nephropathy patients.

Jan 10, 2022

Inflammation is considered an important mechanism in the development of diabetes mellitus (DM) and persists for a long time before the occurrence of diabetic nephropathy (DN). Many studies have demons...

Functional assays of non-canonical splice-site variants in inherited retinal dystrophies genes.

Jan 10, 2022

Inherited retinal dystrophies are a group of disorders characterized by the progressive degeneration of photoreceptors leading to loss of the visual function and eventually to legal blindness. Althoug...

Visual Outcomes Associated With Patterns of Macular Edema Resolution in Central Retinal Vein Occlusion Treated With Anti-Vascular Endothelial Growth Factor Therapy: A Post Hoc Analysis of the Lucentis, Eylea, Avastin in Vein Occlusion (LEAVO) Trial.

Jan 10, 2022

It is unclear how visual outcomes vary between patterns of macular edema (ME) resolution in eyes with central retinal vein occlusion (CRVO).To assess best-corrected visual acuity (BCVA) outcomes at 10...

Stabilization of refractive error and associated factors following small incision phacoemulsification cataract surgery.

Jan 10, 2022

Accumulating evidence suggests that refractive stabilization occurs rapidly following small incision cataract surgery. Nonetheless, many guidelines still suggest waiting four to 6 weeks before prescri...

Group identity in blindness groups predicts life satisfaction and lower anxiety and depression.

Jan 03, 2022

Group disability identity (GDI) refers to feelings of connection to the disability community. Researchers have proposed that disability identity protects against disability-related stressors. However,...

Decreased Choroidal Blood Perfusion Induces Myopia in Guinea Pigs.

Jan 03, 2022

The development of myopia in guinea pigs can be inhibited by attenuating scleral hypoxia by increasing choroidal blood perfusion (ChBP). In this study, we reduced ChBP through surgical and pharmacolog...

Characterization of the thickness of the Tear Film Lipid Layer in Meibomian Gland Dysfunction using high resolution optical microscopy.

Jan 03, 2022

To evaluate the thickness of the tear film lipid layer (TFLL) in meibomian gland dysfunction (MGD) using a high-resolution optical microscope.The Ocular Surface Disease Index (OSDI) and meibum grade s...

The link module of human TSG-6 (Link_TSG6) promotes wound healing, suppresses inflammation and improves glandular function in mouse models of Dry Eye Disease.

Jan 03, 2022

To investigate the potential of the Link_TSG6 polypeptide comprising the Link module of human TSG-6 (TNF-stimulated gene/protein-6) as a novel treatment for dry eye disease (DED). We analyzed the the...

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