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Ophthalmology General

Prevalence and causes of visual impairment among older persons living in low-income old age homes in Durban, South Africa.

Jul 09, 2020

Visual impairment (VI) increases with age and has been reported to be more prevalent among older adults living in old age homes than in the general population.To determine the prevalence and causes of...

Mucoadhesive Polysaccharide-Based Artificial Tears to Relieve Symptoms and Inflammation in Rabbit with Dry Eyes Syndrome.

Jul 09, 2020

Dry eye syndrome (DES) is a multifactorial disorder of the ocular surface affecting many people all over the world. However, there have been many therapeutic advancements for the treatment of DES, sub...

The Matthew Effect in Recovery from Smartphone Addiction in a 6-Month Longitudinal Study of Children and Adolescents.

Jul 09, 2020

The clinical course of problematic smartphone use (PSU) remains largely unknown due to a lack of longitudinal studies. We recruited 193 subjects with smartphone addiction problems for the present stud...

Dry Eye Disease after Cataract Surgery: Study of its Determinants and Risk Factors

Jul 09, 2020

To study the incidence of dry eye and its determinants in patients undergoing cataract surgery.One hundred twenty patients with senile cataract underwent Schirmer's test, tear break-up time (TBUT) tes...

Subclinical inner retinal layer thickness changes in the fellow eyes of patients with unilateral central retinal artery occlusion: a pilot study.

Jul 09, 2020

To investigate microstructural changes in the macular inner retinal layers over time in the fellow eyes of patients with unilateral central retinal artery occlusion (CRAO).Spectral-domain optical cohe...

MiR-204 inhibits inflammation and cell apoptosis in retinopathy rats with diabetic retinopathy by regulating Bcl-2 and SIRT1 expressions.

Jul 09, 2020

To explore the influences of micro ribonucleic acid (miR)-204 on the rats with diabetic retinopathy by regulating the expressions of B-cell lymphoma 2 (Bcl-2) and sirtuin 1 (SIRT1).A total of 36 Sprag...

Krukenberg's Spindles Strongly Suggest Long Anterior Zonule Associated Pigment Dispersion Mechanism in Older Patients.

Jul 09, 2020

The purpose of this study was to further investigate factors associated with Krukenberg's spindle (KS) presence in a primary eye care setting.As part of a larger investigation, several practitioners i...

Intravitreal enzyme replacement inhibits progression of retinal degeneration in canine CLN2 neuronal ceroid lipofuscinosis.

Jul 09, 2020

CLN2 neuronal ceroid lipofuscinosis is a rare recessive hereditary retinal and neurodegenerative disease resulting from deleterious sequence variants in TPP1 that encodes the soluble lysosomal enzyme ...

Retinal pigment epithelium transcriptome analysis in chronic smoking reveals a suppressed innate immune response and activation of differentiation pathways.

Jul 09, 2020

Cigarette smoking, a powerful mixture of chemical oxidants, is the strongest environmental risk factor for developing age-related macular degeneration (AMD), the most common cause of blindness among t...

Blau syndrome: NOD2-related systemic autoinflammatory granulomatosis.

Jul 06, 2020

Blau syndrome, or early-onset sarcoidosis, is hereditary juvenile-onset systemic granulomatosis. Clinical symptoms appear before the age of 4 years and mainly affect the skin, joints, and eyes. The sy...

Protecting the Ocular Surface in Cataract Surgery: The Efficacy of the Perioperative Use of a Hydroxypropyl Guar and Hyaluronic Acid Ophthalmic Solution.

Jul 06, 2020

To evaluate the effects of a hydroxypropyl guar (HPG) and hyaluronic acid (HA) ophthalmic solution in terms of post-cataract surgery dry-eye disease (DED) prevention.In this retrospective study, the d...

Evaluation of objective visual quality in dry eye disease and corneal nerve changes.

Jul 06, 2020

To explore objective visual quality in dry eye diseases (DED) and the correlation between corneal nerves and objective visual quality.Ninety-eight eyes of 49 patients with DED were included. Each pati...

Optical quality in patients with dry eye before and after treatment.

Jul 06, 2020

Dry eye disease could result in vision-related subjective symptoms even in patients with good best-corrected visual acuity. The standard deviation of corneal power and the surface asymmetry index coul...

Hybrid machine learning architecture for automated detection and grading of retinal images for diabetic retinopathy.

Jul 06, 2020

: Diabetic retinopathy is the leading cause of blindness, affecting over 93 million people. An automated clinical retinal screening process would be highly beneficial and provide a valuable second op...

TIR generated by Continuous Glucose Monitoring is associated with peripheral nerve function in type 2 diabetes.

Jul 06, 2020

Continuous glucose monitoring (CGM)-derived time-in-range (TIR) of 3.9-10 mmol/L is associated with diabetic retinopathy in type 2 diabetes (T2DM), but its relationship to peripheral nerve function ha...

PPARα activation directly upregulates thrombomodulin in the diabetic retina.

Jul 06, 2020

Two large clinical studies showed that fenofibrate, a commonly used peroxisome proliferator-activated receptor α (PPARα) agonist, has protective effects against diabetic retinopathy. However, the un...

Metabolic Syndrome is Associated with Ocular Hypertension and Glaucoma.

Jul 06, 2020

Glaucoma remains the world's leading cause of irreversible blindness and though intraocular pressure (IOP) is the most prevalent risk factor and only reliable therapeutic target, a number of systemic ...

[Clinical and genetic analysis of a patient with rare nephronophthisis].

Jul 06, 2020

To explore the genetic basis for a child with clinically suspected nephronophthisis (NPHP).Peripheral blood samples of the patient and her parents were collected subjected to high-throughput sequencin...

Long-term outcomes of Descemet membrane endothelial keratoplasty in eyes with prior glaucoma surgery.

Jul 06, 2020

To evaluate the long-term outcomes of Descemet membrane endothelial keratoplasty (DMEK) in eyes with prior trabeculectomy and/or drainage device.Retrospective, noncomparative case series.Medical recor...

Incidence, characteristics, outcomes and confidence in managing posterior capsular rupture during cataract surgery in the UK: an ophthalmology trainees' perspective.

Jul 06, 2020

To examine the incidence, characteristics and outcomes of posterior capsular rupture (PCR) cases amongst the ophthalmology trainees and to evaluate the trainees' confidence in managing PCR.A two-stage...