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Ophthalmology General

The Effect of Blue-Light Filtering Intraocular Lenses on the Development and Progression of Neovascular Age-related Macular Degeneration.

Jul 30, 2020

To assess the effect of blue-light filtering (BLF) intraocular lenses (IOL) on the prevention of neovascular AMD (nAMD) following cataract surgery.Cohort study.Patients who underwent uneventful catara...

The Effect of Dietary Vitamin K1 Supplementation on Trabecular Meshwork and Retina in a Chronic Ocular Hypertensive Rat Model.

Jul 30, 2020

The pathophysiologic relationship between vitamin K and glaucoma remains largely unknown. The aim of the study was to explore the effect of dietary vitamin K supplementation in a rat glaucoma model.Ra...

Cumulative deamidations of the major lens protein γS-crystallin increase its aggregation during unfolding and oxidation.

Jul 27, 2020

Age-related lens cataract is the major cause of blindness worldwide. The mechanisms whereby crystallins, the predominant lens proteins, assemble into large aggregates that scatter light within the len...

THE CURRENT STATUS OF BIOLOGICAL TREATMENT FOR UVEITIS.

Jul 27, 2020

Noninfectious uveitis represents one of the leading causes of blindness in developed Countries, compromising patients' quality of life and social functioning. The main treatment goals are the control ...

The use of topical cyclosporine A 0.05% as treatment for primary alacrimia in Allgrove syndrome.

Jul 27, 2020

The purpose is to report a case on the use of cyclosporine A 0.05% for primary alacrimia in Allgrove syndrome or triple A syndrome (alacrimia, achalasia, and adrenal insufficiency).A 37-year-old man w...

The Early Effects of Alcohol Consumption on Functional Visual Acuity, Tear Functions, and the Ocular Surface.

Jul 27, 2020

We investigated the early effects of alcohol intake on tear functions and ocular surface health in this prospective controlled study.Forty-four eyes of 22 subjects (17 males, 5 females; mean age: 35.3...

Transient tear hyperosmolarity disrupts the neuroimmune homeostasis of the ocular surface and facilitates dry eye onset.

Jul 27, 2020

Dry eye disease (DED) is a highly prevalent ocular surface disorder with neuroimmune pathophysiology. Tear hyperosmolarity (THO), a frequent finding in affected patients, is considered a key element i...

Risk factors for non-diabetic renal disease in diabetic patients.

Jul 27, 2020

Diabetic patients with kidney disease have a high prevalence of non-diabetic renal disease (NDRD). Renal and patient survival regarding the diagnosis of diabetic nephropathy (DN) or NDRD have not been...

Isoliquiritigenin downregulates miR-195 and attenuates oxidative stress and inflammation in STZ-induced retinal injury.

Jul 27, 2020

Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus that leads to significant vision loss. Isoliquiritigenin (ISL) is a bioactive flavonoid found in the root of licori...

Evaluation of retinal neurovascular structures by optical coherence tomography and optical coherence tomography angiography in children and adolescents with type 1 diabetes mellitus without clinical sign of diabetic retinopathy.

Jul 27, 2020

The aim of the study was to investigate whether retinal neurovascular structural impairment in children and adolescents with type 1 diabetes mellitus (T1D) without clinical signs of diabetic retinopat...

Differences in outflow channels between two eyes of unilateral primary congenital glaucoma.

Jul 27, 2020

Primary congenital glaucoma (PCG) occurs in only one eye in some patients. We aimed to characterize anatomical features of the angle and Schlemm's canal (SC) in vivo among fellow eyes of patients with...

Predictive factors of Boston Type I Keratoprosthesis outcomes: A long-term analysis.

Jul 27, 2020

To study the long-term visual- and device retention-related outcomes and complications of the Boston Type I Keratoprosthesis (KPro).Single-center, retrospective cohort study of all patients undergoing...

Primary endoscopic management of apoplexy in a giant pituitary adenoma.

Jul 27, 2020

Sellar lesions with large suprasellar extension represent a neurosurgical challenge because of their nature and anatomical complexity. The goal of the extended transphenoidal-transtuberculum approach ...

Ophthalmic Technology Assessment - Sentinel Lymph Node Biopsy for Eyelid and Conjunctival Malignancy: A report by the American Academy of Ophthalmology.

Jul 27, 2020

To determine the efficacy and safety of sentinel lymph node biopsy (SLNB) in the management of eyelid and conjunctival malignancy.A literature search was performed in August 2019 and January 2020 for ...

Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model.

Jul 23, 2020

Age-related macular degeneration (AMD) is a chronic, multifactorial disorder and a leading cause of blindness in the elderly. Characterized by progressive photoreceptor degeneration in the central ret...

Resilience, anxiety and depression, coping style, social support and their correlation in parents of premature infants undergoing outpatient fundus examination for retinopathy of prematurity.

Jul 23, 2020

Retinopathy of prematurity (ROP) has become the main cause of blindness in children. To study resilience, anxiety and depression, coping style and social support and their correlation in parents of pr...

Retinal Glial and Choroidal Vascular Pathology in Donors Clinically Diagnosed With Stargardt Disease.

Jul 23, 2020

The present study investigated retinal glia and choroidal vessels in flatmounts and sections from individuals with clinically diagnosed Stargardt disease (STGD).Eyes from three donors clinically diagn...

Effect of natural extract eye drops in dry eye disease rats.

Jul 23, 2020

To investigate the therapeutic effect of natural extract eye drops containing bee venom, musk, and deer antlers in dry eye disease (DED) animal models.Scopolamine-injected DED rats and lacrimal gland-...

Metabolomic analysis in ophthalmology.

Jul 23, 2020

Modern science takes into account phenotype complexity and establishes approaches to track changes on every possible level. Many "omics" studies have been developed over the last decade. Metabolomic a...

Ocular Demodex: a systematic review of the clinical literature.

Jul 23, 2020

There is increasing clinical and research interest in the potential contribution of Demodex to ocular surface disease. The aim of this systematic review was to summarise and synthesise current clinica...