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Ophthalmology General

Novel Insights into Beta 2 Adrenergic Receptor Function in the rd10 Model of Retinitis Pigmentosa.

Sep 14, 2020

: In retinitis pigmentosa (RP), inherited rod death is followed by cone loss and blindness. Why cones die is still a matter of consideration. Here, we investigate the pathogenic role of the sympatheti...

LiQD Cornea: Pro-regeneration collagen mimetics as patches and alternatives to corneal transplantation.

Sep 14, 2020

Transplantation with donor corneas is the mainstay for treating corneal blindness, but a severe worldwide shortage necessitates the development of other treatment options. Corneal perforation from inf...

CHARGE syndrome without colobomas: Ophthalmic findings.

Sep 14, 2020

To report ophthalmic findings of patients without colobomas, and with a clinical and molecular diagnosis of CHARGE Syndrome. Retrospective study of ophthalmic findings in 67 CHARGE patients-clinically...

2D fourier transform for global analysis and classification of meibomian gland images.

Sep 14, 2020

In recent years, significant progress has been made in the Meibography technique resulting from the use of advanced image analysis methods allowing a quantitative description of the Meibomian gland st...

Effects of the re-esterified triglyceride (rTG) form of omega-3 supplements on dry eye following cataract surgery.

Sep 14, 2020

To evaluate the clinical outcomes of the systemic re-esterified triglyceride (rTG) form of omega-3 fatty acids in patients with dry eye symptoms after cataract surgery.This prospective comparative coh...

Automated vessel density detection in fluorescein angiography images correlates with vision in proliferative diabetic retinopathy.

Sep 14, 2020

To investigate the correlation between quantifiable vessel density, computed in an automated fashion, from ultra-widefield fluorescein angiography (UWFFA) images from patients with proliferative diabe...

Current use of the automatic retinal oximetry. Review.

Sep 14, 2020

To inform about possible use of the automatic retinal oximetry for the retinal oxygen saturation measurement in the eye and systemic diseases.We performed a literature review dealing with issues of r...

Geometric Perfusion Deficits: A Novel OCT Angiography Biomarker for Diabetic Retinopathy Based on Oxygen Diffusion.

Sep 14, 2020

To develop geometric perfusion deficits (GPD), an optical coherence tomography angiography (OCTA) biomarker based on oxygen diffusion, and to evaluate its utility in a pilot study of healthy subjects ...

Bleb plication: a minimally invasive repair method for a leaking ischemic bleb after trabeculectomy.

Sep 14, 2020

Bleb leakage is a serious complication of glaucoma filtering surgery. This study describes the method and the results of a new repair method for ischemic bleb leaks. The subjects were consecutive elev...

Conjunctival thickness as a predictive imaging biomarker for the glaucoma filtration surgery outcome: An optical coherence tomography study.

Sep 14, 2020

To analyze the pre-operative conjunctival thickness in glaucomatous patients undergoing filtration surgery (FS), using optical coherence tomography (OCT).The conjunctival status represents one of the ...

Impact of Socioeconomic Disadvantage and Diabetic Retinopathy Severity on Poor Ophthalmic Follow-Up in a Rural Vermont and New York Population.

Sep 14, 2020

To investigate the impact of socioeconomic disadvantage and diabetic retinopathy severity on follow-up for vision care among people with diabetes mellitus (DM) residing in rural Vermont and northern N...

Influence of automated visual field testing on intraocular pressure.

Sep 14, 2020

To evaluate the influence of automated visual field (VF) testing on intraocular pressure (IOP) in patients with ocular hypertension (OHT) or glaucoma.We conducted a prospective observational study in ...

Host cell death during infection with Chlamydia: a double-edged sword.

Sep 10, 2020

The phylum Chlamydiae constitutes a group of obligate intracellular bacteria that infect a remarkably diverse range of host species. Some representatives are significant pathogens of clinical or veter...

Update on neuromyelitis optica spectrum disorder.

Sep 10, 2020

Neuromyelitis optica spectrum disorder is an autoimmune disease that causes optic neuritis and transverse myelitis. Attacks can cause severe neurological damage leading to blindness and paralysis. Und...

Effectiveness and safety of early adjuvant amniotic membrane transplant versus standard antimicrobial treatment for infectious keratitis: a systematic review protocol.

Sep 10, 2020

The objective of this review is to systematically examine the effectiveness of early adjuvant amniotic membrane transplant versus standard antimicrobial therapy for infectious keratitis.Infectious ker...

Calcitriol inhibits apoptosis via activation of autophagy in hyperosmotic stress stimulated corneal epithelial cells in vivo and in vitro.

Sep 10, 2020

Previously, calcitriol has been demonstrated as a potential therapeutic agent for dry eye, whilst its role on corneal epithelium death remains unclear. This study aims to investigate the relationship ...

Genistein-Calcitriol Mitigates Hyperosmotic Stress-Induced TonEBP, CFTR Dysfunction, VDR Degradation and Inflammation in Dry Eye Disease.

Sep 10, 2020

Dry eye disease (DED) signs and symptoms are causally associated with increased ocular surface (OS) inflammation. Modulation of key regulators of aberrant OS inflammation is of interest for clinical m...

Eye pain in the white and quiet eye.

Sep 10, 2020

Eye pain is one of the most common presenting symptoms in ophthalmology. It can range from bothersome to debilitating for patients, and it can be vexing for clinicians, especially in the white and qui...

Bioceramic implant reduces intraocular VEGF levels.

Sep 10, 2020

Elevated intraocular levels of angiogenic cytokines such as vascular endothelial growth factor (VEGF) have been implicated the development of diabetic retinopathy. Over a decade of clinical evidence s...

Relationship between diabetic retinopathy and diabetic nephropathy; A longitudinal follow-up study from a tertiary care unit of Karachi, Pakistan.

Sep 10, 2020

To determine the development and progression of diabetic retinopathy in subjects with diabetic nephropathy.This retrospective longitudinal follow up study was conducted in outpatient department of Baq...