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Ophthalmology General

A deep network using coarse clinical prior for myopic maculopathy grading.

Jan 23, 2023

Pathological Myopia (PM) is a globally prevalent eye disease which is one of the main causes of blindness. In the long-term clinical observation, myopic maculopathy is a main criterion to diagnose PM ...

Management of Sjogren's Dry Eye Disease-Advances in Ocular Drug Delivery Offering a New Hope.

Jan 23, 2023

Sjögren's syndrome is a chronic and insidious autoimmune disease characterized by lymphocyte infiltration of exocrine glands. Patients typically present with dry eye, dry mouth, and other systemic ma...

Dry eye in primary care: the relationship between digital display device usage and dry eye syndrome (DES) in medical students.

Jan 23, 2023

As digital display devices become more and more indispensable, associated health problems have started to increase. We aimed to investigate the frequency and relationship of digital display device usa...

Barriers and facilitators in the referral pathways to low vision services from the perspective of patients and professionals: a qualitative study.

Jan 23, 2023

Underutilization of and lack of access to low vision services (LVS) has been reported internationally. The purpose of this study was to identify barriers and facilitators in LVS referral procedures an...

Sleep duration and the risk of major eye disorders: a systematic review and meta-analysis.

Jan 23, 2023

To assess the relationship between sleep duration and the risk of major eye disorders including myopia, glaucoma, cataract, age-related macular degeneration (AMD), and diabetic retinopathy (DR).Databa...

Validation of UVEDAI: An Index for Evaluating the Level of Inflammatory Activity in Uveitis.

Jan 23, 2023

Uveitis is the inflammation of the middle layer of the eye, the uvea, and is a major cause of blindness. None of the instruments used in clinical practice are, in themselves, sufficient to evaluate th...

Analysis of Non-vasogenic Cystoid Maculopathies (NVCM)

Jan 20, 2023

The following is the summary of “Non-vasogenic cystoid maculopathies” published in the November 2022 issue of Progress in retinal and eye research by Gaudric, et al. Non-vasogenic cystoid m...

The Mechanism of Retinal Pigmentation in Human Albinism

Jan 20, 2023

The following is the summary of “Retinal pigmentation pathway in human albinism: Not so black and white” published in November 2022 issue of Retinal and eye by Bakker, et al. Albinism is a ...

Visual Restoration Through Optogenetics

Jan 20, 2023

The following is the summary of “Optogenetics for visual restoration: From proof of principle to translational challenges” published in November 2022 issue of Retinal and Eye by  Lindner, et al. ...

A novel biosensing platform for detection of glaucoma biomarker GDF15 via an integrated BLI-ELASA strategy.

Jan 16, 2023

Glaucoma is a leading cause of irreversible blindness worldwide. Early discovery and prioritized intervention significantly impact its prognosis. Precise monitoring of the biomarker GDF15 contributes ...

Photoreceptor laminin drives differentiation of human pluripotent stem cells to photoreceptor progenitors that partially restore retina function.

Jan 16, 2023

Blindness caused by advanced stages of inherited retinal diseases and age-related macular degeneration are characterized by photoreceptor loss. Cell therapy involving replacement with functional photo...

Influence of location, season and time of day on the spectral composition of ambient light: Investigation for application in myopia.

Jan 16, 2023

Given the possible role of spectral composition of light and myopia, this study aimed at investigating the variation in the spectral composition of ambient light in different (a) outdoor/indoor locati...

Preoperative geometric parameters predict the outcome of lamellar keratoscleroplasty in patients with limbal dermoids.

Jan 16, 2023

To find preoperative simple geometric parameters to predict the outcome of lamellar keratoscleroplasty in patients with corneal limbal dermoids.We retrospectively analyzed the data of 30 patients with...

Evaluation of Dry Eye Severity and Ocular Surface Inflammation in Patients with Pemphigus and Pemphigoid.

Jan 16, 2023

To evaluate ocular surface involvement, tear cytokine levels, and histopathological changes in pemphigus and pemphigoid patients.A total of 22 patients (15 pemphigus and 7 pemphigoids) and 21 non-dise...

The protective effect of luteolin on the depression-related dry eye disorder through Sirt1/NF-κB/NLRP3 pathway.

Jan 16, 2023

Luteolin has been reported to exhibit therapeutic effect on depressive-like behaviors in mice. Nevertheless, the therapeutic effect of luteolin on the depression-related dry eye disorder remains incon...

25-hydroxyvitamin D3 inhibits oxidative stress and ferroptosis in retinal microvascular endothelial cells induced by high glucose through down-regulation of miR-93.

Jan 16, 2023

The decrease of vitamin D plays a critical role in diabetes mellitus (DM)-induced oxidative stress and vascular endothelial injury. Therefore, we investigated the effect and mechanism of 25-hydroxyvit...

HIF-1α accumulation in response to transient hypoglycemia may worsen diabetic eye disease.

Jan 16, 2023

Tight glycemic control (TGC), the cornerstone of diabetic management, reduces the incidence and progression of diabetic microvascular disease. However, TGC can also lead to transient episodes of hypog...

An Association between Large Optic Cupping and Total and Regional Brain Volume: The Women's Health Initiative.

Jan 16, 2023

To investigate the relationships between optic nerve cupping and total and regional brain volumes.Secondary analysis of randomized clinical trial data.Women, aged 65 to 79, without glaucoma with cup-t...

The effect of citicoline oral solution on quality of life in patients with glaucoma: the results of an international, multicenter, randomized, placebo-controlled cross-over trial.

Jan 16, 2023

This study aims to evaluate whether the use of citicoline oral solution could improve quality of life in patients with chronic open-angle glaucoma (OAG).Randomized, double-masked, placebo-controlled, ...

Association Between Preresidency Peer-reviewed Publications and Future Academic Productivity or Career Choice Among Ophthalmology Residency Applicants.

Jan 16, 2023

Ophthalmology-residency selection committees require robust metrics to review applicants. Participation in research activities is a core component of the application process for its perceived associat...