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Ophthalmology General

Ocular microvascular alteration in patients with myocardial infarction-a new OCTA study.

Feb 26, 2024

Myocardial infarction is defined as a sudden decrease or interruption in blood flow to the coronary arteries, causing ischemic necrosis of the corresponding cardiomyocytes. It is unclear whether syste...

Macula vs periphery in diabetic retinopathy: OCT-angiography and ultrawide field fluorescein angiography imaging of retinal non perfusion.

Feb 26, 2024

To investigate the association between peripheral non-perfusion index (NPI) on ultrawide-field fluorescein angiography (UWF-FA) and quantitative OCT-Angiography (OCT-A) metrics in the macula.In total,...

A comparative analysis of IOP measurement accuracy with reused iCare probes.

Feb 26, 2024

To assess the accuracy of reused iCare probes after disinfection with 70% isopropyl alcohol and ethylene glycol compared to new iCare probes and Goldmann Applanation Tonometry (GAT).Prospective compar...

Effectiveness and safety of XEN63 in patients with primary-open-angle glaucoma.

Feb 26, 2024

This paper evaluates the effectiveness and safety of XEN63 stent, either standalone or in combination with phacoemulsification, in patients with primary open-angle glaucoma (POAG). Eighty eyes from 80...

Assessment of a Large Language Model's Responses to Questions and Cases About Glaucoma and Retina Management.

Feb 26, 2024

Large language models (LLMs) are revolutionizing medical diagnosis and treatment, offering unprecedented accuracy and ease surpassing conventional search engines. Their integration into medical assist...

Comparison of early changes in tear film protein profiles after small incision lenticule extraction (SMILE) and femtosecond LASIK (FS-LASIK) surgery.

Feb 19, 2024

Small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (LASIK) are widely used surgical methods to correct myopia with comparable efficacy, predictability, a...

Evaluation of Dry Eye Severity and Ocular Surface Inflammation in Patients with Autoimmune Rheumatic Diseases.

Feb 19, 2024

To evaluate dry eye severity and ocular surface inflammation in autoimmune rheumatic diseases (ARDs).Seventy-nine patients with ARDs were enrolled, including 26 patients with rheumatoid arthritis (RA)...

Resilient back-propagation machine learning-based classification on fundus images for retinal microaneurysm detection.

Feb 19, 2024

The timely diagnosis of medical conditions, particularly diabetic retinopathy, relies on the identification of retinal microaneurysms. However, the commonly used retinography method poses a challenge ...

Epiretinal membrane development after Ex-Press glaucoma filtration device implant: 2-year results of a case control study.

Feb 19, 2024

The most common retinal complications after glaucoma surgery are choroidal detachment, hypotony maculopathy, malignant glaucoma, vitreous hemorrhage, endophthalmitis and retinal detachment. However, i...

Infectious eye disease in the 21st century-an overview.

Feb 19, 2024

Infectious diseases affecting the eye often cause unilateral or asymmetric visual loss in children and people of working age. This group of conditions includes viral, bacterial, fungal and parasitic d...

The role of transforming growth factor beta in myopia development.

Feb 12, 2024

Myopia is widely recognized as an epidemic. Studies have found a link between Transforming Growth Factor-beta (TGF-β) and myopia, but the specific molecular mechanisms are not fully understood. In th...

A novel variant of DNM1L expanding the clinical phenotypic spectrum: a case report and literature review.

Feb 12, 2024

Mitochondrial diseases are heterogeneous in terms of clinical manifestations and genetic characteristics. The dynamin 1-like gene (DNM1L) encodes dynamin-related protein 1 (DRP1), a member of the GTPa...

A Systematic Review of Tear Vascular Endothelial Growth Factor and External Eye Diseases.

Feb 12, 2024

We aim to summarize the current evidence of Vascular endothelial growth factors (VEGF)s in external eye diseases and determine whether serum and plasma VEGF levels are associated with tear and ocular ...

Two-Photon and Multiphoton Microscopy in Anterior Segment Diseases of the Eye.

Feb 12, 2024

Two-photon excitation microscopy (TPM) and multiphoton fluorescence microscopy (MPM) are advanced forms of intravital high-resolution functional microscopy techniques that allow for the imaging of dyn...

PFKFB3 in neovascular eye disease: unraveling mechanisms and exploring therapeutic strategies.

Feb 12, 2024

Neovascular eye disease is characterized by pathological neovascularization, with clinical manifestations such as intraocular exudation, bleeding, and scar formation, ultimately leading to blindness i...

Effect of non-overlapping visual field defects on vision related quality of life in glaucoma.

Feb 12, 2024

Glaucoma patients may be considered to have normal vision as long as each point of visual space is perceived by at least one eye, that is, with an intact binocular visual field. We aimed to investigat...

Geometric transformation adaptive optics (GTAO) for volumetric deep brain imaging through gradient-index lenses.

Feb 05, 2024

The advance of genetic function indicators has enabled the observation of neuronal activities at single-cell resolutions. A major challenge for the applications on mammalian brains is the limited opti...

Extending the Scope of Conceptual Density Functional Theory with Second Order Analytical Methodologies.

Feb 05, 2024

In the context of the growing impact of conceptual density functional theory (DFT) as one of the most successful chemical reactivity theories, response functions up to second order have now been widel...

Characterizing the Robustness of Distinct Clinical Assessments in Identifying Dry Eye Condition of Animal Models.

Feb 05, 2024

The study aims to characterize the robustness of distinct clinical assessments in identifying the underlying conditions of dry eye disease (DED), with a specific emphasis on the involvement of conjunc...

Association between systemic medication use and severity of dry eye signs and symptoms in the DRy eye assessment and management (DREAM) study.

Feb 05, 2024

Some systemic medications are reported to be associated with dry eye disease (DED), yet their associations with the severity of DED signs and symptoms are not well studied. To evaluate these associati...