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Ophthalmology General

A Fairy Chemical Suppresses Retinal Angiogenesis as a HIF Inhibitor.

Oct 08, 2020

Neovascular retinal degeneration is a leading cause of blindness in advanced countries. Anti-vascular endothelial growth factor (VEGF) drugs have been used for neovascular retinal diseases; however, a...

Plastic Surgery and Cosmetic Procedures: Facial Injection Procedures.

Oct 08, 2020

Nonsurgical cosmetic procedures, including injection procedures, are among the fastest growing medical procedures. In 2018, botulinum toxin and hyaluronic acid injections were the two most common nons...

Moxifloxacin based axially swept wide-field fluorescence microscopy for high-speed imaging of conjunctival goblet cells.

Oct 08, 2020

Goblet cells (GCs) in the conjunctiva are specialized epithelial cells producing mucins on the ocular surface. GCs play important roles in maintaining homeostasis of the ocular surface, and GC dysfunc...

Profile of tear lipid mediator as a biomarker of inflammation for meibomian gland dysfunction and ocular surface diseases: Standard operating procedures.

Oct 08, 2020

Human tear is a biological fluid rich in lipids that is increasingly collected in clinical and biological research. The repertoire of small lipids or lipid mediators (often termed eicosanoids or oxyli...

An inadvertent issue of human retina exposure to endocrine disrupting chemicals: A safety assessment.

Oct 08, 2020

Endocrine disrupting chemicals (EDCs) are a group of chemical compounds that present a considerable public health problem due to their pervasiveness and associations with chronic diseases. EDCs can in...

An inhibitor of endothelial ETS transcription factors promotes physiologic and therapeutic vessel regression.

Oct 08, 2020

During the progression of ocular diseases such as retinopathy of prematurity and diabetic retinopathy, overgrowth of retinal blood vessels results in the formation of pathological neovascular tufts th...

A retrospective cohort study on the pathology and outcomes of type 2 diabetic patients with renal involvement.

Oct 08, 2020

To investigate the association of clinical and histological characteristics and the development of ESRD in T2DM patients with renal involvement.We conducted a retrospective analysis of clinical and pa...

Effectiveness of the Dexamethasone Implant in Lieu of Oral Corticosteroids in Intermediate and Posterior Uveitis Requiring Immunosuppression.

Oct 08, 2020

To evaluate dexamethasone intravitreal implant effectiveness in lieu of high-dose oral prednisone for short-term treatment of noninfectious intermediate and posterior uveitis in patients requiring imm...

Structural Variants Create New Topological-Associated Domains and Ectopic Retinal Enhancer-Gene Contact in Dominant Retinitis Pigmentosa.

Oct 08, 2020

The cause of autosomal-dominant retinitis pigmentosa (adRP), which leads to loss of vision and blindness, was investigated in families lacking a molecular diagnosis. A refined locus for adRP on Chr17q...

Clinical Outcomes and Prognostic Factors of Thai Retinoblastoma Patients.

Oct 08, 2020

Retinoblastoma (RB) outcomes in Thailand are unfavorable compared to those of developed countries. This study aims to determine whether the clinical outcomes of patients with RB significantly improved...

LncRNA H19 inhibits high glucose-induced inflammatory responses of human retinal epithelial cells by targeting miR-19b to increase SIRT1 expression.

Oct 08, 2020

Diabetic retinopathy (DR) is a common complication of diabetes mellitus. Inflammatory responses play crucial roles in the progress of DR. Long noncoding RNA (lncRNAs) and microRNAs (miRNAs) are key si...

Bone Marrow-Derived Mononuclear Cell Transplants Decrease Retinal Gliosis in Two Animal Models of Inherited Photoreceptor Degeneration.

Oct 05, 2020

Inherited photoreceptor degenerations are not treatable diseases and a frequent cause of blindness in working ages. In this study we investigate the safety, integration and possible rescue effects of ...

Updated definition and classification of dry eye disease: Renewed proposals using the nominal group and Delphi techniques.

Oct 05, 2020

The aim of our research was to obtain expert consensus for updated definition and classification of dry eye disease using formal methodology. The nominal group technique (NGT) involved a steering comm...

Association of ocular diseases with schizophrenia, bipolar disorder, and major depressive disorder: a retrospective case-control, population-based study.

Oct 05, 2020

Psychiatric disorders and ocular neurovascular diseases may share a similar pathophysiological route of vascular structures or neurological changes. The aim of this study is to investigate the associa...

Association between dietary antioxidants and risk for diabetic retinopathy in a Chinese population.

Oct 05, 2020

Diabetic retinopathy (DR) is related to oxidative stress and insufficient intake of dietary antioxidants may be associated with the onset and progression of DR. This study aimed to detect the associat...

Ocular surface diabetic disease: A neurogenic condition?

Oct 05, 2020

To investigate clinical and inflammatory changes in the ocular surface of insulin-dependent type I diabetic patients.Two hundred and nine eyes of 106 patients with diagnosis of type I diabetes were re...

Ocular rosacea.

Oct 05, 2020

To revisit ocular rosacea as an underappreciated condition which can cause permanent blindness if inadequately treated, and to review data supporting improved diagnostic and treatment strategies.Ocula...

Micro-interaction of mucin tear film interface with particles: The inconsistency of pharmacodynamics and precorneal retention of ion-exchange, functionalized, Mt-embedded nano- and microparticles.

Oct 05, 2020

Physiological reflexes and anatomical barriers render traditional eye drop delivery inefficient. We previously reported that drug-loaded nanoparticles and microspheres prepared from montmorillonite an...

Smoking Is Associated with Higher Intraocular Pressure Regardless of Glaucoma: A Retrospective Study of 12.5 Million Patients Using the Intelligent Research in Sight (IRIS®) Registry.

Oct 05, 2020

To compare the average intraocular pressure (IOP) among smokers, past smokers, and never smokers using the American Academy of Ophthalmology Intelligent Research in Sight (IRIS®) Registry.Retrospecti...

Mechanisms of Photoreceptor Death in Retinitis Pigmentosa.

Oct 01, 2020

Retinitis pigmentosa (RP) is the most common cause of inherited blindness and is characterised by the progressive loss of retinal photoreceptors. However, RP is a highly heterogeneous disease and, whi...