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Ophthalmology General

MiR-542-5p regulates the progression of diabetic retinopathy by targeting CARM1.

Sep 03, 2020

Diabetic retinopathy (DR), as the most frequent microvascular complication of diabetes mellitus (DM), causes vision loss and blindness in adults worldwide with increasing incidence. MicroRNAs (miRNAs)...

Research article miR-21-5p: A viable therapeutic strategy for regulating intraocular pressure.

Sep 03, 2020

Lowering intraocular pressure (IOP) is the most effective treatment of glaucoma, however most of the current available glaucoma drugs target a single molecule. MicroRNAs (miRNAs) are noncoding RNAs th...

Progression and Risk Factors of Nongeographic Atrophy

Sep 02, 2020

Nongeographic atrophy (NGA) refers to as the retinal pigment disturbances, including hyperpigmentation and hypopigmentation in CFPs. NGA can be caused in eyes treated with anti-vascular endothelial gr...

Gender Gap in Ophthalmology Conference Speakers

Sep 01, 2020

“Although the rates of women in medicine and ophthalmology are increasing, a gender gap still exists in senior positions, such as senior faculty, chairs of academic programs, and deans of medical sc...

Non-Physician Hospital CEO Cut after Participating in Surgery

Aug 31, 2020

Last week on Twitter I asked this question: The 130 (2.5%) of 5,213 respondents who said they would allow a CEO to make a skin incision highlight the unscientific nature of Twitter polls. Restr...

Prevalence and Risk Factors of Severe Dry Eye in Bangladesh-Based Factory Garment Workers.

Aug 31, 2020

This study sought to evaluate the prevalence of dry eye and meibomian gland dysfunction (MGD) and the associated factors of severe dry eye symptoms (SDES) among garments worker of Gazipur, Bangladesh....

Size of the associations between anticholinergic burden tool scores and adverse outcomes in older patients.

Aug 31, 2020

Background Several anticholinergic scales and equations to evaluate the anticholinergic burden have been previously created. Association of these instruments with the anticholinergic outcomes are usua...

Efficacy and tolerability of nortriptyline in the management of neuropathic corneal pain.

Aug 31, 2020

Neuropathic corneal pain (NCP) is a recently acknowledged disease entity. However, there is no consensus in potential treatment strategies, particularly in patients with a centralized component of pai...

Comparison of SDOCT Scan Types for Grading Disorganization of Retinal Inner Layers and Other Morphologic Features of Diabetic Macular Edema.

Aug 31, 2020

To assess grading reproducibility of disorganization of the retinal inner layers (DRIL) and other morphologic features of diabetic macular edema (DME) across spectral domain optical coherence tomograp...

Patterns and Determinants of Choroidal Thickness in a Multiethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study.

Aug 31, 2020

To describe the distribution and determinants of choroidal thickness (CT) in participants in a population study based on spectral-domain optical coherence tomography (SD-OCT) measurements.Population-b...

Improved conjunctival microcirculation in diabetic retinopathy patients with MTHFR polymorphisms after Ocufolin™ Administration.

Aug 31, 2020

To investigate conjunctival microvascular responses in patients with mild diabetic retinopathy (MDR) and methylenetetrahydrofolate reductase (MTHFR) polymorphisms (D+PM) after administration of Ocufol...

Blindness Following Carotid Artery Stenting Due to Ocular Hyperperfusion - Report and Review of Literature.

Aug 31, 2020

Cerebral hyperperfusion syndrome is a well-recognised phenomenon following carotid revascularisation. It is defined as cerebral blood flow increase of more than 100% of the baseline. A similar phenome...

RNA-Seq analysis of differentially expressed genes of Staphylococcus epidermidis isolated from postoperative endophthalmitis and the healthy conjunctiva.

Aug 31, 2020

Staphylococcus epidermidis (S. epidermidis) is one of the primary pathogens in postoperative endophthalmitis, which is a devastating complication of cataract surgery and often results in irreversible ...

The X-linked retinopathies: Physiological insights, pathogenic mechanisms, phenotypic features and novel therapies.

Aug 31, 2020

X-linked retinopathies represent a significant proportion of monogenic retinal disease. They include progressive and stationary conditions, with and without syndromic features. Many are X-linked reces...

Retinal Manifestations of Idiopathic Intracranial Hypertension.

Aug 31, 2020

Case series and systematic review to understand significant retinal changes in patients with idiopathic intracranial hypertension (IIH) using fundus photography and optical coherence tomography (OCT)....

Alpha-crystallin mutations alter lens metabolites in mouse models of human cataracts.

Aug 27, 2020

Cataracts are a major cause of blindness worldwide and commonly occur in individuals over 70 years old. Cataracts can also appear earlier in life due to genetic mutations. The lens proteins, αA- and ...

Reproduction Function in Male Patients with Bardet Biedl Syndrome.

Aug 27, 2020

Bardet-Biedl syndrome (BBS) is a ciliopathy with a wide spectrum of symptoms due to primary cilia dysfunction including genitourinary developmental anomalies as well as impaired reproduction particula...

Long non-coding RNA MEG3 promotes cataractogenesis by upregulating TP53INP1 expression in age-related cataract.

Aug 27, 2020

Age-related cataract (ARC) is the leading cause of visual impairment or even blindness among the aged population globally. Long non-coding RNA (LncRNA) has been proven to be the potential regulator of...

Do Head-Mounted Augmented Reality Devices Affect Muscle Activity and Eye Strain of Utility Workers Who Do Procedural Work? Studies of Operators and Manhole Workers.

Aug 27, 2020

The objective was to determine the effect of two head-mounted display (HMD) augmented reality (AR) devices on muscle activity and eye strain of electric utility workers. The AR devices were the Micros...

Study of Factors Influencing Dry Eye in Rheumatoid Arthritis.

Aug 27, 2020

The present study investigated the relationship between dry eye and the disease activity in patients with rheumatoid arthritis (RA).Patients with RA were divided by the Ocular Surface Disease Index (O...