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Ophthalmology General

Impact of keratoconus stage on outcome after corneal crosslinking.

May 09, 2022

This study aimed to analyze if the outcome after corneal crosslinking (CXL) in progressive keratoconus patients depends on the stage at which the procedure is performed. This knowledge would help to i...

Management Strategies for Evaporative Dry Eye Disease and Future Perspective.

May 09, 2022

Dry eye disease (DED) is a common disorder that remains challenging from a clinical perspective. Unstable or deficient tear film is a major factor contributing to DED and the inability to resolve the ...

Optimization of IL-1RA structure to achieve a smaller protein with a higher affinity to its receptor.

May 09, 2022

Interleukine-1 family cytokines are key orchestrators of innate and adaptive immunity. In particular, up-regulation of IL-1R1 via its agonistic ligands consisting of IL-1β and IL-1α is implicated in...

Visual impairment as a predictor for deterioration in functioning: the Leiden 85-plus Study.

May 09, 2022

Visual impairment frequently occurs amongst older people. Therefore, the aim of this study was to investigate the predictive value of visual impairment on functioning, quality of life and mortality in...

Harnessing retinal phagocytes to combat pathological neovascularization in ischemic retinopathies?

May 09, 2022

Ischemic retinopathies (IR) are vision-threatening diseases that affect a substantial amount of people across all age groups worldwide. The current treatment options of photocoagulation and anti-VEGF ...

Elevated TGFβ signaling contributes to ocular anterior segment dysgenesis in Col4a1 mutant mice.

May 09, 2022

Ocular anterior segment dysgenesis (ASD) refers to a collection of developmental disorders affecting the anterior structures of the eye. Although a number of genes have been implicated in the etiology...

White and non-White Australian mental health care practitioners' desirable responding, cultural competence, and racial/ethnic attitudes.

May 09, 2022

Racial, ethnic, religious, and cultural diversity in Australia is rapidly increasing. Although Indigenous Australians account for only approximately 3.5% of the country's population, over 50% of Austr...

Paediatric traumatic cataracts in Southwest China: epidemiological profile.

May 09, 2022

Paediatric traumatic cataracts are an important but preventable cause of acquired blindness. Understanding the epidemiology of paediatric traumatic cataracts is a prerequisite for prevention. This stu...

Predictive factors of posterior corneal shift after small incision lenticule extraction: a 5-year follow-up study.

May 02, 2022

The aim of this study was to determine risk factors affecting changes in posterior corneal elevation (PCE) and predict the 5-year stability after small incision lenticule extraction (SMILE).This retro...

Corneal morphology correlates with choriocapillaris perfusion in myopic children.

May 02, 2022

The present study investigated the difference in choriocapillaris (CC) perfusion between different AL/K ratio groups with similar spherical equivalent refraction (SER) and analyzed factors affecting C...

Effects of systemic anti-androgen drugs on the ocular surface.

May 02, 2022

To investigate the effect of systemic anti-androgen drugs on tear function tests and the ocular surface.Sixty-four male subjects were included in this study. Subjects who were on anti-androgen treatme...

Role of neuroticism and perceived stress on quality of life among patients with dry eye disease.

May 02, 2022

This hospital-based, cross-sectional observational study aimed to examine whether neuroticism has an impact on stress that is related to dry eye disease (DED) and quality of life (QOL). One hundred pa...

Inflammatory cytokines and retinal nonperfusion area in quiescent proliferative diabetic retinopathy.

May 02, 2022

We sought to investigate the association between inflammatory cytokine levels and retinal capillary nonperfusion area in eyes with quiescent proliferative diabetic retinopathy (PDR).Samples of aqueous...

[Features of structural and microvascular changes of the choroid in angioretinopathy of various etiologies].

May 02, 2022

To study structural and microvascular changes in the choroid in patients with chronic kidney disease (CKD), diabetic retinopathy (DR) and arterial hypertension (AH), and their relationship with the le...

Correlation Between Altmetric Attention Scores and Citations for Articles Published in High-Impact Factor Ophthalmology Journals From 2018 to 2019.

May 02, 2022

The Altmetric attention score (AAS) provides new information to gauge the impact of a research article not found through typical metrics, such as impact factor or citation counts.To explore the associ...

Exploring Ocular Adverse Events in Users of PDE5 Inhibitors

Apr 26, 2022

The use of PDE5 inhibitors increases the risk for serous retinal detachment, ischemic optic neuropathy, and retinal vascular occlusion in older men. Phosphodiesterase type 5 (PDE5) inhibitors a...

Method for Film Thickness Mapping with an Astigmatic Optical Profilometer.

Apr 25, 2022

An astigmatic optical profilometer is a precision instrument with advantages such as high resolution, high bandwidth, a compact size, and low cost. However, current astigmatic optical profilometers me...

Screen time and health issues in Chinese school-aged children and adolescents: a systematic review and meta-analysis.

Apr 25, 2022

Many literature reviews summarized relationships between screen time and child health, but they only included a few studies conducted in Chinese children and adolescents. The potential influence of sc...

Viscoelastic properties of the human tear film.

Apr 25, 2022

When considering eye blinking from a tribological perspective, tear viscosity is expected to play a fundamental role. The application of rheological techniques to describe the tear film dates back to ...

The Role of Metalloproteinases and Their Tissue Inhibitors on Ocular Diseases: Focusing on Potential Mechanisms.

Apr 25, 2022

Eye diseases are associated with visual impairment, reduced quality of life, and may even lead to vision loss. The efficacy of available treatment of eye diseases is not satisfactory. The unique envir...