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Ophthalmology General

Effects of intensive insulin therapy on the retinal microvasculature in patients with type 2 diabetes mellitus: a prospective observational study.

Apr 25, 2022

We examined the retinal microvascular changes and associated factors in type 2 diabetes mellitus (T2DM) before and after intensive insulin therapy.This prospective observational study recruited patien...

Generation of 3D retinal tissue from human pluripotent stem cells using a directed small molecule-based serum-free microwell platform.

Apr 25, 2022

Retinal degenerative diseases are a leading cause of blindness worldwide with debilitating life-long consequences for the affected individuals. Cell therapy is considered a potential future clinical i...

Novel and investigational therapies for wet and dry age-related macular degeneration.

Apr 25, 2022

Age-related macular degeneration (AMD) is a macular degenerative eye disease, the major cause of irreversible loss of central vision. In this review, we highlight current progress and future perspecti...

Plasma Levels of Bevacizumab and Vascular Endothelial Growth Factor After Low-Dose Bevacizumab Treatment for Retinopathy of Prematurity in Infants.

Apr 25, 2022

Intravitreal bevacizumab effectively treats severe retinopathy of prematurity (ROP), but it enters the bloodstream and may reduce serum vascular endothelial growth factor (VEGF), potentially causing d...

Atypical Visual Field Asymmetries in Redundancy Masking

Apr 22, 2022

The lowering of the apparent number of components in repeated patterns is known as redundancy masking. It has a lot of traits with crowding, which is defined as the inability to identify a goal in a c...

Equivalent Noise Characterization of Human Lightness Constancy

Apr 20, 2022

Visual perception's purpose is to generate consistent representations of task-relevant scene features (e.g., object reflectance) despite fluctuation in task-irrelevant scene variables (e.g. illuminati...

Open Perimetry Initiative: A Cross-Platform Development For The New Generation of Portable Perimeters

Apr 20, 2022

The Open Perimetry Initiative was established in 2010 with the goal of lowering obstacles to clinical research using visual fields and perimetry. The Open Perimetry Interface (OPI) and the visual fiel...

The Economic Burden of Vision Loss (VL) & Blindness in the US

Apr 20, 2022

For a study, researchers sought to calculate the economic impact of vision loss (VL) in the United States, state by state. Secondary data sources (American Community Survey [ACS], American Time Use Su...

Familiarity, Orientation, & Realism Increase Face Uncanniness By Sensitizing To Facial Distortions

Apr 20, 2022

The uncanny valley foreshadows negative reactions to near-humanlike beings. Distortions in realistic faces evoked more uncanniness than distortions in artificial ones, presumably due to familiarity. T...

Weighting the Factors Affecting Attention Guidance During Free Viewing and Visual Search

Apr 20, 2022

For decades, researchers have examined the elements that influence how attention is directed during visual tasks, but few studies attempted to quantify the weighting of multiple of these aspects insid...

What are the VisuoMotor Tendencies of Omnidirectional Scene Free-Viewing in Virtual Reality?

Apr 20, 2022

On two-dimensional displays, central and peripheral vision during visual tasks have been widely investigated, showing perceptual and functional differences. For a study, researchers sought to: recreat...

Wedge Defects on OCTA of the Peripapillary Retina in Glaucoma: Prevalence and Associated Clinical Factors

Apr 19, 2022

For a study, the researchers sought to find the factors influencing wedge deficiencies in peripapillary OCTA in glaucoma. Between 2016 and 2020, 278 eyes of 186 participants with mild to severe primar...

Self-Identified Black Race as a Risk Factor for IOP Elevation & Iritis Following Prophylactic LPI

Apr 19, 2022

For a study, the researchers sought to determine how laser type and patient variables affected the incidence of IOP rise and iritis following LPI in PACS. Between 2010 and 2018, the electronic medical...

Structural Glaucoma Progression Trajectory in 2D Space

Apr 19, 2022

For a study, the researchers sought to present a method for visualizing the glaucomatous change in a 2D S/F space. The structural score was developed using 64 normal and 64 glaucomatous eyes from Grou...

Examination of Macular Retina and Choroidal Thickness in High Myopic Amblyopia Using Spectral-Domain Optical Coherence Tomography.

Apr 18, 2022

The aim of this study was to investigate changes in the retinal and choroidal thickness between high myopic amblyopia (HMA), low myopia (LM), moderate myopia (MM), high myopia (HM), and normal group (...

Transcriptional profiling of the chick retina identifies down-regulation of and genes during early lens-induced myopia.

Apr 18, 2022

Gene expression of the chick retina was examined during the early development of lens-induced myopia (LIM) using whole transcriptome sequencing. Monocular treatment of the right eyes with -10 diopter ...

Prevalence and risk factors for dry eye disease: the Sao Paulo dry eye study.

Apr 18, 2022

To estimate the prevalence and risk factors of dry eye disease symptoms and clinical diagnoses in Sao Paulo city, state of Sao Paulo, Brazil.A total of 582 participants over 18 years old, living in th...

Macular Choroidal Thickness and the Risk of Referable Diabetic Retinopathy in Type 2 Diabetes: A 2-Year Longitudinal Study.

Apr 18, 2022

The purpose of this study was to evaluate the associations between choroidal thickness (CT) and the 2-year incidence of referable diabetic retinopathy (RDR).This was a prospective cohort study. Patien...

Correlation of Complement Activation in Aqueous and Vitreous in Patients With Proliferative Diabetic Retinopathy.

Apr 18, 2022

A growing body of evidence suggests complement dysregulation is present in the vitreous of patients with diabetic eye disease. Further translational study could be simplified if aqueous-as opposed to ...

Ground reaction forces during stair ascending and descending in congenitally blind and sighted individuals.

Apr 18, 2022

Stair ascending and descending are common in daily life activities which are challenging for blind individuals. Visual information plays an important role in controlling an individual's movements. How...