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Ophthalmology General

Relationship between Intrinsically Photosensitive Ganglion Cell Function and Circadian Regulation in Diabetic Retinopathy.

Feb 04, 2020

Intrinsically photosensitive retinal ganglion cells (ipRGCs) control non-visual light responses (e.g. pupillary light reflex and circadian entrainment). Patients with diabetic retinopathy (DR) show re...

Retinal Non-Perfusion in Proliferative Diabetic Retinopathy Before and After Panretinal Photocoagulation Assessed by Wide Field OCT Angiography.

Feb 04, 2020

Wide field swept source OCT angiography (WF SS-OCTA) imaging was compared with ultrawide-field (UWF) fluorescein angiography (FA) imaging to better understand changes in retinal non-perfusion before a...

Policy Implications of Artificial Intelligence and Machine Learning in Diabetes Management.

Feb 04, 2020

Machine learning (ML) is increasingly being studied for the screening, diagnosis, and management of diabetes and its complications. Although various models of ML have been developed, most have not led...

Socialising over fruits and vegetables: the biocultural importance of an open-air market in Bandar Seri Begawan, Brunei Darussalam.

Feb 04, 2020

Earth's biocultural diversity comprising biological, cultural and linguistic diversities is being eroded quickly. Our ability to recognise and appreciate what is remaining is crucial for its survival....

Baseline characteristics of participants in the Treatment of Advanced Glaucoma Study (TAGS): A multicentre randomised controlled trial.

Feb 04, 2020

To report the baseline characteristics of participants enrolled in the Treatment of Advanced Glaucoma Study (TAGS) DESIGN: Pragmatic randomised control trial (RCT).Patients with open angle glaucoma pr...

Development of an online digital resource accessible for students with visual impairment or blindness: Challenges and strategies.

Feb 04, 2020

People with visual impairment or blindness face a wide range of daily barriers, both at school and at work.This article describes the development process of an online resource, addressing Occupational...

Clinical analysis of posterior segment injury in left-behind children in China.

Feb 04, 2020

We aimed to evaluate the severity and prognosis of posterior segment injury between left-behind children (LBC) and guarded children (NLBC).A retrospective, controlled analysis of a case series was per...

The Effect of Acute Exercise on Environmentally Induced Symptoms of Dry Eye

Jan 31, 2020

The purpose of this study was to investigate the effects of acute exercise on environmentally induced symptoms of dry eye. Twelve participants without dry eye disease volunteered to complete three exp...

Beneficial effects of saffron ( L.) in ocular pathologies, particularly neurodegenerative retinal diseases.

Jan 31, 2020

Saffron (Crocus sativus L.) has been traditionally used in food preparation and as a medicinal plant. It currently has numerous therapeutic properties attributed to it, such as protection against isch...

Polysaccharides Protects Retinal Ganglion Cells Against Oxidative Stress Injury

Jan 31, 2020

The accumulation of excessive reactive oxygen species can exacerbate any injury of retinal tissue because free radicals can trigger lipid peroxidation, protein damage and DNA fragmentation. Increased ...

Hypothyroidism and Adverse Endpoints in Diabetic Patients

Jan 31, 2020

This study investigated the relationship strength between hypothyroidism and cardiovascular and renal outcomes in diabetic patients. The electronic databases PubMed, EmBase, and Cochrane library wer...

Circulating long noncoding RNAs H19 and GAS5 are associated with type 2 diabetes but not with diabetic retinopathy: A preliminary study.

Jan 31, 2020

Recently, a wide range of biological and pathological roles of long noncoding RNAs (lncRNAs) have been discovered. However, the potential role of circulating lncRNAs H19 and GAS5 in type 2 diabetes me...

Percentage of Youth with Visual Impairments Meeting 24-hr Movement Guidelines

Jan 31, 2020

Recent movement behaviour guidelines prescribe the optimal time spent in physical activity, screen time, and sleep across a 24-hr period. The proportion of youth with visual impairments meeting 0, 1, ...

Motion-induced blindness as a tool to measure attentional biases and the link to attention-deficit/hyperactivity traits.

Jan 31, 2020

Typically, individuals have an attentional bias toward the left visual field. This is often absent in individuals with attention-deficit/hyperactivity (ADH) disorder (ADHD). We used a motion-induced b...

Genetic Heritability of Pigmentary Glaucoma and Associations With Other Eye Phenotypes

Jan 31, 2020

Mechanisms behind pigmentary glaucoma, a form of early-onset glaucoma that may potentially lead to severe visual impairment or blindness, are poorly understood.To calculate the single-nucleotide polym...

Identification of Novel Mutations in the and Genes in Patients with Familial Exudative Vitreoretinopathy in South India.

Jan 31, 2020

Familial exudative vitreoretinopathy (FEVR) is an inheritable retinal vascular disease, which often leads to severe vision loss and blindness in children. However, reported mutations can only account...

A sensitive period in the neural phenotype of language in blind individuals.

Jan 31, 2020

Congenital blindness modifies the neural basis of language: "visual" cortices respond to linguistic information, and fronto-temporal language networks are less left-lateralized. We tested the hypothes...

Design and baseline data of a population-based metabonomics study of eye diseases in eastern China: the Yueqing Ocular Diseases Investigation.

Jan 30, 2020

China is undergoing a massive transition toward an urban and industrial economy. These changes will restructure the demographics and economy which will eventually influence the future patterns of dis...

Survival and ocular preservation in a long-term cohort of Japanese patients with retinoblastoma.

Jan 30, 2020

Retinoblastoma is an ocular tumor in infants with cancer predisposition. Treatment of the rare tumor needs to be optimized for ocular preserved survival without second primary malignancy (SPM).We stud...

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits.

Jan 30, 2020

Dry eye disease (DED) is a complex disease with multiple etiologies and variable symptoms, having ocular surface inflammation as its key pathophysiologic step. Despite advances in our understanding of...

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