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Ophthalmology General

High density lipoproteins are a potential therapeutic target for age-related macular degeneration.

Aug 03, 2020

Strong evidence suggests that dysregulated lipid metabolism involving dysfunction of the retinal pigmented epithelium (RPE) underlies the pathogenesis of age-related macular degeneration (AMD), the le...

Gender Specific Differences in Signs and Symptoms of Dry Eye Disease.

Aug 03, 2020

Dry Eye Disease (DED) is a multifactorial disease of the ocular surface characterized by loss of homeostasis of the tear film. Epidemiological studies suggest it occurs more frequently in women than m...

NLRP12- and NLRC4-mediated corneal epithelial pyroptosis is driven by GSDMD cleavage accompanied by IL-33 processing in dry eye.

Aug 03, 2020

Dry eye disease (DED) is a common and multifactor-induced autoimmune ocular surface disease. Environmental factors, such as desiccating stress (DS) and hyperosmolarity, affect the corneal epithelium t...

Efficacy and retention of silicone punctal plugs for treatment of dry eye in patients with and without ocular graft-versus-host-disease.

Aug 03, 2020

To examine the retention rates and efficacy of silicone punctal plugs for the treatment of dry eye disease (DED) in patients with ocular graft-versus-host-disease (oGVHD) in comparison to dry eye dise...

Aspirin in a diabetic retinopathy setting: Insights from NO BLIND study.

Aug 03, 2020

Diabetic retinopathy (DR) is the most common microvascular complication of diabetes. Diabetic macroangiopathies, particularly cardiovascular (CV) diseases, seem closely related to diabetes microvascul...

Circulating Metabolites and Lipids are Associated to Diabetic Retinopathy in Individuals With Type 1 Diabetes.

Aug 03, 2020

Omics based methods may provide new markers associated to diabetic retinopathy (DR). We investigated a wide omics panel of metabolites and lipids related to DR in type 1 diabetes. Metabolomic analyses...

Long-term outcomes of therapeutic penetrating keratoplasty for microbial keratitis in a tertiary care center in Turkey.

Aug 03, 2020

To present the long-term results of therapeutic keratoplasty for microbial keratitis in moderate to advanced phases.The medical records of 44 patients who underwent therapeutic keratoplasty for microb...

The photopic negative response (PhNR): measurement approaches and utility in glaucoma.

Aug 03, 2020

Visual electrophysiological testing continues to generate interest among glaucoma experts because of its potential help in clarifying disease pathophysiology and promoting early detection of glaucomat...

The Effectiveness of Intracameral Moxifloxacin Endophthalmitis Prophylaxis for Trabeculectomy.

Aug 03, 2020

The effect of intracameral (IC) moxifloxacin prophylaxis in preventing acute post-operative endophthalmitis, a rare but potentially visually devastating surgical complication, remains unstudied for gl...

Recent theranostic paradigms for the management of Age-related macular degeneration.

Jul 30, 2020

Degenerative diseases of eye like Age-related macular degeneration (AMD), that affects the central portion of the retina (macula), is one of the leading causes of blindness worldwide especially in the...

[New evidence on the protector effect of weight gain in retinopathy of prematurity].

Jul 30, 2020

Retinopathy of prematurity (ROP) is characterised by insufficient vascular development in the retina, and requires early treatment to avoid visual disability in severe cases. ROP is currently the seco...

Does Blindness Boost Working Memory? A Natural Experiment and Cross-Cultural Study.

Jul 30, 2020

Intelligence requires sufficient working-memory capacity. Traditionally, working memory was seen as a process and as a prerequisite for fluid intelligence. Working memory was assumed to be determined ...

Meibomian glands structure in daily disposable soft contact lens wearers: a one-year follow-up study.

Jul 30, 2020

To assess the impact of daily disposable soft contact lenses on meibomian gland morphology over a period of 12 months.Forty-one subjects (33 experienced and 8 neophytes) were fitted with either silic...

Assessing the ocular surface microbiome in severe ocular surface diseases.

Jul 30, 2020

There is growing evidence for a critical role of the microbiome in ocular health and disease. We performed a prospective, observational study to characterize the ocular surface microbiome (OSM) in fou...

Strategies of upper blepharoplasty in aging patients with involutional ptosis.

Jul 30, 2020

In many aging individuals, dermatochalasis and involutional ptosis appear together. Therefore, for functional and aesthetic purposes, ptosis correction and upper blepharoplasty are performed together....

Molecular Assessment of Epiretinal Membrane: Activated Microglia, Oxidative Stress and Inflammation.

Jul 30, 2020

Fibrocellular membrane or epiretinal membrane (ERM) forms on the surface of the inner limiting membrane (ILM) in the inner retina and alters the structure and function of the retina. ERM formation is ...

Synthesis and Biomedical Potential of Azapeptide Modulators of the Cluster of Differentiation 36 Receptor (CD36).

Jul 30, 2020

The innovative development of azapeptide analogues of growth hormone releasing peptide-6 (GHRP-6) has produced selective modulators of the cluster of differentiation 36 receptor (CD36). The azapeptide...

New Insights Into Immunological Therapy for Retinal Disorders.

Jul 30, 2020

In the twentieth century, a conspicuous lack of effective treatment strategies existed for managing several retinal disorders, including age-related macular degeneration; diabetic retinopathy (DR); re...

Clinical outcomes of Ankoris toric intraocular lens implantation using a computer-assisted marker system.

Jul 30, 2020

To report the clinical outcomes of patients who underwent cataract surgery with implantation of Ankoris monofocal toric intraocular lens (IOL) (PhysIOL SA, Liège, Belgium) using the Zeiss Callisto Ey...

Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial.

Jul 30, 2020

Retinal ganglion cells endure significant metabolic stress in glaucoma but maintain capacity to recover function. Nicotinamide, a precursor of NAD , is low in serum of glaucoma patients and its supple...

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