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Ophthalmology General

Agreement and repeatability of four different devices to measure non-invasive tear breakup time (NIBUT).

Mar 09, 2020

Since tear film stability can be affected by fluorescein, the Dry Eye Workshop (DEWSII) recommended non-invasive measurement of tear breakup time (NIBUT). The aim of this study was to investigate the ...

The effect of sodium fluorescein on anterior eye surface measurements.

Mar 09, 2020

During image acquisition, certain topographers require the addition of sodium fluorescein (NaFl) dye to the tear film. This study investigates the effect of NaFl dye on corneal topography and tear sur...

Comparison of true-colour wide-field confocal scanner imaging with standard fundus photography for diabetic retinopathy screening.

Mar 09, 2020

Screening of diabetic retinopathy (DR) reduces blindness by early identification of retinopathy. This study compares DR grades derived from a two-field imaging protocol from two imaging platforms, one...

Activation of retinal angiogenesis in hyperglycemic zebrafish mutants.

Mar 09, 2020

Progression from the initial vascular response upon hyperglycemia to a proliferative stage with neovacularizations is the hallmark of proliferative diabetic retinopathy. Here we report on the novel di...

Antagonist of nucleolin, N6L, inhibits neovascularization in mouse models of retinopathies.

Mar 09, 2020

Retinal vascular diseases (RVD) have been identified as a major cause of blindness worldwide. These pathologies, including the wet form of age-related macular degeneration, retinopathy of prematurity,...

Treatment of diabetic retinopathy through neuropeptide Y-mediated enhancement of neurovascular microenvironment.

Mar 09, 2020

Diabetic retinopathy (DR) is one of the most severe clinical manifestations of diabetes mellitus and a major cause of blindness. DR is principally a microvascular disease, although the pathogenesis al...

Association between community outpatient clinic care accessibility and the uptake of diabetic retinopathy screening: A multi-level analysis.

Mar 09, 2020

To investigate the uptake rate variance of fundus examination for diabetes-related complications among demographically and geographically diverse communities and examine determinants that influence th...

The prevalence of uveitis in a population of donkeys in the UK.

Mar 09, 2020

Uveitis is a leading cause of blindness in horses. Little work has been undertaken to investigate whether donkeys are affected by a similar disease prevalence.To investigate the disease prevalence of ...

Lipofilling of the upper eyelid to treat paralytic lagophthalmos.

Mar 09, 2020

Lagophthalmos is one of the most unpleasant and dangerous conditions that affect patients with facial palsy. The lack of ocular protection leads to corneal problems (such as conjunctival infections, a...

Albrecht von Graefe in the present, the past, and the future.

Mar 09, 2020

Albrecht von Graefe (1828-1870) is the founder of this archive (1854) and the founder of modern ophthalmology. In 2020, the anniversary of his death will be observed for the 150th time. The "German Op...

Diagnostic power of scleral spur length in primary open-angle glaucoma.

Mar 09, 2020

To investigate the diagnostic capability of scleral spur length in discriminating eyes with primary open-angle glaucoma (POAG) from healthy eyes.Seventy-eight eyes of 78 patients with POAG and 93 eyes...

Vitrectomy with or without internal limiting membrane peeling for myopic foveoschisis.

Mar 09, 2020

The aim of this study was to compare the anatomical and visual outcomes of vitrectomy with or without internal limiting membrane (ILM) peeling for symptomatic myopic foveoschisis (MF).A retrospective ...

Pediatric ocular trauma: Characteristics and outcomes among a French cohort (2007-2016).

Mar 05, 2020

Pediatric ocular trauma is a major cause of acquired monocular blindness. Post-traumatic visual impairment can lead to significant handicap. In France, recent data on the epidemiology of pediatric ocu...

Validation and reliability of the Turkish version of Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8).

Mar 05, 2020

Contact lens dry eye questionnaire-8 (CLDEQ-8) quantifies the disturbing symptoms with the aim of assessing the satisfaction and overall opinion of contact lens wearers. The aim of this study was to d...

Association between Dry Eye and Depressive Symptoms: Large-Scale Crowdsourced Research Using the DryEyeRhythm iPhone Application.

Mar 05, 2020

Dry eye (DE) disease and depression are increasing in modern times. We investigated the association between DE and depressive symptoms using the iPhone application, DryEyeRhythm.This large-scale crowd...

High-fat diet induces dry eye-like ocular surface damages in murine.

Mar 05, 2020

A high-fat diet leads to dysfunction in multiple systems of the body. Herein we investigate the effects of a high-fat diet on the ocular surface using a murine model.Four-week-old male C57BL/6 mice we...

Management of moderate-to-severe dry eye disease using chitosan-N-acetylcysteine (Lacrimera®) eye drops: a retrospective case series.

Mar 05, 2020

Dry eye disease is a highly prevalent condition that causes tear film instability, ocular discomfort, and visual disturbance. Lacrimera eye drops are approved for the short-term treatment of dry eye d...

Explanatory Model of Dry Eye Disease Using Health and Nutrition Examinations: Machine Learning and Network-Based Factor Analysis From a National Survey.

Mar 05, 2020

Dry eye disease (DED) is a complex disease of the ocular surface, and its associated factors are important for understanding and effectively treating DED.This study aimed to provide an integrative and...

Risk factors for dropped nucleus in cataract surgery as reflected by the European Registry of Quality Outcomes for Cataract and Refractive Surgery.

Mar 05, 2020

To analyze the incidence, risk factors, and outcomes of cataract surgery complicated by a dropped nucleus.Patients who have received cataract surgery in 18 European countries.Retrospective cross-secti...

Health-related quality of life and health utilities in insulin-treated type 2 diabetes: the impact of related comorbidities/complications.

Mar 05, 2020

To evaluate the impact of multiple comorbidities/complications on health-related quality of life (HRQoL) and health utilities in insulin-treated type 2 diabetes (T2DM).In a non-interventional, epidemi...